Recent Progress in Lipid Nanoparticles for Cancer Theranostics: Opportunity and Challenges

Theranostic Attributes of Acoustic Cluster Therapy and Its Use for Enhancing the Effectiveness of Liposomal Doxorubicin Treatment of Human Triple Negative Breast Cancer in Mice

(2020) Nigel Bush et al.   Frontiers in Pharmacology

Nanomedicines in Diagnosis and Treatment of Cancer: An Update

(2020) Nafis Haider et al.   CURRENT PHARMACEUTICAL DESIGN

99mTc-doxorubicin-loaded gallic acid-gold nanoparticles (99mTc-DOX-loaded GA-Au NPs) as a multifunctional theranostic agent

(2020) Walaa I. El-Ghareb et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Liposomal nanotheranostics for multimode targeted in vivo bioimaging and near‐infrared light mediated cancer therapy

(2020) Rajendra Prasad et al.   Communications Biology

99mTc-gallic-gold nanoparticles as a new imaging platform for tumor targeting

(2020) Tamer M. Sakr et al.   APPLIED RADIATION AND ISOTOPES

Diagnostic and therapeutic evaluation of folate-targeted paclitaxel and vinorelbine encapsulating theranostic liposomes for non-small cell lung cancer

(2020) Merve Karpuz et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Current Trends in Cancer Nanotheranostics: Metallic, Polymeric, and Lipid-Based Systems

(2019) Catarina Silva et al.   Pharmaceutics

A Versatile Theranostic Nanoemulsion for Architecture‐Dependent Multimodal Imaging and Dually Augmented Photodynamic Therapy

(2019) Yifan Zhang et al.   ADVANCED MATERIALS

Combinational Effects of Active Targeting, Shape, and Enhanced Permeability and Retention for Cancer Theranostic Nanocarriers

(2019) Armin Tahmasbi Rad et al.   ACS Applied Materials & Interfaces

Near-infrared absorbing nanoemulsions as nonlinear ultrasound contrast agents for cancer theranostics

(2019) Donald A. Fernandes et al.   JOURNAL OF MOLECULAR LIQUIDS

Intranasal teriflunomide microemulsion: An improved chemotherapeutic approach in glioblastoma

(2019) Dnyandev Gadhave et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Current Applications of Nanoemulsions in Cancer Therapeutics

(2019) Elena Sánchez-López et al.   Nanomaterials

Nanobubble Liposome Complexes for Diagnostic Imaging and Ultrasound-Triggered Drug Delivery in Cancers: A Theranostic Approach

(2019) Ameya Prabhakar et al.   ACS Omega

Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis

(2019) Catherine de Martel et al.   Lancet Global Health

In Vitro and In Vivo evaluation of a novel folate-targeted theranostic nanoemulsion of docetaxel for imaging and improved anticancer activity against ovarian cancers

(2018) Niravkumar R. Patel et al.   CANCER BIOLOGY & THERAPY

Liposomally formulated phospholipid-conjugated novel near-infrared fluorescence probe for particle size effect on cellular uptake and biodistribution in vivo

(2018) Jing Xing et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

In vitro neuroprotective effects of naringenin nanoemulsion against β-amyloid toxicity through the regulation of amyloidogenesis and tau phosphorylation

(2018) Shadab Md et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Recent trends of nanomedicinal approaches in clinics

(2018) Fahima Dilnawaz et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Liposomes: Clinical Applications and Potential for Image-Guided Drug Delivery

(2018) Narottam Lamichhane et al.   MOLECULES

PEG-copolymer-coated iron oxide nanoparticles that avoid the reticuloendothelial system and act as kidney MRI contrast agents

(2018) Vanessa Gómez-Vallejo et al.   Nanoscale

Progress and challenges towards targeted delivery of cancer therapeutics

(2018) Daniel Rosenblum et al.   Nature Communications

Bioinspired Multifunctional Melanin-Based Nanoliposome for Photoacoustic/Magnetic Resonance Imaging-Guided Efficient Photothermal Ablation of Cancer

(2018) Liang Zhang et al.   Theranostics

Bio-inspired drug delivery systems: an emerging platform for targeted cancer therapy

(2018) Gella Maelys Ngandeu Neubi et al.   Biomaterials Science

Current Trends and Challenges in the Clinical Translation of Nanoparticulate Nanomedicines: Pathways for Translational Development and Commercialization

(2018) Susan Hua et al.   Frontiers in Pharmacology

Risk Assessment and Risk Minimization in Nanomedicine: A Need for Predictive, Alternative, and 3Rs Strategies

(2018) Lisa Accomasso et al.   Frontiers in Pharmacology

Red-Light-Controlled Release of Drug-Ru Complex Conjugates from Metallopolymer Micelles for Phototherapy in Hypoxic Tumor Environments

(2018) Wen Sun et al.   ADVANCED FUNCTIONAL MATERIALS

Biosynthesis of Metal Nanoparticles via Microbial Enzymes: A Mechanistic Approach

