Dominant Bacterial Phyla from the Human Gut Show Widespread Ability To Transform and Conjugate Bile Acids

Global chemical effects of the microbiome include new bile-acid conjugations

(2020) Robert A. Quinn et al.   NATURE

A metabolic pathway for bile acid dehydroxylation by the gut microbiome

(2020) Masanori Funabashi et al.   NATURE

Gut-derived Flavonifractor species variants are differentially enriched during in vitro incubation with quercetin

(2020) Gina Paola Rodriguez-Castaño et al.   PLoS One

Systematic assessment of secondary bile acid metabolism in gut microbes reveals distinct metabolic capabilities in inflammatory bowel disease

(2019) Almut Heinken et al.   Microbiome

Structural and biochemical characterization of 20β-hydroxysteroid dehydrogenase from Bifidobacterium adolescentis strain L2-32

(2019) Heidi L. Doden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Comprehensive Genome Survey Provides Novel Insights into Bile Salt Hydrolase (BSH) in Lactobacillaceae

(2018) Lifeng Liang et al.   MOLECULES

Metabolism of Oxo-Bile Acids and Characterization of Recombinant 12α-Hydroxysteroid Dehydrogenases from Bile Acid 7α-Dehydroxylating Human Gut Bacteria

(2018) Heidi Doden et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Gut microbiota functions: metabolism of nutrients and other food components

(2017) Ian Rowland et al.   EUROPEAN JOURNAL OF NUTRITION

Bile acids and colon cancer: Is FXR the solution of the conundrum?

(2017) Raffaella Maria Gadaleta et al.   MOLECULAR ASPECTS OF MEDICINE

Rapid analysis of bile acids in different biological matrices using LC-ESI-MS/MS for the investigation of bile acid transformation by mammalian gut bacteria

(2016) Katrin Wegner et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Interaction of gut microbiota with bile acid metabolism and its influence on disease states

(2016) Christopher Staley et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Liver Cancer Checks in When Bile Acid Clocks Out

(2016) Ting Fu et al.   CANCER CELL

The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics

(2015) Jason M. Ridlon et al.   Acta Pharmaceutica Sinica B

Bile acids and the gut microbiome

(2014) Jason M. Ridlon et al.   CURRENT OPINION IN GASTROENTEROLOGY

The bile acid TGR5 membrane receptor: From basic research to clinical application

(2014) Henri Duboc et al.   DIGESTIVE AND LIVER DISEASE

Key discoveries in bile acid chemistry and biology and their clinical applications: history of the last eight decades

(2014) Alan F. Hofmann et al.   JOURNAL OF LIPID RESEARCH

Bile acids are nutrient signaling hormones

(2014) Huiping Zhou et al.   STEROIDS

Microbiota transplantation restores normal fecal bile acid composition in recurrent Clostridium difficile infection

(2013) Alexa R. Weingarden et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Pleiotropic Roles of Bile Acids in Metabolism

(2013) Thomas Q. de Aguiar Vallim et al.   Cell Metabolism

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

Genetic Diversity of Bile Salt Hydrolases Among Human Intestinal Bifidobacteria

(2013) Piotr Jarocki et al.   CURRENT MICROBIOLOGY

Contribution of the 7β-hydroxysteroid dehydrogenase fromRuminococcus gnavusN53 to ursodeoxycholic acid formation in the human colon

(2013) Ja-Young Lee et al.   JOURNAL OF LIPID RESEARCH

Hydroxysteroid dehydrogenases (HSDs) in bacteria – A bioinformatic perspective

(2011) Michael Kisiela et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Accelerated Profile HMM Searches

(2011) Sean R. Eddy   PLoS Computational Biology

Metabolomic Analysis and Visualization Engine for LC−MS Data

(2010) Eugene Melamud et al.   ANALYTICAL CHEMISTRY

Identification, cloning, heterologous expression, and characterization of a NADPH-dependent 7β-hydroxysteroid dehydrogenase from Collinsella aerofaciens

(2010) Luo Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Isolation and characterization of a bile acid inducible 7α-dehydroxylating operon in Clostridium hylemonae TN271

(2009) Jason M. Ridlon et al.   ANAEROBE

Conversion of cholic acid and chenodeoxycholic acid into their 7-oxo derivatives byBacteroides intestinalisAM-1 isolated from human feces

(2009) Satoru Fukiya et al.   FEMS MICROBIOLOGY LETTERS

The metagenomics RAST server – a public resource for the automatic phylogenetic and functional analysis of metagenomes

(2008) F Meyer et al.   BMC BIOINFORMATICS

Bile Acids: Chemistry, Pathochemistry, Biology, Pathobiology, and Therapeutics

(2008) A. F. Hofmann et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome

(2008) B. V. Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA