Mycobacterium tuberculosis PE_PGRS41 Enhances the Intracellular Survival of M. smegmatis within Macrophages Via Blocking Innate Immunity and Inhibition of Host Defense

TheMycobacterium tuberculosisprotein pair PE9 (Rv1088)-PE10 (Rv1089) forms heterodimers and induces macrophage apoptosis through Toll-like receptor 4

(2015) Bhavana Tiwari et al.   CELLULAR MICROBIOLOGY

Immunoregulatory functions and expression patterns of PE/PPE family members: Roles in pathogenicity and impact on anti-tuberculosis vaccine and drug design

(2015) Asma Ahmed et al.   IUBMB LIFE

Mycobacterium tuberculosisMce3E Suppresses Host Innate Immune Responses by Targeting ERK1/2 Signaling

(2015) Jie Li et al.   JOURNAL OF IMMUNOLOGY

Phylogeny to function: PE/PPE protein evolution and impact onMycobacterium tuberculosispathogenicity

(2015) S. Fishbein et al.   MOLECULAR MICROBIOLOGY

In vivo porcine lipopolysaccharide inflammation models to study immunomodulation of drugs

(2015) H. Wyns et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Deficiency of the Novel Exopolyphosphatase Rv1026/PPX2 Leads to Metabolic Downshift and Altered Cell Wall Permeability in Mycobacterium tuberculosis

(2015) Yu-Min Chuang et al.   mBio

Mycobacterium TuberculosisPPE Family Protein Rv1808 Manipulates Cytokines Profile via Co-Activation of MAPK and NF-κB Signaling Pathways

(2014) Wanyan Deng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Mycobacterium tuberculosis Rv3402c Enhances Mycobacterial Survival within Macrophages and Modulates the Host Pro-Inflammatory Cytokines Production via NF-Kappa B/ERK/p38 Signaling

(2014) Wu Li et al.   PLoS One

Insights into battles between Mycobacterium tuberculosis and macrophages

(2014) Guanghua Xu et al.   Protein & Cell

The Scavenger Protein Apoptosis Inhibitor of Macrophages (AIM) Potentiates the Antimicrobial Response against Mycobacterium tuberculosis by Enhancing Autophagy

(2013) Lucía Sanjurjo et al.   PLoS One

Macrophages in tuberculosis: friend or foe

(2013) Evelyn Guirado et al.   Seminars in Immunopathology

Protective and survival efficacies of Rv0160c protein in murine model of Mycobacterium tuberculosis

(2012) Susmita K. Singh et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Coronin-1a inhibits autophagosome formation around Mycobacterium tuberculosis-containing phagosomes and assists mycobacterial survival in macrophages

(2012) Shintaro Seto et al.   CELLULAR MICROBIOLOGY

Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation

(2012) Daria Bottai et al.   MOLECULAR MICROBIOLOGY

The Mycobacterium tuberculosis PE Proteins Rv0285 and Rv1386 Modulate Innate Immunity and Mediate Bacillary Survival in Macrophages

(2012) Bhavana Mishra Tiwari et al.   PLoS One

Phagolysosome maturation of macrophages was reduced by PE_PGRS 62 protein expressing in Mycobacterium smegmatis and induced in IFN-γ priming

(2012) Ying Huang et al.   VETERINARY MICROBIOLOGY

A comprehensive glossary of autophagy-related molecules and processes (2ndedition)

(2011) Daniel J Klionsky et al.   Autophagy

Innate Immune Recognition ofMycobacterium tuberculosis

(2011) Johanneke Kleinnijenhuis et al.   Clinical & Developmental Immunology

Contribution of efflux activity to isoniazid resistance in the Mycobacterium tuberculosis complex

(2011) Liliana Rodrigues et al.   INFECTION GENETICS AND EVOLUTION

Importance of Phagosomal Functionality for Growth Restriction of Mycobacterium tuberculosis in Primary Human Macrophages

(2011) Amanda Welin et al.   Journal of Innate Immunity

aprABC: a Mycobacterium tuberculosis complex-specific locus that modulates pH-driven adaptation to the macrophage phagosome

(2011) Robert B. Abramovitch et al.   MOLECULAR MICROBIOLOGY

Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis

(2011) S M Behar et al.   Mucosal Immunology

Role of innate cytokines in mycobacterial infection

(2011) A M Cooper et al.   Mucosal Immunology

Mycobacterium tuberculosis Rv0198c, a putative matrix metalloprotease is involved in pathogenicity

(2011) D.G. Niranjala Muttucumaru et al.   TUBERCULOSIS

IL-10 Blocks Phagosome Maturation inMycobacterium tuberculosis–Infected Human Macrophages

(2010) Seónadh O'Leary et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A comprehensive glossary of autophagy-related molecules and processes

(2010) Daniel J. Klionsky et al.   Autophagy

Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung

(2010) Paul S. Redford et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Suppression of TLR2-Induced IL-12, Reactive Oxygen Species, and Inducible Nitric Oxide Synthase Expression by Mycobacterium tuberculosis Antigens Expressed inside Macrophages during the Course of Infection

(2010) D. Gupta et al.   JOURNAL OF IMMUNOLOGY

Expression of PE_PGRS 62 protein in Mycobacterium smegmatis decrease mRNA expression of proinflammatory cytokines IL-1β, IL-6 in macrophages

(2010) Ying Huang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mycobacterial PE, PPE and ESX clusters: novel insights into the secretion of these most unusual protein families

(2009) Daria Bottai et al.   MOLECULAR MICROBIOLOGY

Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62

(2008) J-P Pursiheimo et al.   ONCOGENE