Mycobacterium tuberculosis PE_PGRS20 and PE_PGRS47 Proteins Inhibit Autophagy by Interaction with Rab1A

Arginine GlcNAcylation of Rab small GTPases by the pathogen Salmonella Typhimurium

(2020) Kun Meng et al.   Communications Biology

Identification of autophagy inhibiting factors of Mycobacterium tuberculosis by high throughput loss of function screening

(2020) Emily J Strong et al.   INFECTION AND IMMUNITY

Rab1A promotes proliferation and migration abilities via regulation of the HER2/AKT-independent mTOR/S6K1 pathway in colorectal cancer

(2019) Zhengwu Cheng et al.   ONCOLOGY REPORTS

Group A Streptococcus modulates RAB1- and PIK3C3 complex-dependent autophagy

(2019) Hirotaka Toh et al.   Autophagy

The EMBL-EBI search and sequence analysis tools APIs in 2019

(2019) Fábio Madeira et al.   NUCLEIC ACIDS RESEARCH

Expression analysis and implication of Rab1A in gastrointestinal relevant tumor

(2019) Menglin Xu et al.   Scientific Reports

TheSalmonellaeffectors SseF and SseG inhibit Rab1A-mediated autophagy to facilitate intracellular bacterial survival and replication

(2018) Zhao-Zhong Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mycobacterium tuberculosis: An Adaptable Pathogen Associated With Multiple Human Diseases

(2018) Qiyao Chai et al.   Frontiers in Cellular and Infection Microbiology

Mycobacterium tuberculosisis protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA

(2017) Stefan Köster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterium tuberculosis PE_PGRS41 Enhances the Intracellular Survival of M. smegmatis within Macrophages Via Blocking Innate Immunity and Inhibition of Host Defense

(2017) Wanyan Deng et al.   Scientific Reports

Expression of Rab1A is upregulated in human lung cancer and associated with tumor size and T stage

(2016) Xinxin Wang et al.   Aging-US

Gerosuppression by pan-mTOR inhibitors

(2016) Olga V. Leontieva et al.   Aging-US

Mycobacterium tuberculosis EIS gene inhibits macrophage autophagy through up-regulation of IL-10 by increasing the acetylation of histone H3

(2016) Liang Duan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular basis of mycobacterial survival in macrophages

(2016) Jane Atesoh Awuh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A unique PE_PGRS protein inhibiting host cell cytosolic defenses and sustaining full virulence ofMycobacterium marinumin multiple hosts

(2016) Vipul K. Singh et al.   CELLULAR MICROBIOLOGY

TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage Homeostasis

(2016) Santosh Chauhan et al.   DEVELOPMENTAL CELL

Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47

(2016) Neeraj K. Saini et al.   Nature Microbiology

The integration of autophagy and cellular trafficking pathways via RAB GAPs

(2015) Andreas Kern et al.   Autophagy

Autophagy regulation revealed by SapM-induced block of autophagosome-lysosome fusion via binding RAB7

(2015) Dong Hu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

(2015) Robert O. Watson et al.   Cell Host & Microbe

Unique role for ATG5 in neutrophil-mediated immunopathology during M. tuberculosis infection

(2015) Jacqueline M. Kimmey et al.   NATURE

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation

(2015) Richard Lu et al.   PLoS Pathogens

Mycobacterium tuberculosis Inhibits RAB7 Recruitment to Selectively Modulate Autophagy Flux in Macrophages

(2015) Pallavi Chandra et al.   Scientific Reports

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Mammalian target of Rapamycin inhibition and mycobacterial survival are uncoupled in murine macrophages

(2014) Alfred J Zullo et al.   BMC BIOCHEMISTRY

Rab1A Is an mTORC1 Activator and a Colorectal Oncogene

(2014) Janice D. Thomas et al.   CANCER CELL

Regulation of autophagy by the Rab GTPase network

(2014) X Ao et al.   CELL DEATH AND DIFFERENTIATION

Ypt1 recruits the Atg1 kinase to the preautophagosomal structure

(2013) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bone Marrow-derived Macrophage Production

(2013) Virginie Trouplin et al.   Jove-Journal of Visualized Experiments

Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses

(2012) Na Dong et al.   CELL

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

(2012) Robert O. Watson et al.   CELL

Mycobacterial Induction of Autophagy Varies by Species and Occurs Independently of Mammalian Target of Rapamycin Inhibition

(2012) Alfred J. Zullo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

(2012) Daria Bottai et al.   MOLECULAR MICROBIOLOGY

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

(2012) E. F. Castillo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of autophagy in host defence against Mycobacterium tuberculosis infection

(2012) Mário Songane et al.   TUBERCULOSIS

Autophagy and cytokines

(2011) James Harris   CYTOKINE

Modulation of Rab GTPase function by a protein phosphocholine transferase

(2011) Shaeri Mukherjee et al.   NATURE

The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

(2011) Kristen L. Meerbrey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins

(2010) Eisuke Itakura et al.   Autophagy

Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase

(2010) Ju Huang et al.   Autophagy

The role of the Atg1/ULK1 complex in autophagy regulation

(2010) Noboru Mizushima   CURRENT OPINION IN CELL BIOLOGY

Mycobacterium tuberculosis Eis Regulates Autophagy, Inflammation, and Cell Death through Redox-dependent Signaling

(2010) Dong-Min Shin et al.   PLoS Pathogens

The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway

(2009) Y. T. Zheng et al.   JOURNAL OF IMMUNOLOGY

Mycobacterial PE, PPE and ESX clusters: novel insights into the secretion of these most unusual protein families

(2009) Daria Bottai et al.   MOLECULAR MICROBIOLOGY

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

(2009) Teresa L M Thurston et al.   NATURE IMMUNOLOGY

Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells

(2009) Chinnaswamy Jagannath et al.   NATURE MEDICINE

Evasion and subversion of antigen presentation byMycobacterium tuberculosis

(2009) A. Baena et al.   TISSUE ANTIGENS

Identifying specific protein interaction partners using quantitative mass spectrometry and bead proteomes

(2008) Laura Trinkle-Mulcahy et al.   JOURNAL OF CELL BIOLOGY