Current research status of HLA in immune‐related diseases

Genotyping of immune-related loci associated with delayed HBeAg seroconversion in immune-active chronic hepatitis B patients

(2020) Wen-Chun Liu et al.   ANTIVIRAL RESEARCH

Clinical and genetic markers associated with tuberculosis, HIV-1 infection, and TB/HIV-immune reconstitution inflammatory syndrome outcomes

(2020) Nathalia Beatriz Ramos de Sá et al.   BMC INFECTIOUS DISEASES

Peripheral innate immune and bacterial signals relate to clinical heterogeneity in Parkinson’s disease

(2020) Ruwani S. Wijeyekoon et al.   BRAIN BEHAVIOR AND IMMUNITY

Curcumin stimulates angiogenesis through VEGF and expression of HLA‐G in first‐trimester human placental trophoblasts

(2020) Sanjay Basak et al.   CELL BIOLOGY INTERNATIONAL

MHC Class II (DRB) Promoter Polymorphism and Its Role in Parasite Control among Malaria Patients

(2020) Pranati Sar et al.   JOURNAL OF IMMUNOLOGY

Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia

(2020) Dimitri Poddighe et al.   PLoS One

Upregulation of HLA Class I and Antiviral Tissue Responses in Hashimoto's Thyroiditis

(2020) Therese Weider et al.   THYROID

Decreased Soluble Human Leukocyte Antigen E Levels in Patients After Allogeneic Hematopoietic Stem Cell Transplantation Are Associated With Severe Acute and Extended Chronic Graft-versus-Host Disease and Inferior Overall Survival

(2020) Lambros Kordelas et al.   Frontiers in Immunology

Detection of 6pLOH in an aplastic anemia patient by in phase HLA genotyping

(2020) Eri Kikkawa et al.   HLA

Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis

(2020) Takashi Maehara et al.   JOURNAL OF CLINICAL INVESTIGATION

KIR/HLA Gene Profile Implication in Systemic Sclerosis Patients from Mexico

(2019) Andrea Carolina Machado-Sulbaran et al.   Journal of Immunology Research

Coeliac disease

(2019) Katri Lindfors et al.   Nature Reviews Disease Primers

Escape hematopoiesis by HLA-B5401-lacking hematopoietic stem progenitor cells in men with acquired aplastic anemia

(2019) Mahmoud I. Elbadry et al.   HAEMATOLOGICA

Relevance of HLA-DQB1*02 Allele in the Genetic Predisposition of Children with Celiac Disease: Additional Cues from a Meta-Analysis

(2019) Cristina Capittini et al.   Medicina-Lithuania

HLA associations in inflammatory arthritis: emerging mechanisms and clinical implications

(2019) Robert Busch et al.   Nature Reviews Rheumatology

The influence of HLA-B51 on clinical manifestations among Japanese patients with Behçet’s disease: A nationwide survey

(2019) Yuki Mizuki et al.   Modern Rheumatology

Association of Functional Polymorphisms of KIR3DL1/DS1 With Behçet's Disease

(2019) Ángel Castaño-Núñez et al.   Frontiers in Immunology

Epstein–Barr virus-positive diffuse large B-cell lymphoma features disrupted antigen capture/presentation and hijacked T-cell suppression

(2019) Xiang-Nan Jiang et al.   OncoImmunology

IgG4-related disease: How to place it in the spectrum of immune-mediated and rheumatologic disorders?

(2019) Tiago Borges et al.   Modern Rheumatology

Entropy of human leukocyte antigen and killer-cell immunoglobulin-like receptor systems in immune-mediated disorders: A pilot study on multiple sclerosis

(2019) Maurizio Melis et al.   PLoS One

Foetal and neonatal alloimmune thrombocytopenia – The role of the HLA-DRB3*01:01 allele for HPA-1a-immunisation and foetal/neonatal outcome

(2019) Jens Kjeldsen-Kragh et al.   TRANSFUSION AND APHERESIS SCIENCE

AAV-mediated expression of HLA-G1/5 reduces severity of experimental autoimmune uveitis

