- Home
- Publications
- Publication Search
- Publication Details
Title
Role of Transglutaminase 2 in Cell Death, Survival, and Fibrosis
Authors
Keywords
-
Journal
Cells
Volume 10, Issue 7, Pages 1842
Publisher
MDPI AG
Online
2021-07-21
DOI
10.3390/cells10071842
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Transglutaminase 2: a novel therapeutic target for idiopathic pulmonary fibrosis using selective small molecule inhibitors
- (2021) Shaun Fell et al. AMINO ACIDS
- Transglutaminase 2 Regulates Innate Immunity by Modulating the STING/TBK1/IRF3 Axis
- (2021) Luca Occhigrossi et al. JOURNAL OF IMMUNOLOGY
- Spatially Resolved Identification of Transglutaminase Substrates by Proteomics in Pulmonary Fibrosis
- (2021) Taishu Takeuchi et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Hypoxia-Dependent Expression of TG2 Isoforms in Neuroblastoma Cells as Consequence of Different MYCN Amplification Status
- (2020) Monica Currò et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- AFF1 inhibits adipogenic differentiation via targeting TGM2 transcription
- (2020) Yaqian Chen et al. CELL PROLIFERATION
- Celiac disease TG2 autoantibodies development: it takes two to tango
- (2020) Federica Rossin et al. Cell Death & Disease
- Transglutaminase 2 Depletion Attenuates α-Synuclein Mediated Toxicity in Mice
- (2020) Jie Zhang et al. NEUROSCIENCE
- Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation
- (2020) Akane S. Suzuki et al. Frontiers in Immunology
- Transglutaminase 2 as a novel target in chronic kidney disease – Methods, mechanisms and pharmacological inhibition
- (2020) Judit Prat-Duran et al. PHARMACOLOGY & THERAPEUTICS
- Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3
- (2019) Lorna A. Farrelly et al. NATURE
- Loss of transglutaminase 2 sensitizes for diet-induced obesity-related inflammation and insulin resistance due to enhanced macrophage c-Src signaling
- (2019) Tibor Sághy et al. Cell Death & Disease
- Extracellular Matrix Cross-Linking Enhances Fibroblast Growth and Protects against Matrix Proteolysis in Lung Fibrosis
- (2018) Christopher J. Philp et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Spotlight on the transglutaminase 2 gene: a focus on genomic and transcriptional aspects
- (2018) Nicoletta Bianchi et al. BIOCHEMICAL JOURNAL
- Transglutaminase type 2 in the regulation of proteostasis
- (2018) Manuela D’Eletto et al. BIOLOGICAL CHEMISTRY
- Transglutaminase 2: Friend or foe? The discordant role in neurons and astrocytes
- (2018) Breandan R. Quinn et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Non-alcoholic fatty liver disease severity is modulated by transglutaminase type 2
- (2018) Mauro Piacentini et al. Cell Death & Disease
- Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor
- (2018) Zhuo Wang et al. Cell Death & Disease
- Isozyme-specific comprehensive characterization of transglutaminase-crosslinked substrates in kidney fibrosis
- (2018) Hideki Tatsukawa et al. Scientific Reports
- Transglutaminase 2 programs differentiating acute promyelocytic leukemia cells in all-trans retinoic acid treatment to inflammatory stage through NF-kB activation
- (2018) Károly Jambrovics et al. HAEMATOLOGICA
- Biocatalysis by Transglutaminases: A Review of Biotechnological Applications
- (2018) Maria Savoca et al. Micromachines
- Optimised methods (SDS/PAGE and LC-MS) reveal deamidation in all examined transglutaminase-mediated reactions
- (2018) Éva Sivadó et al. FEBS Open Bio
- Microglia Endocytose Amyloid β Through the Binding of Transglutaminase 2 and Milk Fat Globule EGF Factor 8 Protein
- (2017) Kenji Kawabe et al. NEUROCHEMICAL RESEARCH
- Global identification and analysis of isozyme-specific possible substrates crosslinked by transglutaminases using substrate peptides in mouse liver fibrosis
- (2017) Hideki Tatsukawa et al. Scientific Reports
- Tissue transglutaminase (TG2) is involved in the resistance of cancer cells to the histone deacetylase (HDAC) inhibitor vorinostat
- (2016) Carmine Carbone et al. AMINO ACIDS
- Transcriptional control of transglutaminase 2 expression in mouse apoptotic thymocytes
- (2016) Katalin Sándor et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- A novel regulatory role for tissue transglutaminase in epithelial-mesenchymal transition in cystic fibrosis
- (2016) Samuel Nyabam et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Transglutaminase 2 has opposing roles in the regulation of cellular functions as well as cell growth and death
- (2016) H Tatsukawa et al. Cell Death & Disease
- Isopeptidase activity of human transglutaminase 2: disconnection from transamidation and characterization by kinetic parameters
- (2015) Róbert Király et al. AMINO ACIDS
