Manipulation of Cellular Processes via Nucleolus Hijaking in the Course of Viral Infection in Mammals

Valency and Binding Affinity Variations Can Regulate the Multilayered Organization of Protein Condensates with Many Components

(2021) Ignacio Sanchez-Burgos et al.   Biomolecules

Regulation of biomolecular condensate dynamics by signaling

(2021) Carla Garcia-Cabau et al.   CURRENT OPINION IN CELL BIOLOGY

Treacle and TOPBP1 control replication stress response in the nucleolus

(2021) Artem K. Velichko et al.   JOURNAL OF CELL BIOLOGY

A Guide to Regulation of the Formation of Biomolecular Condensates

(2020) Anna Bratek‐Skicki et al.   FEBS Journal

Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation

(2020) Clémence Mooser et al.   Nature Communications

Composition-dependent thermodynamics of intracellular phase separation

(2020) Joshua A. Riback et al.   NATURE

Nucleolar protein NOP2/NSUN1 suppresses HIV-1 transcription and promotes viral latency by competing with Tat for TAR binding and methylation

(2020) Weili Kong et al.   PLoS Pathogens

Mapping the nucleolar proteome reveals a spatiotemporal organization related to intrinsic protein disorder

(2020) Lovisa Stenström et al.   Molecular Systems Biology

The nucleolus as a multiphase liquid condensate

(2020) Denis L. J. Lafontaine et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

mTOR: A Cellular Regulator Interface in Health and Disease

(2019) Fahd Boutouja et al.   Cells

The multiple mechanisms that regulate p53 activity and cell fate

(2019) Antonina Hafner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular mechanistic insight of hepatitis B virus mediated hepatocellular carcinoma

(2019) Vivek K. Chaturvedi et al.   MICROBIAL PATHOGENESIS

Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription

(2019) Artem K Velichko et al.   NUCLEIC ACIDS RESEARCH

Phase-to-Phase With Nucleoli – Stress Responses, Protein Aggregation and Novel Roles of RNA

(2019) Leena Latonen   Frontiers in Cellular Neuroscience

The nucleolus: a central response hub for the stressors that drive cancer progression

(2019) Shannon E. Weeks et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Formation of adenovirus DNA replication compartments and viral DNA accumulation sites by host chromatin regulatory proteins including NPM1

(2019) Michelle Jane Genoveso et al.   FEBS Journal

Long Noncoding RNAs and Stress Response in the Nucleolus

(2019) Sergei A. Pirogov et al.   Cells

Nucleolus: A Central Hub for Nuclear Functions

(2019) Olga V. Iarovaia et al.   TRENDS IN CELL BIOLOGY

The Role of Post-Translational Modifications in the Phase Transitions of Intrinsically Disordered Proteins

(2019) Izzy Owen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ribosomal DNA and the Nucleolus as Keystones of Nuclear Architecture, Organization, and Function

(2019) Amanda V. Cerqueira et al.   TRENDS IN GENETICS

Nucleolar Sequestration: Remodeling Nucleoli Into Amyloid Bodies

(2019) Miling Wang et al.   Frontiers in Genetics

Mechanisms for Active Regulation of Biomolecular Condensates

(2019) Johannes Söding et al.   TRENDS IN CELL BIOLOGY

Ribosome biogenesis restricts innate immune responses to virus infection and DNA

(2019) Christopher Bianco et al.   eLife

Dynamic regulation of nucleolar architecture

(2018) Attila Németh et al.   CURRENT OPINION IN CELL BIOLOGY

lncRNA PAPAS tethered to the rDNA enhancer recruits hypophosphorylated CHD4/NuRD to repress rRNA synthesis at elevated temperatures

(2018) Zhongliang Zhao et al.   GENES & DEVELOPMENT

Identification of small non-coding RNA classes expressed in swine whole blood during HP-PRRSV infection