(2019) Elizabeth Crabtree et al.   Scientific Reports

Exome Sequencing Identifies Susceptibility Loci for Sarcoidosis Prognosis

(2019) Elisa Lahtela et al.   Frontiers in Immunology

HHV-6A Infection and Systemic Sclerosis: Clues of a Possible Association

(2019) Elisabetta Caselli et al.   Microorganisms

CD4+ T cell-mediated rejection of MHC class II-positive tumor cells is dependent on antigen secretion and indirect presentation on host APCs

(2018) Ole Audun Werner Haabeth et al.   CANCER RESEARCH

HLA-DQB1*03:01 as a Biomarker for Genetic Susceptibility to Bullous Pemphigoid Induced by DPP-4 Inhibitors

(2018) Hideyuki Ujiie et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The HLA-DQB1*03:01 Is Associated with Bullous Pemphigoid in the Han Chinese Population

(2018) Yonghu Sun et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

HLA-DQ genetics in children with celiac disease: a meta-analysis suggesting a two-step genetic screening procedure starting with HLA-DQ β chains

(2018) Annalisa De Silvestri et al.   PEDIATRIC RESEARCH

Association between KIR-HLA combination and ulcerative colitis and Crohn’s disease in a Japanese population

(2018) Hiromi Saito et al.   PLoS One

Association betweenhuman leucocyte antigen-DOpolymorphisms and interferon/ribavirin treatment response in hepatitis C virus type 1 infection in Chinese population: a prospective study

(2018) Yinan Yao et al.   BMJ Open

Peptide presentation by HLA-DQ molecules is associated with the development of immune tolerance

(2018) Máté Manczinger et al.   PeerJ

The role of HLA-G in parasitic diseases

(2018) A. Sabbagh et al.   HLA

Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson’s disease

(2018) Gregory P. Williams et al.   Journal of Neuroinflammation

Autologous Dendritic Cell Therapy in Mesothelioma Patients Enhances Frequencies of Peripheral CD4 T Cells Expressing HLA-DR, PD-1, or ICOS

(2018) Pauline L. de Goeje et al.   Frontiers in Immunology

Maternal HPA-1a antibody level and its role in predicting the severity of Fetal/Neonatal Alloimmune Thrombocytopenia: a systematic review

(2018) Mette Kjaer et al.   VOX SANGUINIS

Role of HLA-DP and HLA-DQ on the clearance of hepatitis B virus and the risk of chronic infection in a multiethnic population

(2017) Julieta Trinks et al.   LIVER INTERNATIONAL

Identifying specificity groups in the T cell receptor repertoire

(2017) Jacob Glanville et al.   NATURE

Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet's disease susceptibility

(2017) Masaki Takeuchi et al.   NATURE GENETICS

Human Leukocyte Antigen–Disease Associations in Rheumatoid Arthritis

(2017) Vincent van Drongelen et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants

(2017) Jason H. Karnes et al.   Science Translational Medicine

HLA Epitopes: The Targets of Monoclonal and Alloantibodies Defined

(2017) Nadim El-Awar et al.   Journal of Immunology Research

AAV vector-meditated expression of HLA-G reduces injury-induced corneal vascularization, immune cell infiltration, and fibrosis

(2017) Matthew L. Hirsch et al.   Scientific Reports

Systemic-onset juvenile idiopathic arthritis

(2016) Rolando Cimaz   AUTOIMMUNITY REVIEWS

Maternal HLA genotyping is not useful for predicting severity of fetal and neonatal alloimmune thrombocytopenia

(2016) Susanna Sainio et al.   BRITISH JOURNAL OF HAEMATOLOGY

Clinical significance and origin of leukocytes that lack HLA-A allele expression in patients with acquired aplastic anemia

(2016) Hiroyuki Maruyama et al.   EXPERIMENTAL HEMATOLOGY

HLA-B51 Carriers are Susceptible to Ocular Symptoms of Behçet Disease and the Association between the Two Becomes Stronger towards the East along the Silk Road: A Literature Survey

(2016) Yukihiro Horie et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

HLA-DRB3*01:01 is a predictor of immunization against human platelet antigen-1a but not of the severity of fetal and neonatal alloimmune thrombocytopenia

