Recent Advances in Experimental Dendritic Cell Vaccines for Cancer

Tumor-associated antigen-based personalized dendritic cell vaccine in solid tumor patients

(2020) Qian-Ting Wang et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Autologous monocyte-derived DC vaccination combined with cisplatin in stage III and IV melanoma patients: a prospective, randomized phase 2 trial

(2020) Steve Boudewijns et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Dendritic Cells and Their Role in Immunotherapy

(2020) Alycia Gardner et al.   Frontiers in Immunology

A randomized controlled phase II clinical trial on mRNA electroporated autologous monocyte-derived dendritic cells (TriMixDC-MEL) as adjuvant treatment for stage III/IV melanoma patients who are disease-free following the resection of macrometastases

(2020) Yanina Jansen et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Dendritic Cell-based Immunotherapy Pulsed With Wilms Tumor 1 Peptide and Mucin 1 as an Adjuvant Therapy for Pancreatic Ductal Adenocarcinoma After Curative Resection: A Phase I/IIa Clinical Trial

(2020) KAZUHIRO NAGAI et al.   ANTICANCER RESEARCH

Novel adjuvant dendritic cell therapy with transfection of heat-shock protein 70 messenger RNA for patients with hepatocellular carcinoma: a phase I/II prospective randomized controlled clinical trial

(2020) Hiroto Matsui Matsui et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Th17-inducing autologous dendritic cell vaccination promotes antigen-specific cellular and humoral immunity in ovarian cancer patients

(2020) Matthew S. Block et al.   Nature Communications

Current Trends in Cancer Immunotherapy

(2020) Ivan Y. Filin et al.   Biomedicines

Clinical and Antitumor Immune Responses in Relapsed/Refractory Follicular Lymphoma Patients after Intranodal Injections of IFNα-Dendritic Cells and Rituximab

(2019) M. Christina Cox et al.   CLINICAL CANCER RESEARCH

Dendritic Cell Vaccination in Metastatic Melanoma Turns “Non-T Cell Inflamed” Into “T-Cell Inflamed” Tumors

(2019) Jenny Bulgarelli et al.   Frontiers in Immunology

Assessment of Immune Response Following Dendritic Cell-Based Immunotherapy in Pediatric Patients With Relapsing Sarcoma

(2019) Lenka Fedorova et al.   Frontiers in Oncology

Dendritic Cell-Based Immunotherapy in Advanced Sarcoma and Neuroblastoma Pediatric Patients: Anti-cancer Treatment Preceding Monocyte Harvest Impairs the Immunostimulatory and Antigen-Presenting Behavior of DCs and Manufacturing Process Outcome

(2019) Eva Hlavackova et al.   Frontiers in Oncology

First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma

(2018) Linda M. Liau et al.   Journal of Translational Medicine

EVIR: chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens

(2018) Mario Leonardo Squadrito et al.   NATURE METHODS

Therapeutic Prospects of Extracellular Vesicles in Cancer Treatment

(2018) Daria S. Chulpanova et al.   Frontiers in Immunology

Intratumoral Lentivector-Mediated TGF-β1 Gene Downregulation As a Potent Strategy for Enhancing the Antitumor Effect of Therapy Composed of Cyclophosphamide and Dendritic Cells

(2017) Joanna Rossowska et al.   Frontiers in Immunology

Phase II Study of Autologous Monocyte-Derived mRNA Electroporated Dendritic Cells (TriMixDC-MEL) Plus Ipilimumab in Patients With Pretreated Advanced Melanoma

(2016) Sofie Wilgenhof et al.   JOURNAL OF CLINICAL ONCOLOGY

Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells

(2015) G. Schreibelt et al.   CLINICAL CANCER RESEARCH

Dendritic cell vaccine treatment for indolent B-cell non-Hodgkin lymphoma: clinical trial in progress

(2015) Yi Lin et al.   CYTOTHERAPY

DCVax®-L—Developed by Northwest Biotherapeutics

(2014) Stavros Polyzoidis et al.   Human Vaccines & Immunotherapeutics

A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients

(2013) S. Wilgenhof et al.   ANNALS OF ONCOLOGY

Topical TLR7 Agonist Imiquimod Can Induce Immune-Mediated Rejection of Skin Metastases in Patients with Breast Cancer

(2012) S. Adams et al.   CLINICAL CANCER RESEARCH

Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape

(2012) J. M. Taube et al.   Science Translational Medicine

Induction of CD8+ T-Cell Responses Against Novel Glioma–Associated Antigen Peptides and Clinical Activity by Vaccinations With α-Type 1 Polarized Dendritic Cells and Polyinosinic-Polycytidylic Acid Stabilized by Lysine and Carboxymethylcellulose in Patients With Recurrent Malignant Glioma

(2010) Hideho Okada et al.   JOURNAL OF CLINICAL ONCOLOGY

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Understanding human myeloid dendritic cell subsets for the rational design of novel vaccines

(2009) Eynav Klechevsky et al.   HUMAN IMMUNOLOGY

Directing dendritic cell immunotherapy towards successful cancer treatment

(2009) Rachel Lubong Sabado et al.   Immunotherapy

Human Flt-3 ligand-mobilized dendritic cells require additional activation to drive effective immune responses

(2007) Kerrilyn R. Diener et al.   EXPERIMENTAL HEMATOLOGY