(2018) Muhammad Ovais et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lactoferrin-tagged quantum dots-based theranostic nanocapsules for combined COX-2 inhibitor/herbal therapy of breast cancer

(2018) Ahmed S AbdElhamid et al.   Nanomedicine

Nanoemulsion: A Novel Eon in Cancer Chemotherapy

(2017) Prashant Sahu et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Safety against nephrotoxicity in paclitaxel treatment: Oral nanocarrier as an effective tool in preclinical evaluation with marked in vivo antitumor activity

(2017) Hira Choudhury et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Towards clinically translatable in vivo nanodiagnostics

(2017) Seung-min Park et al.   Nature Reviews Materials

Gold conjugate-based liposomes with hybrid cluster bomb structure for liver cancer therapy

(2016) Ning Zhang et al.   BIOMATERIALS

Nanoparticle-based drug delivery systems: a commercial and regulatory outlook as the field matures

(2016) Héloïse Ragelle et al.   Expert Opinion on Drug Delivery

To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?

(2016) F. Danhier   JOURNAL OF CONTROLLED RELEASE

Comparison of complement activation-related pseudoallergy in miniature and domestic pigs: foundation of a validatable immune toxicity model

(2016) Joshua A. Jackman et al.   Nanomedicine-Nanotechnology Biology and Medicine

Coloured cornea replacements with anti-infective properties: expanding the safe use of silver nanoparticles in regenerative medicine

(2016) E. I. Alarcon et al.   Nanoscale

Analysis of nanoparticle delivery to tumours

(2016) Stefan Wilhelm et al.   Nature Reviews Materials

Positron Emission Tomography Based Elucidation of the Enhanced Permeability and Retention Effect in Dogs with Cancer Using Copper-64 Liposomes

(2015) Anders E. Hansen et al.   ACS Nano

Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity

(2015) Hiroshi Maeda   ADVANCED DRUG DELIVERY REVIEWS

Complement activation as a bioequivalence issue relevant to the development of generic liposomes and other nanoparticulate drugs

(2015) Janos Szebeni et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulatory aspects on nanomedicines

(2015) Vanessa Sainz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Self-Assembling Polymer Micelle/Clay Nanodisk/Doxorubicin Hybrid Injectable Gels for Safe and Efficient Focal Treatment of Cancer

(2015) Koji Nagahama et al.   BIOMACROMOLECULES

Gold Nanomaterials at Work in Biomedicine

(2015) Xuan Yang et al.   CHEMICAL REVIEWS

A challenge for theranostics: is the optimal particle for therapy also optimal for diagnostics?

(2015) Tamar Dreifuss et al.   Nanoscale

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Endocytosis of a Functionally Enhanced GFP-Tagged Transferrin Receptor in CHO Cells

(2015) Qi He et al.   PLoS One

Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity

(2015) Biswanath Majumder et al.   Nature Communications

Ruthenium-Containing Block Copolymer Assemblies: Red-Light-Responsive Metallopolymers with Tunable Nanostructures for Enhanced Cellular Uptake and Anticancer Phototherapy

(2015) Wen Sun et al.   Advanced Healthcare Materials

Nanomedicines: addressing the scientific and regulatory gap

(2014) Sally Tinkle et al.   Annals of the New York Academy of Sciences

The importance of nanoparticle shape in cancer drug delivery

(2014) Nghia P Truong et al.   Expert Opinion on Drug Delivery

Liposomes versus Lipid Nanoparticles: Comparative Study of Lipid-Based Systems as Oryzalin Carriers for the Treatment of Leishmaniasis

(2014) R. M. Lopes et al.   Journal of Biomedical Nanotechnology

Transferrin Receptor-Mediated Endocytosis: A Useful Target for Cancer Therapy

(2014) Stephanie Tortorella et al.   JOURNAL OF MEMBRANE BIOLOGY

Size-Dependent Antimicrobial Effects of Novel Palladium Nanoparticles

(2014) Clara P. Adams et al.   PLoS One

Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA

(2014) J. E. Zuckerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticle-Enabled, Image-Guided Treatment Planning of Target Specific RNAi Therapeutics in an Orthotopic Prostate Cancer Model

(2014) Qiaoya Lin et al.   Small

Gold Nanocrystal Labeling Allows Low-Density Lipoprotein Imaging from the Subcellular to Macroscopic Level

(2013) Iris E. Allijn et al.   ACS Nano

Magnetically engineered Cd-free quantum dots as dual-modality probes for fluorescence/magnetic resonance imaging of tumors

(2013) Ke Ding et al.   BIOMATERIALS

Delivery of therapeutic nucleic acids via transferrin and transferrin receptors: lipoplexes and other carriers

(2013) Conchita Tros de Ilarduya et al.   Expert Opinion on Drug Delivery

Improvement of cellular uptake, in vitro antitumor activity and sustained release profile with increased bioavailability from a nanoemulsion platform