(2016) Sandra Wienzek-Lischka et al.   TRANSFUSION

A Comparative Analysis of the Peptide Repertoires of HLA-DR Molecules Differentially Associated With Rheumatoid Arthritis

(2016) Erika Scholz et al.   Arthritis & Rheumatology

Clinical Relevance of HLA Gene Variants in HBV Infection

(2016) Li Wang et al.   Journal of Immunology Research

Human Leukocyte Antigen and Systemic Sclerosis in Japanese: The Sign of the Four Independent Protective Alleles, DRB1*13:02, DRB1*14:06, DQB1*03:01, and DPB1*02:01

(2016) Hiroshi Furukawa et al.   PLoS One

Inhibitory KIR3DL1 alleles are associated with psoriasis

(2015) R.S. Ahn et al.   BRITISH JOURNAL OF DERMATOLOGY

Induction of HLA-B*40:02-restricted T cells possessing cytotoxic and suppressive functions against haematopoietic progenitor cells from a patient with severe aplastic anaemia

(2015) Yoko Inaguma et al.   BRITISH JOURNAL OF HAEMATOLOGY

Increased prevalence ofMEFVexon 10 variants in Japanese patients with adult-onset Still's disease

(2015) F. Nonaka et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Clinical correlates of human leucocyte antigen (HLA)-G in systemic sclerosis1

(2015) E. Favoino et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Pemphigus is associated withKIR3DL2expression levels and provides evidence that KIR3DL2 may bind HLA-A3 and A11 in vivo

(2015) Danillo G. Augusto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human leukocyte antigen polymorphisms and personalized medicine for rheumatoid arthritis

(2015) Hiroshi Furukawa et al.   JOURNAL OF HUMAN GENETICS

HLA-DRB1*11and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis

(2015) Michael J. Ombrello et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fetal and neonatal alloimmune thrombocytopenia: predictive factors of intracranial hemorrhage

(2015) Florent Delbos et al.   TRANSFUSION

Interactions Between Amino Acid-Defined Major Histocompatibility Complex Class II Variants and Smoking in Seropositive Rheumatoid Arthritis

(2015) Kwangwoo Kim et al.   Arthritis & Rheumatology

Behçet’s Disease: Do Natural Killer Cells Play a Significant Role?

(2015) Harry Petrushkin et al.   Frontiers in Immunology

Coexisting primary Sjögren’s syndrome and sarcoidosis: coincidence, mutually exclusive conditions or syndrome?

(2014) T. Santiago et al.   RHEUMATOLOGY INTERNATIONAL

Interactions between HLA-G and HLA-E in Physiological and Pathological Conditions

(2014) Fabio Morandi et al.   Frontiers in Immunology

Major Histocompatibility Complex Genomics and Human Disease

(2013) John Trowsdale et al.   Annual Review of Genomics and Human Genetics

Posttranslational Modification of HLA-DQ Binding Islet Autoantigens in Type 1 Diabetes

(2013) M. van Lummel et al.   DIABETES

An HLA-DRB1-Coded Signal Transduction Ligand Facilitates Inflammatory Arthritis: A New Mechanism of Autoimmunity

(2012) J. Holoshitz et al.   JOURNAL OF IMMUNOLOGY

DQB1*0602 rather than DRB1*1501 confers susceptibility to multiple sclerosis-like disease induced by proteolipid protein (PLP)

(2012) Nathali Kaushansky et al.   Journal of Neuroinflammation

Developing potent backbone cyclic peptides bearing the shared epitope sequence as rheumatoid arthritis drug-leads

(2011) Shirly Naveh et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Frequent loss of HLA alleles associated with copy number-neutral 6pLOH in acquired aplastic anemia

(2011) T. Katagiri et al.   BLOOD

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: A meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein

(2010) Diane van der Woude et al.   ARTHRITIS AND RHEUMATISM

Recent progress in rheumatoid arthritis genetics: one step towards improved patient care

(2010) Robert M Plenge   CURRENT OPINION IN RHEUMATOLOGY

Association between Protective and Deleterious HLA Alleles with Multiple Sclerosis in Central East Sardinia

(2009) Roberta Pastorino et al.   PLoS One