(2018) Damarius S. Fleming et al.   VIROLOGY

Role of HBx in hepatitis B virus persistence and its therapeutic implications

(2018) Betty L Slagle et al.   Current Opinion in Virology

Ribosomal biogenesis as an emerging target of neurodevelopmental pathologies

(2018) Michal Hetman et al.   JOURNAL OF NEUROCHEMISTRY

The nucleolar protein LYAR facilitates ribonucleoprotein assembly of influenza A virus

(2018) Cha Yang et al.   JOURNAL OF VIROLOGY

p21Waf1/Cip1: its paradoxical effect in the regulation of breast cancer

(2018) Samir F. Zohny et al.   Breast Cancer

Viral regulation of host cell biology by hijacking of the nucleolar DNA-damage response

(2018) Stephen M. Rawlinson et al.   Nature Communications

Breaking Bad: How Viruses Subvert the Cell Cycle

(2018) Ying Fan et al.   Frontiers in Cellular and Infection Microbiology

Identifying Host Factors Associated with DNA Replicated During Virus Infection

(2017) Emigdio D. Reyes et al.   MOLECULAR & CELLULAR PROTEOMICS

Kinetics of the association of dengue virus capsid protein with the granular component of nucleolus

(2017) Ashish Kumar Tiwary et al.   VIROLOGY

The nucleolar helicase DDX56 redistributes to West Nile virus assembly sites

(2017) Colleen R. Reid et al.   VIROLOGY

The interaction between NOLC1 and IAV NS1 protein promotes host cell apoptosis and reduces virus replication

(2017) Chunyu Zhu et al.   Oncotarget

Ribosomal stress and Tp53-mediated neuronal apoptosis in response to capsid protein of the Zika virus

(2017) Lukasz P. Slomnicki et al.   Scientific Reports

Nucleocapsid Interacts with NPM1 and Protects it from Proteolytic Cleavage, Enhancing Cell Survival and is Involved in PEDV Growth

(2017) Da Shi et al.   Scientific Reports

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Multiple functions of p21 in cell cycle, apoptosis and transcriptional regulation after DNA damage

(2016) Ansar Karimian et al.   DNA REPAIR

Nonstructural Protein NSs of Schmallenberg Virus Is Targeted to the Nucleolus and Induces Nucleolar Disorganization

(2016) Julie Gouzil et al.   JOURNAL OF VIROLOGY

Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export

(2016) Ryan T. Behrens et al.   JOURNAL OF VIROLOGY

Structural basis of an essential interaction between influenza polymerase and Pol II CTD

(2016) Maria Lukarska et al.   NATURE

An updated human snoRNAome

(2016) Hadi Jorjani et al.   NUCLEIC ACIDS RESEARCH

Assembly and trafficking of box C/D and H/ACA snoRNPs

(2016) Séverine Massenet et al.   RNA Biology

Nucleolin promotes in vitro translation of feline calicivirus genomic RNA

(2016) Beatriz Alvarado Hernández et al.   VIROLOGY

A redox mechanism underlying nucleolar stress sensing by nucleophosmin

(2016) Kai Yang et al.   Nature Communications

Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA

(2016) Diana M Mitrea et al.   eLife

Properties and Functions of the Dengue Virus Capsid Protein

(2016) Laura A. Byk et al.   Annual Review of Virology

Nucleolin interacts with influenza A nucleoprotein and contributes to viral ribonucleoprotein complexes nuclear trafficking and efficient influenza viral replication

(2016) Olivier Terrier et al.   Scientific Reports

The role of DNA damage responses in p53 biology

(2015) Daniel Speidel   ARCHIVES OF TOXICOLOGY

The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy

(2015) Simone J. Woods et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The HBx oncoprotein of hepatitis B virus engages nucleophosmin to promote rDNA transcription and cellular proliferation

(2015) Richa Ahuja et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The nucleolar interface of RNA viruses

