Biological Significance of YAP/TAZ in Pancreatic Ductal Adenocarcinoma
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Title
Biological Significance of YAP/TAZ in Pancreatic Ductal Adenocarcinoma
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-07-30
DOI
10.3389/fonc.2021.700315
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Note: Only part of the references are listed.- Yap1-2 Isoform Is the Primary Mediator in TGF-β1 Induced EMT in Pancreatic Cancer
- (2021) Chao Gao et al. Frontiers in Oncology
- YAP1 is an independent prognostic marker in pancreatic cancer and associated with extracellular matrix remodeling
- (2020) Qimin Zhou et al. Journal of Translational Medicine
- Isoprenylcysteine carboxylmethyltransferase is required for the impact of mutant KRAS on TAZ protein level and cancer cell self-renewal
- (2020) Tin Fan Chai et al. ONCOGENE
- KRASG12C Inhibition with Sotorasib in Advanced Solid Tumors
- (2020) David S. Hong et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Statin Use and Risk of Pancreatic Cancer
- (2019) Yun Zhang et al. PANCREAS
- FDA Approval Summary: Pembrolizumab for the treatment of microsatellite instability-high solid tumors
- (2019) Leigh Marcus et al. CLINICAL CANCER RESEARCH
- Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair–Deficient Cancer: Results From the Phase II KEYNOTE-158 Study
- (2019) Aurelien Marabelle et al. JOURNAL OF CLINICAL ONCOLOGY
- Targeting Tumor Metabolism With Statins During Treatment for Advanced-stage Pancreatic Cancer
- (2018) Nick A. Iarrobino et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- SPON2 Promotes M1-like Macrophage Recruitment and Inhibits Hepatocellular Carcinoma Metastasis by Distinct Integrin–Rho GTPase–Hippo Pathways
- (2018) Yan-Li Zhang et al. CANCER RESEARCH
- The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1
- (2018) Helena J. Janse van Rensburg et al. CANCER RESEARCH
- Prediagnosis Use of Statins Associates With Increased Survival Times of Patients With Pancreatic Cancer
- (2018) Tsuyoshi Hamada et al. Clinical Gastroenterology and Hepatology
- Effect of Metformin and Statin Use on Survival in Pancreatic Cancer Patients: a Systematic Literature Review and Meta-analysis
- (2018) Jian-Yu E et al. CURRENT MEDICINAL CHEMISTRY
- The relationship between the use of statins and mortality, severity, and pancreatic cancer in Danish patients with chronic pancreatitis
- (2018) Ulrich C. Bang et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell
- (2018) Steven W. Plouffe et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Statin use and pancreatic cancer risk in two prospective cohort studies
- (2018) Tsuyoshi Hamada et al. JOURNAL OF GASTROENTEROLOGY
- The Interface of Pancreatic Cancer With Diabetes, Obesity, and Inflammation
- (2018) James L. Abbruzzese et al. PANCREAS
- Obesity and Pancreatic Cancer
- (2018) Mu Xu et al. PANCREAS
- The Hippo pathway in normal development and cancer
- (2018) Marcello Maugeri-Saccà et al. PHARMACOLOGY & THERAPEUTICS
- Pseudolaric Acid B Inhibits Proliferation, Invasion and Epithelial-to-Mesenchymal Transition in Human Pancreatic Cancer Cell
- (2018) Xiaoyu Li et al. YONSEI MEDICAL JOURNAL
- YAP Is Essential for Treg-Mediated Suppression of Antitumor Immunity
- (2018) Xuhao Ni et al. Cancer Discovery
- Hippo pathway affects survival of cancer patients: extensive analysis of TCGA data and review of literature
- (2018) Anello Marcello Poma et al. Scientific Reports
- YAP-Induced PD-L1 Expression Drives Immune Evasion in BRAFi-Resistant Melanoma
- (2018) Min Hwan Kim et al. Cancer Immunology Research
- Rapping about Mechanotransduction
- (2018) Consuelo Ibar et al. DEVELOPMENTAL CELL
- Pancreatic Ductal Adenocarcinoma and Its Precursor Lesions
- (2018) Bing Ren et al. AMERICAN JOURNAL OF PATHOLOGY
- Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer
- (2018) Yumeng Wang et al. Cell Reports
- Hypermutation In Pancreatic Cancer
- (2017) Jeremy L. Humphris et al. GASTROENTEROLOGY
- Experimental models of pancreatic cancer desmoplasia
- (2017) Sujit Suklabaidya et al. LABORATORY INVESTIGATION
- Insulin Receptor and GPCR Crosstalk Stimulates YAP via PI3K and PKD in Pancreatic Cancer Cells
- (2017) Fang Hao et al. MOLECULAR CANCER RESEARCH
- Mechanobiology of YAP and TAZ in physiology and disease
- (2017) Tito Panciera et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Immunology: Hippo signalling influences T cell fate
- (2017) Sarah Onuora Nature Reviews Rheumatology
- Overexpression of Yes Associated Protein 1, an Independent Prognostic Marker in Patients With Pancreatic Ductal Adenocarcinoma, Correlated With Liver Metastasis and Poor Prognosis
- (2017) Maria Teresa Salcedo Allende et al. PANCREAS
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
- Hypoxia induces oncogene yes-associated protein 1 nuclear translocation to promote pancreatic ductal adenocarcinoma invasion via epithelial–mesenchymal transition
- (2017) Honglong Wei et al. TUMOR BIOLOGY
- Preoperative predictors for early recurrence of resectable pancreatic cancer
- (2017) Kohei Nishio et al. World Journal of Surgical Oncology
- Stiehopus japonieus acidic mucopolysaccharide inhibits the proliferation of pancreatic cancer SW1990 cells through Hippo-YAP pathway
- (2017) Xiaoyu Li et al. Oncotarget
- YAP regulates PD-L1 expression in human NSCLC cells
- (2017) Jinbai Miao et al. Oncotarget
- The Role of Cholesterol in Cancer
- (2016) Omer F. Kuzu et al. CANCER RESEARCH
- Analysis of Hippo and TGFβ signaling in polarizing epithelial cells and mouse embryos
- (2016) Masahiro Narimatsu et al. DIFFERENTIATION
- Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction
- (2016) Sirio Dupont EXPERIMENTAL CELL RESEARCH
- YAP1 and TAZ Control Pancreatic Cancer Initiation in Mice by Direct Up-regulation of JAK–STAT3 Signaling
- (2016) Ralph Gruber et al. GASTROENTEROLOGY
- Genetics and biology of pancreatic ductal adenocarcinoma
- (2016) Haoqiang Ying et al. GENES & DEVELOPMENT
- The Landscape of Pancreatic Cancer Therapeutic Resistance Mechanisms
- (2016) Saswati Chand et al. International Journal of Biological Sciences
- Impact of statin use on cancer recurrence and mortality in breast cancer: A systematic review and meta-analysis
- (2016) Sashidhar Manthravadi et al. INTERNATIONAL JOURNAL OF CANCER
- Statin attenuates cell proliferative ability via TAZ (WWTR1) in hepatocellular carcinoma
- (2016) Takaaki Higashi et al. MEDICAL ONCOLOGY
- Statin Use and Its Impact on Survival in Pancreatic Cancer Patients
- (2016) Hee Seung Lee et al. MEDICINE
- TGF-β Targets the Hippo Pathway Scaffold RASSF1A to Facilitate YAP/SMAD2 Nuclear Translocation
- (2016) Dafni-Eleftheria Pefani et al. MOLECULAR CELL
- A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
- (2016) Faiyaz Notta et al. NATURE
- Yes-associated protein mediates immune reprogramming in pancreatic ductal adenocarcinoma
- (2016) S Murakami et al. ONCOGENE
- New insights into posttranslational modifications of Hippo pathway in carcinogenesis and therapeutics
- (2016) Mingjing He et al. Cell Division
- ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types
- (2016) Waltraut Lehmann et al. Nature Communications
- YAP Inhibition by Resveratrol via Activation of AMPK Enhances the Sensitivity of Pancreatic Cancer Cells to Gemcitabine
- (2016) Zhengdong Jiang et al. Nutrients
- The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level
- (2016) Natthakan Thongon et al. Oncotarget
- Antitumor activity of curcumin is involved in down-regulation of YAP/TAZ expression in pancreatic cancer cells