(2013) Hira Choudhury et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles

(2013) Mark J. Ernsting et al.   JOURNAL OF CONTROLLED RELEASE

Formulation design and evaluation of quantum dot-loaded nanostructured lipid carriers for integrating bioimaging and anticancer therapy

(2013) Shu-Hui Hsu et al.   Nanomedicine

Mammalian cells preferentially internalize hydrogel nanodiscs over nanorods and use shape-specific uptake mechanisms

(2013) R. Agarwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Correlating preclinical animal studies and human clinical trials of a multifunctional, polymeric nanoparticle

(2013) S. Eliasof et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recent trends in the use of lipidic nanoparticles as pharmaceutical carriers for cancer therapy and diagnostics

(2013) Samuel V. Mussi et al.   Journal of Materials Chemistry B

Liposome imaging agents in personalized medicine

(2012) Anncatrine L. Petersen et al.   ADVANCED DRUG DELIVERY REVIEWS

Structure and dynamics of drug carriers and their interaction with cellular receptors: Focus on serum transferrin

(2012) Ashley N. Luck et al.   ADVANCED DRUG DELIVERY REVIEWS

Generation and functional characterization of the anti-transferrin receptor single-chain antibody-GAL4 (TfRscFv-GAL4) fusion protein

(2012) Qing Ye et al.   BMC BIOTECHNOLOGY

Gold Nanoparticle–Mediated Detection of Circulating Cancer Cells

(2012) Kiran Bhattacharyya et al.   CLINICS IN LABORATORY MEDICINE

A novel lipid-based nanomicelle of docetaxel: evaluation of antitumor activity and biodistribution

(2012) Mingshu Ma et al.   International Journal of Nanomedicine

The influence of size, shape and vessel geometry on nanoparticle distribution

(2012) Jifu Tan et al.   Microfluidics and Nanofluidics

Odyssey of a cancer nanoparticle: From injection site to site of action

(2012) Joseph W. Nichols et al.   Nano Today

Preclinical Development and Clinical Translation of a PSMA-Targeted Docetaxel Nanoparticle with a Differentiated Pharmacological Profile

(2012) J. Hrkach et al.   Science Translational Medicine

A Novel Solid Lipid Nanoparticle Formulation for Active Targeting to Tumor αvβ3Integrin Receptors Reveals Cyclic RGD as A Double-Edged Sword

(2012) Adam J. Shuhendler et al.   Advanced Healthcare Materials

Optically Traceable Solid Lipid Nanoparticles Loaded with siRNA and Paclitaxel for Synergistic Chemotherapy with In situ Imaging

(2012) Ki Hyun Bae et al.   Advanced Healthcare Materials

Oxide and hybrid nanostructures for therapeutic applications

(2011) Sudeshna Chandra et al.   ADVANCED DRUG DELIVERY REVIEWS

Novel Method to Label Solid Lipid Nanoparticles with64Cu for Positron Emission Tomography Imaging

(2011) Erica Andreozzi et al.   BIOCONJUGATE CHEMISTRY

Attenuation of nontargeted cell-kill using a high-density lipoprotein-mimicking peptide–phospholipid nanoscaffold

(2011) Mi Yang et al.   Nanomedicine

Differential Expression of Transferrin Receptor (TfR) in a Spectrum of Normal to Malignant Breast Tissues

(2011) Meenakshi Singh et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Viral specific cytotoxic T cells inhibit the growth of TfR-expressing tumor cells with antibody targeted viral peptide/HLA-A2 complex

(2010) Jianan Li et al.   CELLULAR IMMUNOLOGY

RGD peptide functionalized and reconstituted high-density lipoprotein nanoparticles as a versatile and multimodal tumor targeting molecular imaging probe

(2010) Wei Chen et al.   FASEB JOURNAL

Freestanding palladium nanosheets with plasmonic and catalytic properties

(2010) Xiaoqing Huang et al.   Nature Nanotechnology

Nanomedicine-Challenge and Perspectives

(2009) Kristina Riehemann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biomimetic Nanocarrier for Direct Cytosolic Drug Delivery

(2009) Zhihong Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Lipid nanocapsules: A new platform for nanomedicine

(2009) N.T. Huynh et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Quantum Dots for In Vivo Small-Animal Imaging

(2009) L. A. Bentolila et al.   JOURNAL OF NUCLEAR MEDICINE

Tumor Targeting of Functionalized Quantum Dot−Liposome Hybrids by Intravenous Administration

(2009) Wafa’ T. Al-Jamal et al.   MOLECULAR PHARMACEUTICS

Targeting Hypoxia-inducible Factor-1α With Tf–PEI–shRNA Complex via Transferrin Receptor–mediated Endocytosis Inhibits Melanoma Growth

(2008) Yeqiang Liu et al.   MOLECULAR THERAPY

Microfluidic Platform for Controlled Synthesis of Polymeric Nanoparticles

(2008) Rohit Karnik et al.   NANO LETTERS