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(2021) Ignacio Melero et al.   Nature Reviews Clinical Oncology

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Neutrophilic granule protein (NGP) attenuates lipopolysaccharide-induced inflammatory responses and enhances phagocytosis of bacteria by macrophages

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Innate Immune Defense Mechanisms by Myeloid Cells That Hamper Cancer Immunotherapy

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S100A8 and S100A9 Promote Apoptosis of Chronic Eosinophilic Leukemia Cells

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M1hot tumor-associated macrophages boost tissue-resident memory T cells infiltration and survival in human lung cancer

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Intratumoral nanoplexed poly I:C BO-112 in combination with systemic anti–PD-1 for patients with anti–PD-1–refractory tumors

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Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma

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Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response

(2019) Camilla Salvagno et al.   NATURE CELL BIOLOGY

Antigen delivery targeted to tumor-associated macrophages overcomes tumor immune resistance

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Poly(I:C) stimulation is superior than Imiquimod to induce the antitumoral functional profile of tumor-conditioned macrophages

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Immunotherapeutic effects of intratumoral nanoplexed poly I:C

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Human GBP1 is a microbe‐specific gatekeeper of macrophage apoptosis and pyroptosis

(2019) Daniel Fisch et al.   EMBO JOURNAL

Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment

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Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies

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Shmt2: A Stat3 Signaling New Player in Prostate Cancer Energy Metabolism

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Proteomic analysis of extracellular vesicles derived from platelet concentrates treated with Mirasol® identifies biomarkers of platelet storage lesion

(2019) Lidia Hermida-Nogueira et al.   Journal of Proteomics

Current Strategies to Target Tumor-Associated-Macrophages to Improve Anti-Tumor Immune Responses

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Combined immunotherapy encompassing intratumoral poly-ICLC, dendritic-cell vaccination and radiotherapy in advanced cancer patients

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TLR-mediated metabolic reprogramming in the tumor microenvironment: potential novel strategies for cancer immunotherapy

(2018) Lan Huang et al.   Cellular & Molecular Immunology

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

(2018) Christopher B. Rodell et al.   Nature Biomedical Engineering

Cytoscape StringApp: Network Analysis and Visualization of Proteomics Data

(2018) Nadezhda T. Doncheva et al.   JOURNAL OF PROTEOME RESEARCH

Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma

(2018) Michaël Cerezo et al.   NATURE MEDICINE

Targeting macrophages: therapeutic approaches in cancer

(2018) Luca Cassetta et al.   NATURE REVIEWS DRUG DISCOVERY

Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy

(2018) Yangbo Feng et al.   Cancer Medicine

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Systematic Investigation of Multi-TLR Sensing Identifies Regulators of Sustained Gene Activation in Macrophages

(2017) Bin Lin et al.   Cell Systems

Innate immune memory and homeostasis may be conferred through crosstalk between the TLR3 and TLR7 pathways

(2016) Bing Liu et al.   Science Signaling

Innate immune memory and homeostasis may be conferred through crosstalk between the TLR3 and TLR7 pathways

(2016) Bing Liu et al.   Science Signaling

TLR7-based cancer immunotherapy decreases intratumoral myeloid-derived suppressor cells and blocks their immunosuppressive function

(2016) Thibaud Spinetti et al.   OncoImmunology

Cystatin B as a potential diagnostic biomarker in ovarian clear cell carcinoma

(2015) AKANE TAKAYA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Regulation of TLR3 Activation by S100A9

(2015) Su-Yu Tsai et al.   JOURNAL OF IMMUNOLOGY

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Orosomucoid 2 inhibits tumor metastasis and is upregulated by CCAAT/enhancer binding protein β in hepatocellular carcinomas

(2015) Tao Fang et al.   Oncotarget

TLR7 Promotes Tumor Progression, Chemotherapy Resistance, and Poor Clinical Outcomes in Non-Small Cell Lung Cancer

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Therapy with TLR7 Agonists Induces Lymphopenia: Correlating Pharmacology to Mechanism in a Mouse Model

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