Pancreatic Fibroblasts Stimulate the Motility of Pancreatic Cancer Cells through IGF1/IGF1R Signaling under Hypoxia

IGF-1 receptor and IGF binding protein-3 might predict prognosis of patients with resectable pancreatic cancer

(2013) Toshiki Hirakawa et al.   BMC CANCER

Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer

(2013) A. Spreafico et al.   CLINICAL CANCER RESEARCH

New insights into pancreatic cancer biology

(2012) M. Hidalgo   ANNALS OF ONCOLOGY

Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells

(2012) Shin Hamada et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Clinical Effect of the Dual-Targeting Strategy Involving PI3K/AKT/mTOR and RAS/MEK/ERK Pathways in Patients with Advanced Cancer

(2012) T. Shimizu et al.   CLINICAL CANCER RESEARCH

Targeting the Cancer-Stroma Interaction: A Potential Approach for Pancreatic Cancer Treatment

(2012) Xuqi Li et al.   CURRENT PHARMACEUTICAL DESIGN

K-RAS Mutant Pancreatic Tumors Show Higher Sensitivity to MEK than to PI3K Inhibition In Vivo

(2012) Irmgard Hofmann et al.   PLoS One

VEGF-A/VEGFR-2 Signaling Plays an Important Role for the Motility of Pancreas Cancer Cells

(2011) Yosuke Doi et al.   ANNALS OF SURGICAL ONCOLOGY

Upregulation of cancer-associated myofibroblasts by TGF-β from scirrhous gastric carcinoma cells

(2011) Y Fuyuhiro et al.   BRITISH JOURNAL OF CANCER

Molecular Targeted Approaches for Treatment of Pancreatic Cancer

(2011) Z.Q. Huang et al.   CURRENT PHARMACEUTICAL DESIGN

StellaTUM: current consensus and discussion on pancreatic stellate cell research

(2011) Mert Erkan et al.   GUT

Hepatic stellate cells: Partners in crime for liver metastases?

(2011) Ningling Kang et al.   HEPATOLOGY

HER3 Overexpression as an Independent Indicator of Poor Prognosis for Patients with Curatively Resected Pancreatic Cancer

(2011) Toshiki Hirakawa et al.   ONCOLOGY

Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis

(2010) Zhihong Xu et al.   AMERICAN JOURNAL OF PATHOLOGY

Pancreatic stellate cells promote epithelial-mesenchymal transition in pancreatic cancer cells

(2010) Kazuhiro Kikuta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Expression of a Hypoxia-Associated Protein, Carbonic Anhydrase-9, Correlates with Malignant Phenotypes of Gastric Carcinoma

(2010) Yukihiro Kato et al.   DIGESTION

A Review of the Most Promising Biomarkers in Colorectal Cancer: One Step Closer to Targeted Therapy

(2010) V. Deschoolmeester et al.   ONCOLOGIST

HER2 overexpression correlates with survival after curative resection of pancreatic cancer

(2009) Masahiro Komoto et al.   CANCER SCIENCE

In vitroandin vivoevidence that a combination of lapatinib plus S-1 is a promising treatment for pancreatic cancer

(2009) Masahiro Komoto et al.   CANCER SCIENCE

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

(2008) R. F. Hwang et al.   CANCER RESEARCH

Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c-Met system via hypoxia inducible factor-1 in pancreatic cancer

(2008) Yoshihiko Kitajima et al.   CANCER SCIENCE