Genetic Susceptibility to Acute Kidney Injury

Current research status of HLA in immune‐related diseases

(2021) Bingnan Liu et al.   Immunity Inflammation and Disease

The Macrophage Migration Inhibitory Factor (MIF) Promoter Polymorphisms (rs3063368, rs755622) Predict Acute Kidney Injury and Death after Cardiac Surgery

(2020) Luisa Averdunk et al.   Journal of Clinical Medicine

Genome-wide association study of myocardial infarction, atrial fibrillation, acute stroke, acute kidney injury and delirium after cardiac surgery – a sub-analysis of the RIPHeart-Study

(2019) Sabine Westphal et al.   BMC Cardiovascular Disorders

Macrophage migration inhibitory factor promotes renal injury induced by ischemic reperfusion

(2019) Jin H Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Benefits and limitations of genome-wide association studies

(2019) Vivian Tam et al.   NATURE REVIEWS GENETICS

Common Inflammation-Related Candidate Gene Variants and Acute Kidney Injury in 2647 Critically Ill Finnish Patients

(2019) Laura M. Vilander et al.   Journal of Clinical Medicine

NFκB and Kidney Injury

(2019) Ning Song et al.   Frontiers in Immunology

Acute kidney injury

(2019) Claudio Ronco et al.   LANCET

Perioperative Acute Kidney Injury

(2019) Sam D. Gumbert et al.   ANESTHESIOLOGY

Preliminary Report on the Association Between STAT3 Polymorphisms and Susceptibility to Acute Kidney Injury After Cardiopulmonary Bypass

(2018) Sara Aghakhani Chegeni et al.   BIOCHEMICAL GENETICS

Genetic variants and acute kidney injury: A review of the literature

(2018) Daniel B. Larach et al.   JOURNAL OF CRITICAL CARE

Antithrombin Ⅲ is a Novel Predictor for Contrast Induced Nephropathy After Coronary Angiography

(2018) Rui Wu et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Assessment of tumor necrosis factor alpha polymorphism TNF-α−238 (rs 361525) as a risk factor for development of acute kidney injury in critically ill patients

(2018) Sameer H. Fatani et al.   MOLECULAR BIOLOGY REPORTS

The protective role of macrophage migration inhibitory factor in acute kidney injury after cardiac surgery

(2018) Christian Stoppe et al.   Science Translational Medicine

Antithrombin III Attenuates AKI Following Acute Severe Pancreatitis

(2018) Yiwei Kong et al.   SHOCK

Association between inflammatory-response gene polymorphisms and risk of acute kidney injury in children

(2018) Jing He et al.   BIOSCIENCE REPORTS

Postoperative kidney oxygen saturation as a novel marker for acute kidney injury after adult cardiac surgery

(2018) Christian Ortega-Loubon et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Role of microRNA in the detection, progression, and intervention of acute kidney injury

(2017) Yan-Fang Zou et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Surfactant protein-D (SP-D) gene polymorphisms and serum level as predictors of susceptibility and prognosis of acute kidney injury in the Chinese population

(2017) Jiao Liu et al.   BMC Nephrology

Molecular differences in susceptibility of the kidney to sepsis-induced kidney injury

(2017) Martin Matejovic et al.   BMC Nephrology

Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis

(2017) Florence L. Johnson et al.   Journal of the American Heart Association

Interleukin-6 Signaling Pathway and Its Role in Kidney Disease: An Update

(2017) Hua Su et al.   Frontiers in Immunology

Acute kidney injury burden in different clinical units: Data from nationwide survey in China

(2017) Xiaojing Tang et al.   PLoS One

Diseases due to unhealthy environments: an updated estimate of the global burden of disease attributable to environmental determinants of health

(2016) A. Prüss-Ustün et al.   JOURNAL OF PUBLIC HEALTH

Study of the role of tumor necrosis factor-α (–308 G/A) and interleukin-10 (–1082 G/A) polymorphisms as potential risk factors to acute kidney injury in patients with severe sepsis using high-resolution melting curve analysis

(2016) Doaa I. Hashad et al.   RENAL FAILURE

Manganese superoxide dismutase, glutathione peroxidase and catalase gene polymorphisms and clinical outcomes in acute kidney injury