(2015) Stephen M. Rawlinson et al.   CELLULAR MICROBIOLOGY

A retrovirus packages nascent host noncoding RNAs from a novel surveillance pathway

(2015) Matthew J. Eckwahl et al.   GENES & DEVELOPMENT

Cytosolic Accumulation of Small Nucleolar RNAs (snoRNAs) Is Dynamically Regulated by NADPH Oxidase

(2015) Christopher L. Holley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Nucleolar Protein, Ribosomal RNA Processing 1 Homolog B (RRP1B), Enhances the Recruitment of Cellular mRNA in Influenza Virus Transcription

(2015) Wen-Chi Su et al.   JOURNAL OF VIROLOGY

Sequencing the cap-snatching repertoire of H1N1 influenza provides insight into the mechanism of viral transcription initiation

(2015) David Koppstein et al.   NUCLEIC ACIDS RESEARCH

Influenza A virus preferentially snatches noncoding RNA caps

(2015) Weifeng Gu et al.   RNA

Principles of protein targeting to the nucleolus

(2015) Robert M Martin et al.   Nucleus

Principles of protein targeting to the nucleolus

(2015) Robert M Martin et al.   Nucleus

Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11

(2015) Kazem Nouri et al.   PLoS One

Viruses and the nucleolus: The fatal attraction

(2014) Anna Salvetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

HIV-1 Rev Multimerization: Mechanism and Insights

(2014) Thomas Vercruysse et al.   CURRENT HIV RESEARCH

Viral and cellular subnuclear structures in human cytomegalovirus-infected cells

(2014) B. L. Strang   JOURNAL OF GENERAL VIROLOGY

Dynamic and Nucleolin-Dependent Localization of Human Cytomegalovirus UL84 to the Periphery of Viral Replication Compartments and Nucleoli

(2014) B. J. Bender et al.   JOURNAL OF VIROLOGY

A Role for H/ACA and C/D Small Nucleolar RNAs in Viral Replication

(2014) James L. Murray et al.   MOLECULAR BIOTECHNOLOGY

VirusMentha: a new resource for virus-host protein interactions

(2014) Alberto Calderone et al.   NUCLEIC ACIDS RESEARCH

VirHostNet 2.0: surfing on the web of virus/host molecular interactions data

(2014) Thibaut Guirimand et al.   NUCLEIC ACIDS RESEARCH

Human Papillomavirus 16 Oncoprotein E7 Stimulates UBF1-Mediated rDNA Gene Transcription, Inhibiting a p53-Independent Activity of p14ARF

(2014) Isabelle Dichamp et al.   PLoS One

The Coronavirus Nucleocapsid Is a Multifunctional Protein

(2014) Ruth McBride et al.   Viruses-Basel

DNA Virus Replication Compartments

(2013) M. Schmid et al.   JOURNAL OF VIROLOGY

Nucleolin Interacts with the Dengue Virus Capsid Protein and Plays a Role in Formation of Infectious Virus Particles

(2013) C. A. Balinsky et al.   JOURNAL OF VIROLOGY

Widespread Long Noncoding RNAs as Endogenous Target Mimics for MicroRNAs in Plants

(2013) H.-J. Wu et al.   PLANT PHYSIOLOGY

Combined miRNA and mRNA Signature Identifies Key Molecular Players and Pathways Involved in Chikungunya Virus Infection in Human Cells

(2013) Tanvi Saxena et al.   PLoS One

HIV-1 Gag co-opts a cellular complex containing DDX6, a helicase that facilitates capsid assembly

(2012) Jonathan C. Reed et al.   JOURNAL OF CELL BIOLOGY

The nucleolus and herpesviral usurpation

(2012) L. Ni et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Nucleolar Protein Trafficking in Response to HIV-1 Tat: Rewiring the Nucleolus

(2012) Mohamed Ali Jarboui et al.   PLoS One

Host Cell Nucleolin Is Required To Maintain the Architecture of Human Cytomegalovirus Replication Compartments

