Prdm16-mediated H3K9 methylation controls fibro-adipogenic progenitors identity during skeletal muscle repair

Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA Lnc-Rewind in muscle stem cells

(2021) Andrea Cipriano et al.   eLife

Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice

(2020) Darko Bosnakovski et al.   JOURNAL OF CLINICAL INVESTIGATION

H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification

(2019) Dario Nicetto et al.   SCIENCE

Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors

(2019) Laura Lukjanenko et al.   Cell Stem Cell

Promoter-Intrinsic and Local Chromatin Features Determine Gene Repression in LADs

(2019) Christ Leemans et al.   CELL

Mesenchymal Stromal Cells Are Required for Regeneration and Homeostatic Maintenance of Skeletal Muscle

(2019) Michael N. Wosczyna et al.   Cell Reports

Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B

(2019) Marshall W. Hogarth et al.   Nature Communications

Modulating Cell Fate as a Therapeutic Strategy

(2018) Brian Lin et al.   Cell Stem Cell

Shaping Gene Expression by Landscaping Chromatin Architecture: Lessons from a Master

(2018) Vittorio Sartorelli et al.   MOLECULAR CELL

Denervation-activated STAT3–IL-6 signalling in fibro-adipogenic progenitors promotes myofibres atrophy and fibrosis

(2018) Luca Madaro et al.   NATURE CELL BIOLOGY

Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva

(2018) John B. Lees-Shepard et al.   Nature Communications

Deficiency in the nuclear long noncoding RNA Charme causes myogenic defects and heart remodeling in mice

(2018) Monica Ballarino et al.   EMBO JOURNAL

Odd skipped-related 1 (Osr1) identifies muscle-interstitial fibro-adipogenic progenitors (FAPs) activated by acute injury

(2018) Jürgen Stumm et al.   Stem Cell Research

Heavy-tailed prior distributions for sequence count data: removing the noise and preserving large differences

(2018) Anqi Zhu et al.   BIOINFORMATICS

Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris

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Coaching from the sidelines: the nuclear periphery in genome regulation

(2018) Abigail Buchwalter et al.   NATURE REVIEWS GENETICS

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(2018) Adam Frankish et al.   NUCLEIC ACIDS RESEARCH

A Twist2-dependent progenitor cell contributes to adult skeletal muscle

(2017) Ning Liu et al.   NATURE CELL BIOLOGY

Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development

(2017) Pedro Vallecillo-García et al.   Nature Communications

LSD1 Controls Timely MyoD Expression via MyoD Core Enhancer Transcription

(2017) Isabella Scionti et al.   Cell Reports

Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis

(2016) Osvaldo Contreras et al.   CELL AND TISSUE RESEARCH

Intravital Imaging Reveals Ghost Fibers as Architectural Units Guiding Myogenic Progenitors during Regeneration

(2016) Micah T. Webster et al.   Cell Stem Cell

Regulation of Skeletal Muscle Stem Cell Quiescence by Suv4-20h1-Dependent Facultative Heterochromatin Formation

(2016) Verawan Boonsanay et al.   Cell Stem Cell

Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis

(2016) Michael I. Robson et al.   MOLECULAR CELL

Data-driven hypothesis weighting increases detection power in genome-scale multiple testing

(2016) Nikolaos Ignatiadis et al.   NATURE METHODS

G9a promotes proliferation and inhibits cell cycle exit during myogenic differentiation

(2016) Vinay Kumar Rao et al.   NUCLEIC ACIDS RESEARCH

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

Pharmacological blockage of fibro/adipogenic progenitor expansion and suppression of regenerative fibrogenesis is associated with impaired skeletal muscle regeneration

(2016) Daniela Fiore et al.   Stem Cell Research

H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes

(2016) Justin S. Becker et al.   TRENDS IN GENETICS

The lysine methyltransferase Ehmt2/G9a is dispensable for skeletal muscle development and regeneration

(2016) Regan-Heng Zhang et al.   Skeletal Muscle

Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos

(2015) Adriana Gonzalez-Sandoval et al.   CELL

Barrier to Autointegration Factor (BANF1): interwoven roles in nuclear structure, genome integrity, innate immunity, stress responses and progeria

(2015) Augusta Jamin et al.   CURRENT OPINION IN CELL BIOLOGY

PRDM16 enhances nuclear receptor-dependent transcription of the brown fat-specificUcp1gene through interactions with Mediator subunit MED1