(2016) Veysel Kidir et al.   RENAL FAILURE

Inhibition of PHLPP2/cyclin D1 protein translation contributes to the tumor suppressive effect of NFκB2 (p100)

(2016) Jiawei Xu et al.   Oncotarget

Disentangling genetic and environmental risk factors for individual diseases from multiplex comorbidity networks

(2016) Peter Klimek et al.   Scientific Reports

Functional and Structural Consequence of Rare Exonic Single Nucleotide Polymorphisms: One Story, Two Tales

(2015) Wanjun Gu et al.   Genome Biology and Evolution

Innate immunity of surfactant proteins A and D in urinary tract infection with uropathogenic Escherichia coli

(2015) Fengqi Hu et al.   Innate Immunity

Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study

(2015) Eric A. J. Hoste et al.   INTENSIVE CARE MEDICINE

Plasma IL-6 and IL-10 Concentrations Predict AKI and Long-Term Mortality in Adults after Cardiac Surgery

(2015) W. R. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci

(2015) Mark Stafford-Smith et al.   KIDNEY INTERNATIONAL

Antithrombin III/SerpinC1 insufficiency exacerbates renal ischemia/reperfusion injury

(2015) Feng Wang et al.   KIDNEY INTERNATIONAL

APOL1nephropathy: from gene to mechanisms of kidney injury

(2015) Etty Kruzel-Davila et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Interleukin-6 and interleukin-10 as acute kidney injury biomarkers in pediatric cardiac surgery

(2015) Jason H. Greenberg et al.   PEDIATRIC NEPHROLOGY

A Pilot Study Identifying a Set of microRNAs As Precise Diagnostic Biomarkers of Acute Kidney Injury

(2015) Elia Aguado-Fraile et al.   PLoS One

Genetic predisposition to acute kidney injury – a systematic review

(2015) Laura M. Vilander et al.   BMC Nephrology

NF-κB in inflammation and renal diseases

(2015) Haisong Zhang et al.   Cell and Bioscience

Pilot study of association of catechol-O-methyl transferase rs4680 genotypes with acute kidney injury and tubular stress after open heart surgery

(2014) Christian Albert et al.   Biomarkers in Medicine

Adiponectin and Functional Adiponectin Receptor 1 Are Expressed by Airway Epithelial Cells in Chronic Obstructive Pulmonary Disease

(2014) M. Miller et al.   JOURNAL OF IMMUNOLOGY

Urine interleukin-18 in prediction of acute kidney injury: a systemic review and meta-analysis

(2014) Xin Lin et al.   JOURNAL OF NEPHROLOGY

Frequency of TGF-βand IFN-γGenotype as Risk Factors for Acute Kidney Injury and Death in Intensive Care Unit Patients

(2014) Caren Cristina Grabulosa et al.   Biomed Research International

Lifetime Incidence of CKD Stages 3-5 in the United States

(2013) Morgan E. Grams et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Gene Polymorphisms of Interleukin-10 and Tumor Necrosis Factor-α Are Associated with Contrast-Induced Nephropathy

(2013) Chao-Fu Chang et al.   AMERICAN JOURNAL OF NEPHROLOGY

miR-205 Targets PTEN and PHLPP2 to Augment AKT Signaling and Drive Malignant Phenotypes in Non-Small Cell Lung Cancer

(2013) J. Cai et al.   CANCER RESEARCH

Tumour necrosis factor-α plus interleukin-10 low producer phenotype predicts acute kidney injury and death in intensive care unit patients

(2013) M. A. Dalboni et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

COMT-Val158Met-Polymorphism Is Not a Risk Factor for Acute Kidney Injury after Cardiac Surgery

(2013) Matthias Kornek et al.   DISEASE MARKERS

Bardet–Biedl syndrome proteins control the cilia length through regulation of actin polymerization

(2013) Victor Hernandez-Hernandez et al.   HUMAN MOLECULAR GENETICS

Polymorphisms in the SUFU gene are associated with organ injury protection and sepsis severity in patients with Enterobacteriacea Bacteremia

