Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations
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Title
Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations
Authors
Keywords
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Journal
Journal for ImmunoTherapy of Cancer
Volume 9, Issue 7, Pages e002531
Publisher
BMJ
Online
2021-07-08
DOI
10.1136/jitc-2021-002531
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Note: Only part of the references are listed.- Exploiting Tumor Neoantigens to Target Cancer Evolution: Current Challenges and Promising Therapeutic Approaches
- (2021) Ravi G. Gupta et al. Cancer Discovery
- The Roles of Initiating Truncal Mutations in Human Cancers: The Order of Mutations and Tumor Cell Type Matters
- (2019) Arnold J. Levine et al. CANCER CELL
- Identification of Novel HLA Class II-Restricted Neoantigens Derived from Driver Mutations
- (2019) Susumu Iiizumi et al. Cancers
- Retrospective efficacy analysis of immune checkpoint inhibitors in patients with EGFR-mutated non-small cell lung cancer
- (2019) Tadaaki Yamada et al. Cancer Medicine
- Neoantigen-directed immune escape in lung cancer evolution
- (2019) Rachel Rosenthal et al. NATURE
- Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers
- (2019) Parisa Malekzadeh et al. JOURNAL OF CLINICAL INVESTIGATION
- Neoantigen identification strategies enable personalized immunotherapy in refractory solid tumors
- (2019) Fangjun Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop
- (2019) Davide Bedognetti et al. Journal for ImmunoTherapy of Cancer
- EGFR mutation subtypes and response to immune checkpoint blockade treatment in non-small-cell lung cancer
- (2019) K Hastings et al. ANNALS OF ONCOLOGY
- Improved methods for predicting peptide binding affinity to MHC class II molecules
- (2018) Kamilla Kjaergaard Jensen et al. IMMUNOLOGY
- Perturbation-response genes reveal signaling footprints in cancer gene expression
- (2018) Michael Schubert et al. Nature Communications
- The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer
- (2018) Najwa El Kadi et al. CANCER RESEARCH
- Mutational activation of the epidermal growth factor receptor down-regulates major histocompatibility complex class I expression via the extracellular signal-regulated kinase in non-small cell lung cancer
- (2018) Satomi Watanabe et al. CANCER SCIENCE
- Actively personalized vaccination trial for newly diagnosed glioblastoma
- (2018) Norbert Hilf et al. NATURE
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
- (2018) Derin B. Keskin et al. NATURE
- Mechanism of Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors and a Potential Treatment Strategy
- (2018) Tatsuya Nagano et al. Cells
- Molecular-Targeted Therapies for Epidermal Growth Factor Receptor and Its Resistance Mechanisms
- (2017) Toshimitsu Yamaoka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
- (2017) Ugur Sahin et al. NATURE
- An immunogenic personal neoantigen vaccine for patients with melanoma
- (2017) Patrick A. Ott et al. NATURE
- Targeting the PD-1/PD-L1 Immune Checkpoint in EGFR-Mutated or ALK-Translocated Non-Small-Cell Lung Cancer
- (2017) Olivier Bylicki et al. Targeted Oncology
- Mechanisms of resistance to irreversible epidermal growth factor receptor tyrosine kinase inhibitors and therapeutic strategies in non-small cell lung cancer
- (2017) Jing Xu et al. Oncotarget
- Neoantigen Targeting—Dawn of a New Era in Cancer Immunotherapy?
- (2017) Thomas C. Wirth et al. Frontiers in Immunology
- Not all epidermal growth factor receptor mutations in lung cancer are created equal: Perspectives for individualized treatment strategy
- (2016) Yoshihisa Kobayashi et al. CANCER SCIENCE
- A Novel Method to Detect Functional microRNA Regulatory Modules by Bicliques Merging
- (2016) Cheng Liang et al. IEEE-ACM Transactions on Computational Biology and Bioinformatics
- Near-optimal probabilistic RNA-seq quantification
- (2016) Nicolas L Bray et al. NATURE BIOTECHNOLOGY
- Spatial intratumoral heterogeneity and temporal clonal evolution in esophageal squamous cell carcinoma
- (2016) Jia-Jie Hao et al. NATURE GENETICS
- Cancer immunotherapy targeting neoantigens
- (2016) Yong-Chen Lu et al. SEMINARS IN IMMUNOLOGY
- EGFR-targeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models
- (2016) Abhilash Venugopalan et al. Oncotarget
- Rapid tumor regression in an Asian lung cancer patient following personalized neo-epitope peptide vaccination
- (2016) Fenge Li et al. OncoImmunology
- Immune-Modulation by Epidermal Growth Factor Receptor Inhibitors: Implication on Anti-Tumor Immunity in Lung Cancer
- (2016) Jin S. Im et al. PLoS One
- EGFR-TKI down-regulates PD-L1 in EGFR mutant NSCLC through inhibiting NF-κB
- (2015) Kailong Lin et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Gapped sequence alignment using artificial neural networks: application to the MHC class I system
- (2015) Massimo Andreatta et al. BIOINFORMATICS
- Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR Mutation
- (2015) Nan Chen et al. Journal of Thoracic Oncology
- Mutant MHC class II epitopes drive therapeutic immune responses to cancer
- (2015) Sebastian Kreiter et al. NATURE
- Human CD4+ T cells spontaneously detect somatic mutations in cancer cells
- (2015) Willem W Overwijk NATURE MEDICINE
- A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells
- (2015) B. M. Carreno et al. SCIENCE
- Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
- (2015) N. A. Rizvi et al. SCIENCE
- Trial Watch: Peptide-based anticancer vaccines
- (2015) Jonathan Pol et al. OncoImmunology
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
- Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations
- (2014) Faviel F. González-Galarza et al. NUCLEIC ACIDS RESEARCH
- Clustering HLA Class I Superfamilies Using Structural Interaction Patterns
- (2014) Sumitro Harjanto et al. PLoS One
- Cancer Immunotherapy Based on Mutation-Specific CD4+ T Cells in a Patient with Epithelial Cancer
- (2014) E. Tran et al. SCIENCE
- HLA-F and MHC-I Open Conformers Cooperate in a MHC-I Antigen Cross-Presentation Pathway
- (2013) J. P. Goodridge et al. JOURNAL OF IMMUNOLOGY
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion
- (2013) Yared Hailemichael et al. NATURE MEDICINE
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- HLA class I supertypes: a revised and updated classification
- (2008) John Sidney et al. BMC IMMUNOLOGY
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