HGF/c-Met Inhibition as Adjuvant Therapy Improves Outcomes in an Orthotopic Mouse Model of Pancreatic Cancer

Pancreatic stellate cells: Aiding and abetting pancreatic cancer progression

(2020) Srinivasa P. Pothula et al.   PANCREATOLOGY

Targeting the HGF/c-MET pathway in advanced pancreatic cancer: a key element of treatment that limits primary tumour growth and eliminates metastasis

(2020) Zhihong Xu et al.   BRITISH JOURNAL OF CANCER

An Orthotopic Resectional Mouse Model of Pancreatic Cancer

(2020) Tony C. Y. Pang et al.   Jove-Journal of Visualized Experiments

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

The reactome pathway knowledgebase

(2019) Bijay Jassal et al.   NUCLEIC ACIDS RESEARCH

Insulin/IGF-driven cancer cell-stroma crosstalk as a novel therapeutic target in pancreatic cancer

(2018) Ayse Ceren Mutgan et al.   Molecular Cancer

PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools

(2018) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Derivation and Validation of the Potential Core Genes in Pancreatic Cancer for Tumor-Stroma Crosstalk

(2018) Ran Xue et al.   Biomed Research International

Rilotumumab plus epirubicin, cisplatin, and capecitabine as first-line therapy in advanced MET-positive gastric or gastro-oesophageal junction cancer (RILOMET-1): a randomised, double-blind, placebo-controlled, phase 3 trial

(2017) Daniel V T Catenacci et al.   LANCET ONCOLOGY

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

Targeting the HGF/c-MET pathway: stromal remodelling in pancreatic cancer

(2017) Srinivasa P. Pothula et al.   Oncotarget

Circulating Tumor Cell Phenotype Predicts Recurrence and Survival in Pancreatic Adenocarcinoma

(2016) Katherine E. Poruk et al.   ANNALS OF SURGERY

Hepatocyte growth factor inhibition: a novel therapeutic approach in pancreatic cancer

(2016) Srinivasa P Pothula et al.   BRITISH JOURNAL OF CANCER

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability

(2016) D. R. Pattabiraman et al.   SCIENCE

Pancreatic Fibroblasts Stimulate the Motility of Pancreatic Cancer Cells through IGF1/IGF1R Signaling under Hypoxia

(2016) Toshiki Hirakawa et al.   PLoS One

Multi-Phenotypic subtyping of circulating tumor cells using sequential fluorescent quenching and restaining

(2016) Daniel L Adams et al.   Scientific Reports

A randomized, double-blind, placebo-controlled, phase III trial of erlotinib with or without a c-Met inhibitor tivantinib (ARQ 197) in Asian patients with previously treated stage IIIB/IV nonsquamous nonsmall-cell lung cancer harboring wild-type epidermal growth factor receptor (ATTENTION study)

(2015) H. Yoshioka et al.   ANNALS OF ONCOLOGY

Conditionally immortalized human pancreatic stellate cell lines demonstrate enhanced proliferation and migration in response to IGF-I

(2015) Ann H. Rosendahl et al.   EXPERIMENTAL CELL RESEARCH

Phase III Multinational, Randomized, Double-Blind, Placebo-Controlled Study of Tivantinib (ARQ 197) Plus Erlotinib Versus Erlotinib Alone in Previously Treated Patients With Locally Advanced or Metastatic Nonsquamous Non–Small-Cell Lung Cancer

(2015) Giorgio Scagliotti et al.   JOURNAL OF CLINICAL ONCOLOGY

The prognostic value of stroma in pancreatic cancer in patients receiving adjuvant therapy

(2015) Katherine M. Bever et al.   HPB

The prognostic role of desmoplastic stroma in pancreatic ductal adenocarcinoma

(2015) Lai Mun Wang et al.   Oncotarget

Receptor for Hyaluronic Acid-Mediated Motility is Associated with Poor Survival in Pancreatic Ductal Adenocarcinoma

(2015) Xiao-Bo Cheng et al.   Journal of Cancer

Comparison of the transcriptional landscapes between human and mouse tissues

(2014) Shin Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells

(2014) David T. Ting et al.   Cell Reports

Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition

(2012) Tobias M Gorges et al.   BMC CANCER

Epidermal growth factor receptor and insulinlike growth factor 1 receptor expression predict poor survival in pancreatic ductal adenocarcinoma

(2011) Matias E. Valsecchi et al.   CANCER

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis

(2010) Zhihong Xu et al.   AMERICAN JOURNAL OF PATHOLOGY

Malignant cells facilitate lung metastasis by bringing their own soil

(2010) D. G. Duda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pancreatic Stellate Cells: Partners in Crime with Pancreatic Cancer Cells

(2008) A. Vonlaufen et al.   CANCER RESEARCH

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

(2008) R. F. Hwang et al.   CANCER RESEARCH