(2013) Andrés F. Henao-Martínez et al.   INFECTION GENETICS AND EVOLUTION

Genetic predisposition to acute kidney injury induced by severe sepsis

(2013) Pablo Cardinal-Fernández et al.   JOURNAL OF CRITICAL CARE

Genetic deficiency of adiponectin protects against acute kidney injury

(2013) Xiaogao Jin et al.   KIDNEY INTERNATIONAL

Gender-specific association of NFKBIA promoter polymorphisms with the risk of sporadic colorectal cancer

(2013) Shing Cheng Tan et al.   MEDICAL ONCOLOGY

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Tumor Necrosis Factor Alpha Promoter Polymorphism and Severity of Acute Kidney Injury

(2013) Paweena Susantitaphong et al.   NEPHRON CLINICAL PRACTICE

Association of Functional Kallikrein-1 Promoter Polymorphisms and Acute Kidney Injury: A Case-Control and Longitudinal Cohort Study

(2013) Paweena Susantitaphong et al.   NEPHRON CLINICAL PRACTICE

APOL1 Risk Variants, Race, and Progression of Chronic Kidney Disease

(2013) Afshin Parsa et al.   NEW ENGLAND JOURNAL OF MEDICINE

The advantages and limitations of trait analysis with GWAS: a review

(2013) Arthur Korte et al.   Plant Methods

Significance and Suppression of Redundant IL17 Responses in Acute Allograft Rejection by Bioinformatics Based Drug Repositioning of Fenofibrate

(2013) Silke Roedder et al.   PLoS One

Apolipoprotein E genotype, TNF-α 308G/A and risk for cardiac surgery associated-acute kidney injury in Caucasians

(2013) Johannes Boehm et al.   RENAL FAILURE

MicroRNA-21 in the pathogenesis of acute kidney injury

(2013) Ya-Feng Li et al.   Protein & Cell

Acute Kidney Injury and Mortality in Hospitalized Patients

(2012) Henry E. Wang et al.   AMERICAN JOURNAL OF NEPHROLOGY

BCL2 genetic variants are associated with acute kidney injury in septic shock*

(2012) Angela J. Frank et al.   CRITICAL CARE MEDICINE

Cytokine phenotype, genotype, and renal outcomes at cardiac surgery

(2012) William T. McBride et al.   CYTOKINE

Gene polymorphisms and cytokine plasma levels as predictive factors of complications after cardiopulmonary bypass

(2012) Jérôme Jouan et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Polymorphisms in the myeloperoxidase gene locus are associated with acute kidney injury–related outcomes

(2012) Mary C. Perianayagam et al.   KIDNEY INTERNATIONAL

Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans

(2012) Michael S. Lipkowitz et al.   KIDNEY INTERNATIONAL

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

A Multicentre Study of Acute Kidney Injury in Severe Sepsis and Septic Shock: Association with Inflammatory Phenotype and HLA Genotype

(2012) Didier Payen et al.   PLoS One

Association of the IL-10 Gene Family Locus on Chromosome 1 with Juvenile Idiopathic Arthritis (JIA)

(2012) Ebun Omoyinmi et al.   PLoS One

US Renal Data System 2011 Annual Data Report

(2011) Allan J. Collins et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

RIFLE-Based Data Collection/Management System Applied to a Prospective Cohort Multicenter Italian Study on the Epidemiology of Acute Kidney Injury in the Intensive Care Unit

(2011) Francesco Garzotto et al.   BLOOD PURIFICATION

Curcumin immune-mediated and anti-apoptotic mechanisms protect against renal ischemia/reperfusion and distant organ induced injuries

(2011) Azza S. Awad et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cellular pathophysiology of ischemic acute kidney injury

(2011) Joseph V. Bonventre et al.   JOURNAL OF CLINICAL INVESTIGATION

Apoptosis and acute kidney injury

(2011) Andrea Havasi et al.   KIDNEY INTERNATIONAL

A study of the impact of cytokine gene polymorphism in acute rejection of renal transplant recipients

