Ultrafast homomorphic encryption models enable secure outsourcing of genotype imputation

Sketching algorithms for genomic data analysis and querying in a secure enclave

(2020) Can Kockan et al.   NATURE METHODS

TFHE: Fast Fully Homomorphic Encryption Over the Torus

(2019) Ilaria Chillotti et al.   JOURNAL OF CRYPTOLOGY

Benefits and limitations of genome-wide association studies

(2019) Vivian Tam et al.   NATURE REVIEWS GENETICS

Sparse Convolutional Denoising Autoencoders for Genotype Imputation

(2019) Junjie Chen et al.   Genes

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

(2019) Madeline H. Kowalski et al.   PLoS Genetics

A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure

(2018) Yun J. Sung et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genotype Imputation from Large Reference Panels

(2018) Sayantan Das et al.   Annual Review of Genomics and Human Genetics

Are whole-exome and whole-genome sequencing approaches cost-effective? A systematic review of the literature

(2018) Katharina Schwarze et al.   GENETICS IN MEDICINE

Secure genome-wide association analysis using multiparty computation

(2018) Hyunghoon Cho et al.   NATURE BIOTECHNOLOGY

From genome-wide associations to candidate causal variants by statistical fine-mapping

(2018) Daniel J. Schaid et al.   NATURE REVIEWS GENETICS

A One-Penny Imputed Genome from Next-Generation Reference Panels

(2018) Brian L. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

DNA sequencing at 40: past, present and future

(2017) Jay Shendure et al.   NATURE

Evolving health care through personal genomics

(2017) Heidi L. Rehm   NATURE REVIEWS GENETICS

The sequence of sequencers: The history of sequencing DNA

(2016) James M. Heather et al.   GENOMICS

Reference-based phasing using the Haplotype Reference Consortium panel

(2016) Po-Ru Loh et al.   NATURE GENETICS

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

Privacy in the Genomic Era

(2015) Muhammad Naveed et al.   ACM COMPUTING SURVEYS

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

A comprehensive SNP and indel imputability database

(2013) Q. Duan et al.   BIOINFORMATICS

Imputation across genotyping arrays for genome-wide association studies: assessment of bias and a correction strategy

(2013) Eric O. Johnson et al.   HUMAN GENETICS

On Ideal Lattices and Learning with Errors over Rings

(2013) Vadim Lyubashevsky et al.   JOURNAL OF THE ACM

Evaluating empirical bounds on complex disease genetic architecture

(2013) Vineeta Agarwala et al.   NATURE GENETICS

Meta-analysis methods for genome-wide association studies and beyond

(2013) Evangelos Evangelou et al.   NATURE REVIEWS GENETICS

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

Rare and common variants: twenty arguments

(2012) Greg Gibson   NATURE REVIEWS GENETICS

Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test

(2011) Michael C. Wu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Next generation genome-wide association tool: Design and coverage of a high-throughput European-optimized SNP array

(2011) Thomas J. Hoffmann et al.   GENOMICS

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Genotype Imputation with Thousands of Genomes

(2011) Bryan Howie et al.   G3-Genes Genomes Genetics

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Genotype imputation for genome-wide association studies

(2010) Jonathan Marchini et al.   NATURE REVIEWS GENETICS

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

On Jim Watson's APOE status: genetic information is hard to hide

(2008) Dale R Nyholt et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

(2008) Jason D Cooper et al.   NATURE GENETICS