- (2016) Xiuxia Zhou et al. Oncotarget
- Effect of Lipophilic and Hydrophilic Statins on Breast Cancer Risk in Thai Women: A Cross-sectional Study
- (2016) Thunyarat Anothaisintawee et al. Journal of Cancer
- Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation
- (2016) Qiang Zhang et al. NEOPLASIA
- Impact of Statin Use on Survival in Patients Undergoing Resection for Early-Stage Pancreatic Cancer
- (2015) Bechien U Wu et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Statin use and risk of pancreatic cancer: Results from a large, clinic-based case-control study
- (2015) Evan J. Walker et al. CANCER
- Abstract 619: Identification of clinically actionable genomic alterations in the tumor and circulation of pancreatic cancer patients
- (2015) Mark Sausen et al. CANCER RESEARCH
- An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell-like Behaviors Contributing to Disease Progression
- (2015) H. Hayashi et al. CANCER RESEARCH
- Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
- (2015) Fa-Xing Yu et al. CELL
- Tissue Transglutaminase Mediated Tumor-Stroma Interaction Promotes Pancreatic Cancer Progression
- (2015) J. Lee et al. CLINICAL CANCER RESEARCH
- Statins and the risk of pancreatic cancer in Type 2 diabetic patients-A population-based cohort study
- (2015) Mei-Jyh Chen et al. INTERNATIONAL JOURNAL OF CANCER
- YAP overexpression promotes the epithelial-mesenchymal transition and chemoresistance in pancreatic cancer cells
- (2015) YANLI YUAN et al. Molecular Medicine Reports
- Whole genomes redefine the mutational landscape of pancreatic cancer
- (2015) Nicola Waddell et al. NATURE
- Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets
- (2015) Agnieszka K. Witkiewicz et al. Nature Communications
- Hippo transducer TAZ promotes epithelial mesenchymal transition and supports pancreatic cancer progression
- (2015) Dacheng Xie et al. Oncotarget
- Upregulation of miR-181c contributes to chemoresistance in pancreatic cancer by inactivating the Hippo signaling pathway
- (2015) Meiyuan Chen et al. Oncotarget
- Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3
- (2015) Shuping Yang et al. Oncotarget
- Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis
- (2015) Susan Morvaridi et al. Scientific Reports
- The Association of Statin Use after Cancer Diagnosis with Survival in Pancreatic Cancer Patients: A SEER-Medicare Analysis
- (2015) Christie Y. Jeon et al. PLoS One
- Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer
- (2014) Avnish Kapoor et al. CELL
- KRAS and YAP1 Converge to Regulate EMT and Tumor Survival
- (2014) Diane D. Shao et al. CELL
- YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth
- (2014) Boon Chuan Low et al. FEBS LETTERS
- Targeted depletion of an MDSC subset unmasks pancreatic ductal adenocarcinoma to adaptive immunity
- (2014) Ingunn M Stromnes et al. GUT
- Metabolic control of YAP and TAZ by the mevalonate pathway
- (2014) Giovanni Sorrentino et al. NATURE CELL BIOLOGY
- Downstream of Mutant KRAS, the Transcription Regulator YAP Is Essential for Neoplastic Progression to Pancreatic Ductal Adenocarcinoma
- (2014) W. Zhang et al. Science Signaling
- Association between statin use and colorectal cancer risk: a meta-analysis of 42 studies
- (2013) Yanqiong Liu et al. CANCER CAUSES & CONTROL
- Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner
- (2013) T. A. Mace et al. CANCER RESEARCH
- The Differential Effects of Statins on the Risk of Developing Pancreatic Cancer: A Case–Control Study in Two Centres in the United Kingdom
- (2013) F. J. Carey et al. DIGESTIVE DISEASES AND SCIENCES
- Hippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas
- (2013) Tao Gao et al. GASTROENTEROLOGY
- Genetic Alterations Associated With Progression From Pancreatic Intraepithelial Neoplasia to Invasive Pancreatic Tumor