(2011) Mohammad Hossein Karimi et al.   MOLECULAR BIOLOGY REPORTS

Pathophysiology of ischemic acute kidney injury

(2011) Asif A. Sharfuddin et al.   Nature Reviews Nephrology

The Relationship Between Interferon-γ Gene Polymorphism and Acute Kidney Allograft Rejection

(2011) L. Zibar et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Kallistatin attenuates endothelial apoptosis through inhibition of oxidative stress and activation of Akt-eNOS signaling

(2010) Bo Shen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Relation Between Renal Dysfunction Requiring Renal Replacement Therapy and Promoter Polymorphism of the Erythropoietin Gene in Cardiac Surgery

(2010) Aron F. Popov et al.   ARTIFICIAL ORGANS

Targeting of renal proximal tubule Na,K-ATPase by salt-inducible kinase

(2010) Mary Taub et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vascular endothelial growth factors and vascular permeability

(2010) D. O. Bates   CARDIOVASCULAR RESEARCH

Urinary glutathione S-transferases in the pathogenesis and diagnostic evaluation of acute kidney injury following cardiac surgery: a critical review

(2010) Blaithin A McMahon et al.   Current Opinion in Critical Care

Kallistatin Inhibits Vascular Inflammation by Antagonizing Tumor Necrosis Factor-α–Induced Nuclear Factor κB Activation

(2010) Hang Yin et al.   HYPERTENSION

Adiponectin is produced by lymphocytes and is a negative regulator of granulopoiesis

(2010) Lisa J. A. Crawford et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mediators of Inflammation in Acute Kidney Injury

(2010) Ali Akcay et al.   MEDIATORS OF INFLAMMATION

Genome-wide association studies in diverse populations

(2010) Noah A. Rosenberg et al.   NATURE REVIEWS GENETICS

Phenylethanolamine N-Methyltransferase Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury

(2010) Ahsan Alam et al.   NEPHRON CLINICAL PRACTICE

Environment and Disease Risks

(2010) S. M. Rappaport et al.   SCIENCE

Replication in Genome-Wide Association Studies

(2010) Peter Kraft et al.   STATISTICAL SCIENCE

Searching for Genes That Matter in Acute Kidney Injury: A Systematic Review

(2009) J. C. T. Lu et al.   Clinical Journal of the American Society of Nephrology

The eNOS 786C/T polymorphism in cardiac surgical patients with cardiopulmonary bypass is associated with renal dysfunction

(2009) Aron Frederik Popov et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Evaluation of “Loss” and “End stage renal disease” after acute kidney injury defined by the Risk, Injury, Failure, Loss and ESRD classification in critically ill patients

(2009) Rodrigo Cartin-Ceba et al.   INTENSIVE CARE MEDICINE

Decreased Catecholamine Degradation Associates with Shock and Kidney Injury after Cardiac Surgery

(2009) A. Haase-Fielitz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Acute Kidney Injury Associates with Increased Long-Term Mortality

(2009) J.-P. Lafrance et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A genetic variant of hypoxia-inducible factor-1α is associated with adverse outcomes in acute kidney injury

(2009) Alexey Y. Kolyada et al.   KIDNEY INTERNATIONAL

Angiotensin converting enzyme insertion/deletion genetic polymorphism: Its impact on renal function in critically ill patients*

(2008) Damien du Cheyron et al.   CRITICAL CARE MEDICINE

IL-6/IL-6R Axis Plays a Critical Role in Acute Kidney Injury

(2008) Y. Nechemia-Arbely et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Serum adiponectin predicts all-cause mortality and end stage renal disease in patients with type I diabetes and diabetic nephropathy

(2008) Anders Jorsal et al.   KIDNEY INTERNATIONAL

Association of anemia and erythropoiesis stimulating agents with inflammatory biomarkers in chronic kidney disease

(2008) Sai Ram Keithi-Reddy et al.   KIDNEY INTERNATIONAL

Inflammation in Acute Kidney Injury

(2008) Gilbert R. Kinsey et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Common interleukin-6 promoter variants associate with the more severe forms of distal interphalangeal osteoarthritis

(2008) Olli-Pekka Kämäräinen et al.   ARTHRITIS RESEARCH & THERAPY