(2012) B. L. Strang et al.   mBio

The nucleolus directly regulates p53 export and degradation

(2011) Mark T. Boyd et al.   JOURNAL OF CELL BIOLOGY

The HBx protein of hepatitis B virus regulates the expression, intracellular distribution and functions of ribosomal protein S27a

(2011) G. Fatima et al.   JOURNAL OF GENERAL VIROLOGY

The Capsid-Binding Nucleolar Helicase DDX56 Is Important for Infectivity of West Nile Virus

(2011) Z. Xu et al.   JOURNAL OF VIROLOGY

Alphavirus M1 induces apoptosis of malignant glioma cells via downregulation and nucleolar translocation of p21WAF1/CIP1 protein

(2010) Jun Hu et al.   CELL CYCLE

Cell-cycle-dependent localization of human cytomegalovirus UL83 phosphoprotein in the nucleolus and modulation of viral gene expression in human embryo fibroblasts in vitro

(2010) Maria-Cristina Arcangeletti et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

To kill or be killed: how viruses interact with the cell death machinery

(2010) V. Kaminskyy et al.   JOURNAL OF INTERNAL MEDICINE

Quantitative Proteomics Using SILAC Coupled to LC−MS/MS Reveals Changes in the Nucleolar Proteome in Influenza A Virus-Infected Cells

(2010) Edward Emmott et al.   JOURNAL OF PROTEOME RESEARCH

The Nucleolus under Stress

(2010) Séverine Boulon et al.   MOLECULAR CELL

Characterization and prediction of protein nucleolar localization sequences

(2010) Michelle S. Scott et al.   NUCLEIC ACIDS RESEARCH

A viral assembly factor promotes AAV2 capsid formation in the nucleolus

(2010) F. Sonntag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleolar proteomics and viral infection

(2010) Julian A. Hiscox et al.   PROTEOMICS

The Nucleolus

(2010) T. Pederson   Cold Spring Harbor Perspectives in Biology

The nucleolus and viral infection

(2010) Lei Wang et al.   VIROLOGICA SINICA

Activation of Ribosomal RNA Transcription by Hepatitis C Virus Involves Upstream Binding Factor Phosphorylation via Induction of Cyclin D1

(2009) S. Raychaudhuri et al.   CANCER RESEARCH

Nucleolar targeting: the hub of the matter

(2009) Edward Emmott et al.   EMBO REPORTS

In search of nonribosomal nucleolar protein function and regulation

(2009) Thoru Pederson et al.   JOURNAL OF CELL BIOLOGY

GLTSCR2/PICT-1, a Putative Tumor Suppressor Gene Product, Induces the Nucleolar Targeting of the Kaposi's Sarcoma-Associated Herpesvirus KS-Bcl-2 Protein

(2009) I. Kalt et al.   JOURNAL OF VIROLOGY

Nucleolin Associates with the Human Cytomegalovirus DNA Polymerase Accessory Subunit UL44 and Is Necessary for Efficient Viral Replication

(2009) B. L. Strang et al.   JOURNAL OF VIROLOGY

Proteomics Analysis of the Nucleolus in Adenovirus-infected Cells

(2009) Yun W. Lam et al.   MOLECULAR & CELLULAR PROTEOMICS

AMP-activated protein kinase adapts rRNA synthesis to cellular energy supply

(2009) S. Hoppe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uncoupling ribosome biogenesis regulation from RNA polymerase I activity during herpes simplex virus type 1 infection

(2009) S. Belin et al.   RNA

Enhancement of Adeno-Associated Virus Infection by Mobilizing Capsids into and Out of the Nucleolus

(2008) J. S. Johnson et al.   JOURNAL OF VIROLOGY

Nucleolin Is Required for an Efficient Herpes Simplex Virus Type 1 Infection

(2008) A. Calle et al.   JOURNAL OF VIROLOGY