(2015) Satoshi Iida et al.   GENES & DEVELOPMENT

PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program

(2015) Matthew J. Harms et al.   GENES & DEVELOPMENT

A KAP1 phosphorylation switch controls MyoD function during skeletal muscle differentiation

(2015) Kulwant Singh et al.   GENES & DEVELOPMENT

Nilotinib reduces muscle fibrosis in chronic muscle injury by promoting TNF-mediated apoptosis of fibro/adipogenic progenitors

(2015) Dario R Lemos et al.   NATURE MEDICINE

Sound of silence: the properties and functions of repressive Lys methyltransferases

(2015) Chiara Mozzetta et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SAMBLASTER: fast duplicate marking and structural variant read extraction

(2014) G. G. Faust et al.   BIOINFORMATICS

Nonstochastic Reprogramming from a Privileged Somatic Cell State

(2014) Shangqin Guo et al.   CELL

Antagonism between the Master Regulators of Differentiation Ensures the Discreteness and Robustness of Cell Fates

(2014) Kazunori Sunadome et al.   MOLECULAR CELL

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Enriched domain detector: a program for detection of wide genomic enrichment domains robust against local variations

(2014) Eivind Lund et al.   NUCLEIC ACIDS RESEARCH

Discovery and Development of Potent and Selective Inhibitors of Histone Methyltransferase G9a

(2014) Ramzi F. Sweis et al.   ACS Medicinal Chemistry Letters

Quantitative ChIP-Seq Normalization Reveals Global Modulation of the Epigenome

(2014) David A. Orlando et al.   Cell Reports

Mitosis Gives a Brief Window of Opportunity for a Change in Gene Transcription

(2014) Richard P. Halley-Stott et al.   PLOS BIOLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Single-Cell Dynamics of Genome-Nuclear Lamina Interactions

(2013) Jop Kind et al.   CELL

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

(2013) Jose E. Heredia et al.   CELL

LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation

(2013) Irina Solovei et al.   CELL

Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

(2013) Chiara Mozzetta et al.   EMBO Molecular Medicine

Lamin A/C-promoter interactions specify chromatin state-dependent transcription outcomes

(2013) E. Lund et al.   GENOME RESEARCH

EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex

(2013) Haruya Ohno et al.   NATURE

High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states

(2013) Ronnie Blecher-Gonen et al.   Nature Protocols

Modulation of lysine methylation in myocyte enhancer factor 2 during skeletal muscle cell differentiation

(2013) Jinmi Choi et al.   NUCLEIC ACIDS RESEARCH

The Human Protein PRR14 Tethers Heterochromatin to the Nuclear Lamina during Interphase and Mitotic Exit

(2013) Andrey Poleshko et al.   Cell Reports

Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery

(2013) Nikolaj Zuleger et al.   GENOME BIOLOGY

The nuclear envelope LEM-domain protein emerin

(2013) Jason M Berk et al.   Nucleus

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity

(2012) Inês Pinheiro et al.   CELL

DNA Sequence-Dependent Compartmentalization and Silencing of Chromatin at the Nuclear Lamina

(2012) Joseph M. Zullo et al.   CELL

Step-Wise Methylation of Histone H3K9 Positions Heterochromatin at the Nuclear Periphery

(2012) Benjamin D. Towbin et al.   CELL

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Lysine methyltransferase G9a methylates the transcription factor MyoD and regulates skeletal muscle differentiation

(2012) B. M. T. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H3K9 methyltransferase G9a and the related molecule GLP

(2011) Y. Shinkai et al.   GENES & DEVELOPMENT

Subnuclear segregation of genes and core promoter factors in myogenesis

(2011) Jie Yao et al.   GENES & DEVELOPMENT

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle

(2011) A. Uezumi et al.   JOURNAL OF CELL SCIENCE

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

(2010) Daan Peric-Hupkes et al.   MOLECULAR CELL

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

(2010) Akiyoshi Uezumi et al.   NATURE CELL BIOLOGY

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

(2010) Aaron W. B. Joe et al.   NATURE CELL BIOLOGY

Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

(2009) Bo Wen et al.   NATURE GENETICS

G9a selectively represses a class of late-replicating genes at the nuclear periphery

(2009) T. Yokochi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

(2008) Lars Guelen et al.   NATURE

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE