Identification of Flap Endonuclease 1 With Diagnostic and Prognostic Value in Breast Cancer

Diagnostic value of serum glypican-3 alone and in combination with AFP as an aid in the diagnosis of liver cancer

(2020) Shuxia Liu et al.   CLINICAL BIOCHEMISTRY

Tumor markers CA15-3, CA125, CEA and breast cancer survival by molecular subtype: a cohort study

(2020) Junxian Li et al.   Breast Cancer

MST1R (RON) expression is a novel prognostic biomarker for metastatic progression in breast cancer patients

(2020) Brian G. Hunt et al.   BREAST CANCER RESEARCH AND TREATMENT

Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer

(2020) Koen D. Flach et al.   CANCER RESEARCH

Flap endonuclease 1 (FEN1) as a novel diagnostic and prognostic biomarker for gastric cancer

(2020) Enfa Zhao et al.   Clinics and Research in Hepatology and Gastroenterology

Biological and clinical significance of flap endonuclease‑1 in triple‑negative breast cancer: Support of metastasis and a poor prognosis

(2020) Lu Xu et al.   ONCOLOGY REPORTS

The association of five preoperative serum tumor markers and pathological features in patients with breast cancer

(2019) Mingjian Lian et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

FEN1 mediates miR-200a methylation and promotes breast cancer cell growth via MET and EGFR signaling

(2019) Xue Zeng et al.   FASEB JOURNAL

Quality and efficiency assessment of six extracellular vesicle isolation methods by nano-flow cytometry

(2019) Ye Tian et al.   Journal of Extracellular Vesicles

Overexpression of Flap Endonuclease 1 Correlates with Enhanced Proliferation and Poor Prognosis of Non–Small-Cell Lung Cancer

(2018) Keqiang Zhang et al.   AMERICAN JOURNAL OF PATHOLOGY

The future of blood-based biomarkers for the early detection of breast cancer

(2018) Sau Yeen Loke et al.   EUROPEAN JOURNAL OF CANCER

Extracellular HMGB1 as a therapeutic target in inflammatory diseases

(2018) Ulf Andersson et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Improved sensitivity for detection of breast cancer by combination of miR-34a and tumor markers CA 15-3 or CEA

(2018) Martin Zaleski et al.   Oncotarget

Versatile Types of DNA-Based Nanobiosensors for Specific Detection of Cancer Biomarker FEN1 in Living Cells and Cell-Free Systems

(2018) Hao Zhang et al.   NANO LETTERS

Control of structure-specific endonucleases to maintain genome stability

(2017) Pierre-Marie Dehé et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Complementation of aprataxin deficiency by base excision repair enzymes in mitochondrial extracts

(2017) Melike Çağlayan et al.   NUCLEIC ACIDS RESEARCH

Phosphate steering by Flap Endonuclease 1 promotes 5′-flap specificity and incision to prevent genome instability

(2017) Susan E. Tsutakawa et al.   Nature Communications

Serum CA125 is a predictive marker for breast cancer outcomes and correlates with molecular subtypes

(2017) Cheng Fang et al.   Oncotarget

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

(2017) Darshan S. Chandrashekar et al.   NEOPLASIA

The Significance of CA15-3 in Breast Cancer Patients and its Relationship to HER-2 Receptor Status

(2017) Z.M. Hashim   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Interaction between APC and Fen1 during breast carcinogenesis

(2016) Satya Narayan et al.   DNA REPAIR

Resolving individual steps of Okazaki-fragment maturation at a millisecond timescale

(2016) Joseph L Stodola et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation

(2016) H Sun et al.   ONCOGENE

Resolving individual steps of Okazaki-fragment maturation at a millisecond timescale

(2016) Joseph L Stodola et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression

(2016) Lingfeng He et al.   EBioMedicine

Flap endonuclease 1 is a promising candidate biomarker in gastric cancer and is involved in cell proliferation and apoptosis

(2014) KEJIA WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer

(2014) Tarek M.A. Abdel-Fatah et al.   Molecular Oncology

The FEN1 E359K germline mutation disrupts the FEN1–WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers

(2014) L Chung et al.   ONCOGENE

Serum levels of CEA and CA15-3 in different molecular subtypes and prognostic value in Chinese breast cancer

(2013) San-gang Wu et al.   BREAST

Serum tumour markers as a diagnostic and prognostic tool in Libyan breast cancer

(2012) Mohamed Elfagieh et al.   TUMOR BIOLOGY

Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011

(2011) A. Goldhirsch et al.   ANNALS OF ONCOLOGY

Functional FEN1 genetic variants contribute to risk of hepatocellular carcinoma, esophageal cancer, gastric cancer and colorectal cancer

(2011) L. Liu et al.   CARCINOGENESIS

Functional regulation of FEN1 nuclease and its link to cancer

(2010) L. Zheng et al.   NUCLEIC ACIDS RESEARCH

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

FunctionalFEN1polymorphisms are associated with DNA damage levels and lung cancer risk

(2009) Ming Yang et al.   HUMAN MUTATION

Survival in patients with brain metastases from breast cancer

(2008) April F. Eichler et al.   CANCER

Long-term prognostic study of carcinoembryonic antigen (CEA) and carbohydrate antigen 15-3 (CA 15-3) in breast cancer

(2008) Masahiro Uehara et al.   International Journal of Clinical Oncology