- Physiological, pathological, and structural implications of non-enzymatic protein–protein interactions of the multifunctional human transglutaminase 2
- (2015) Kajal Kanchan et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Development of Potent and Selective Tissue Transglutaminase Inhibitors: Their Effect on TG2 Function and Application in Pathological Conditions
- (2015) Eduard Badarau et al. CHEMISTRY & BIOLOGY
- miR-19-Mediated Inhibition of Transglutaminase-2 Leads to Enhanced Invasion and Metastasis in Colorectal Cancer
- (2015) D. Cellura et al. MOLECULAR CANCER RESEARCH
- Tissue Transglutaminase, Not Lysyl Oxidase, Dominates Early Calcium-Dependent Remodeling of Fibroblast-Populated Collagen Lattices
- (2015) D.D. Simon et al. CELLS TISSUES ORGANS
- Acyl transfer mechanisms of tissue transglutaminase
- (2014) Jeffrey W. Keillor et al. BIOORGANIC CHEMISTRY
- Lack of transglutaminase 2 diminished T-cell responses in mice
- (2014) Jin-Hee Kim et al. IMMUNOLOGY
- Transglutaminase Regulation of Cell Function
- (2014) Richard L. Eckert et al. PHYSIOLOGICAL REVIEWS
- Inhibition of Transglutaminase 2, a Novel Target for Pulmonary Fibrosis, by Two Small Electrophilic Molecules
- (2013) Keith C. Olsen et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- TGM2 and implications for human disease: role of alternative splicing
- (2013) Charles Greenberg Frontiers in Bioscience-Landmark
- Syndecan-4 Knockout Leads to Reduced Extracellular Transglutaminase-2 and Protects against Tubulointerstitial Fibrosis
- (2013) A. Scarpellini et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Transglutaminase 2 modulates antigen-specific antibody response by suppressing Blimp-1 and AID expression of B cells in mice
- (2012) Jin-Hee Kim et al. IMMUNOLOGY LETTERS
- Transglutaminase 2 and Its Role in Pulmonary Fibrosis
- (2011) Keith C. Olsen et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Transglutaminase 2: A molecular Swiss army knife
- (2011) Soner Gundemir et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Induction of Cross-Linking and Silencing of Sp1 by Transglutaminase during Liver Injury in ASH and NASH via Different ER Stress Pathways
- (2011) Soichi Kojima et al. DIGESTIVE DISEASES
- Tissue Transglutaminase Does Not Affect Fibrotic Matrix Stability or Regression of Liver Fibrosis in Mice
- (2011) Yury Popov et al. GASTROENTEROLOGY
- Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease
- (2011) Lise Munsie et al. HUMAN MOLECULAR GENETICS
- Interleukin-6 Protects Human Macrophages from Cellular Cholesterol Accumulation and Attenuates the Proinflammatory Response
- (2011) Eric Frisdal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of Extracellular Transglutaminase 2 by Thioredoxin
- (2011) Xi Jin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Free fatty acids induce transglutaminase 2-dependent apoptosis in hepatocytes via ER stress-stimulated PERK pathways
- (2011) Ting-Fang Kuo et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice
- (2011) Keunhee Oh et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cytokines regulate neuronal gene expression: Differential effects of Th1, Th2 and monocyte/macrophage cytokines
- (2011) Robert P. Lisak et al. JOURNAL OF NEUROIMMUNOLOGY
- Dual induction of caspase 3- and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells
- (2011) Hideki Tatsukawa et al. Molecular Cancer
- Targeting Ovarian Tumor Cell Adhesion Mediated by Tissue Transglutaminase
- (2011) M. Khanna et al. MOLECULAR CANCER THERAPEUTICS
- Myeloid-specific estrogen receptor deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development
- (2011) V. Ribas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Brain infarction correlates more closely with acrolein than with reactive oxygen species
- (2010) Ryotaro Saiki et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Transglutaminase 2: A multi-tasking protein in the complex circuitry of inflammation and cancer
- (2010) Kapil Mehta et al. BIOCHEMICAL PHARMACOLOGY
- Decreased S -Nitrosylation of Tissue Transglutaminase Contributes to Age-Related Increases in Vascular Stiffness
- (2010) Lakshmi Santhanam et al. CIRCULATION RESEARCH
- Déjà vuwith a twist: transglutaminases in bioenergetics and transcriptional dysfunction in Huntington's disease
- (2010) Parsa Kazemi-Esfarjani et al. EMBO Molecular Medicine
- Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease
- (2010) Stephen J. McConoughey et al. EMBO Molecular Medicine
- Importance of syndecan-4 and syndecan -2 in osteoblast cell adhesion and survival mediated by a tissue transglutaminase−fibronectin complex
- (2010) Z. Wang et al. EXPERIMENTAL CELL RESEARCH
- RGD-independent Cell Adhesion via a Tissue Transglutaminase-Fibronectin Matrix Promotes Fibronectin Fibril Deposition and Requires Syndecan-4/2 and α5β1 Integrin Co-signaling