- (2013) Stephen J. Murphy et al. GASTROENTEROLOGY
- Roles for KRAS in Pancreatic Tumor Development and Progression
- (2013) Marina Pasca di Magliano et al. GASTROENTEROLOGY
- Epithelial-mesenchymal plasticity in carcinoma metastasis
- (2013) J. H. Tsai et al. GENES & DEVELOPMENT
- Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine
- (2013) Daniel D. Von Hoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- Simvastatin delay progression of pancreatic intraepithelial neoplasia and cancer formation in a genetically engineered mouse model of pancreatic cancer
- (2013) Volker Fendrich et al. PANCREATOLOGY
- CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer
- (2013) A. Neesse et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of TAZ as Mediator of Wnt Signaling
- (2012) Luca Azzolin et al. CELL
- Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway
- (2012) William A. Freed-Pastor et al. CELL
- Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
- (2012) Haoqiang Ying et al. CELL
- YAP regulates neuronal differentiation through Sonic hedgehog signaling pathway
- (2012) Yi-Ting Lin et al. EXPERIMENTAL CELL RESEARCH
- What We Have Learned About Pancreatic Cancer From Mouse Models
- (2012) Pedro A. Pérez–Mancera et al. GASTROENTEROLOGY
- Presence of Somatic Mutations in Most Early-Stage Pancreatic Intraepithelial Neoplasia
- (2012) Mitsuro Kanda et al. GASTROENTEROLOGY
- Atorvastatin delays progression of pancreatic lesions to carcinoma by regulating PI3/AKT signaling in p48Cre/+ LSL-KrasG12D/+ mice
- (2012) Altaf Mohammed et al. INTERNATIONAL JOURNAL OF CANCER
- Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice
- (2012) Meredith A. Collins et al. JOURNAL OF CLINICAL INVESTIGATION
- TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth
- (2012) Makiko Fujii et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Hippo Signaling Regulates Pancreas Development through Inactivation of Yap
- (2012) N. M. George et al. MOLECULAR AND CELLULAR BIOLOGY
- Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
- (2012) Andrew V. Biankin et al. NATURE
- Down-Regulation of Yes Associated Protein 1 Expression Reduces Cell Proliferation and Clonogenicity of Pancreatic Cancer Cells
- (2012) Caroline H. Diep et al. PLoS One
- Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell
- (2012) J. E. D. Thaventhiran et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Hippo pathway controls polar cell fate through Notch signaling during Drosophila oogenesis
- (2011) Hsi-Ju Chen et al. DEVELOPMENTAL BIOLOGY
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
- (2011) Thierry Conroy et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Hippo Pathway Regulates Wnt/β-Catenin Signaling
- (2010) Xaralabos Varelas et al. DEVELOPMENTAL CELL
- The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway
- (2010) Xaralabos Varelas et al. DEVELOPMENTAL CELL
- A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP
- (2010) B. Zhao et al. GENES & DEVELOPMENT
- Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver
- (2010) L. Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dysregulation of the mevalonate pathway promotes transformation
- (2010) J. W. Clendening et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
- (2009) A. Fernandez-L et al. GENES & DEVELOPMENT
- TAZ Promotes Cell Proliferation and Epithelial-Mesenchymal Transition and Is Inhibited by the Hippo Pathway
- (2008) Q.-Y. Lei et al. MOLECULAR AND CELLULAR BIOLOGY
- The Hippo Pathway Promotes Notch Signaling in Regulation of Cell Differentiation, Proliferation, and Oocyte Polarity
- (2008) Jianzhong Yu et al. PLoS One
- Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses
- (2008) S. Jones et al. SCIENCE
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