- (2010) Zhuo Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MTA1 Coregulation of Transglutaminase 2 Expression and Function during Inflammatory Response
- (2010) Krishna Sumanth Ghanta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Redox Regulation of Transglutaminase 2 Activity
- (2010) Jorunn Stamnaes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
- (2010) Alessandro Luciani et al. NATURE CELL BIOLOGY
- Transglutaminase 2 protects against ischemic stroke
- (2010) A.J. Filiano et al. NEUROBIOLOGY OF DISEASE
- Transglutaminase 2 expression induced by lipopolysaccharide stimulation together with NO synthase induction in cultured astrocytes
- (2010) K. Takano et al. NEUROCHEMISTRY INTERNATIONAL
- Human tissue transglutaminase is inhibited by pharmacologic and chemical acetylation
- (2010) Thung S. Lai et al. PROTEIN SCIENCE
- Expression of tissue-type transglutaminase (tTG) and the effect of tTG inhibitor on the hippocampal CA1 region after transient ischemia in gerbils
- (2009) In Koo Hwang et al. BRAIN RESEARCH
- The adenine nucleotide translocator 1 acts as a type 2 transglutaminase substrate: implications for mitochondrial-dependent apoptosis
- (2009) W Malorni et al. CELL DEATH AND DIFFERENTIATION
- Transglutaminases in inflammation and fibrosis of the gastrointestinal tract and the liver
- (2009) L. Elli et al. DIGESTIVE AND LIVER DISEASE
- Garlic extract prevents CCl4-induced liver fibrosis in rats: The role of tissue transglutaminase
- (2009) Giuseppe D’Argenio et al. DIGESTIVE AND LIVER DISEASE
- Increase in transglutaminase 2 expression is associated with NF-kappaB activation in breast cancer tissues
- (2009) Kang-Seo Park Frontiers in Bioscience-Landmark
- Role of Transglutaminase 2 in Liver Injury via Cross-linking and Silencing of Transcription Factor Sp1
- (2009) Hideki Tatsukawa et al. GASTROENTEROLOGY
- Transglutaminase 2 is expressed and active on the surface of human monocyte-derived dendritic cells and macrophages
- (2009) Judit Hodrea et al. IMMUNOLOGY LETTERS
- Increased TG2 Expression Can Result in Induction of Transforming Growth Factor β1, Causing Increased Synthesis and Deposition of Matrix Proteins, Which Can Be Regulated by Nitric Oxide
- (2009) Dilek Telci et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SUMOylation of Tissue Transglutaminase as Link between Oxidative Stress and Inflammation
- (2009) A. Luciani et al. JOURNAL OF IMMUNOLOGY
- Transglutaminase 2 Is Needed for the Formation of an Efficient Phagocyte Portal in Macrophages Engulfing Apoptotic Cells
- (2009) B. Toth et al. JOURNAL OF IMMUNOLOGY
- Transglutaminases and neurodegeneration
- (2009) Thomas M. Jeitner et al. JOURNAL OF NEUROCHEMISTRY
- Transglutaminase 2 suppresses apoptosis by modulating caspase 3 and NF-κB activity in hypoxic tumor cells
- (2009) G -Y Jang et al. ONCOGENE
- Transglutaminases and Disease: Lessons From Genetically Engineered Mouse Models and Inherited Disorders
- (2009) Siiri E. Iismaa et al. PHYSIOLOGICAL REVIEWS
- Intracellular Localization and Conformational State of Transglutaminase 2: Implications for Cell Death
- (2009) Soner Gundemir et al. PLoS One
- Tissue Transglutaminase Contributes to Interstitial Renal Fibrosis by Favoring Accumulation of Fibrillar Collagen through TGF-β Activation and Cell Infiltration
- (2008) Nasim Shweke et al. AMERICAN JOURNAL OF PATHOLOGY
- Transglutaminase 2 cross-linking of matrix proteins: biological significance and medical applications
- (2008) R. J. Collighan et al. AMINO ACIDS
- Homocysteine-induced toxicity increases TG2 expression in Neuro2a cells
- (2008) M. Currò et al. AMINO ACIDS
- The propensity for deamidation and transamidation of peptides by transglutaminase 2 is dependent on substrate affinity and reaction conditions
- (2008) Jorunn Stamnaes et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Transglutaminase 2 protects against ischemic insult, interacts with HIF1β, and attenuates HIF1 signaling
- (2008) Anthony J. Filiano et al. FASEB JOURNAL
- Fibronectin-Tissue Transglutaminase Matrix Rescues RGD-impaired Cell Adhesion through Syndecan-4 and β1Integrin Co-signaling
- (2008) Dilek Telci et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NF-κB-activated tissue transglutaminase is involved in ethanol-induced hepatic injury and the possible role of propolis in preventing fibrogenesis
- (2008) Ching-Shyang Chen et al. TOXICOLOGY
- Tissue transglutaminase catalyzes the deamidation of glutamines in lens βB2- and βB3-crystallins
- (2007) Sandor Boros et al. EXPERIMENTAL EYE RESEARCH
- Effect of growth factors and steroids on transglutaminase activity and expression in primary astroglial cell cultures
- (2007) A. Campisi et al. JOURNAL OF NEUROSCIENCE RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More