Estimating tissue iron burden: current status and future prospects

Cardiac iron overload in sickle-cell disease

(2014) Antonella Meloni et al.   AMERICAN JOURNAL OF HEMATOLOGY

R2 and R2* are equally effective in evaluating chronic response to iron chelation

(2014) John C. Wood et al.   AMERICAN JOURNAL OF HEMATOLOGY

Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients

(2014) John B. Porter et al.   BRITISH JOURNAL OF HAEMATOLOGY

Defining serum ferritin thresholds to predict clinically relevant liver iron concentrations for guiding deferasirox therapy when MRI is unavailable in patients with non-transfusion-dependent thalassaemia

(2014) Ali T. Taher et al.   BRITISH JOURNAL OF HAEMATOLOGY

mRNA regulation of cardiac iron transporters and ferritin subunits in a mouse model of iron overload

(2014) Casey J. Brewer et al.   EXPERIMENTAL HEMATOLOGY

A decisional algorithm to start iron chelation in patients with beta thalassemia

(2014) F. Danjou et al.   HAEMATOLOGICA

Use of Magnetic Resonance Imaging to Monitor Iron Overload

(2014) John C. Wood   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Identification of erythroferrone as an erythroid regulator of iron metabolism

(2014) Léon Kautz et al.   NATURE GENETICS

Tissue iron evaluation in chronically transfused children shows significant levels of iron loading at a very young age

(2013) Vasilios Berdoukas et al.   AMERICAN JOURNAL OF HEMATOLOGY

Ferritin trends do not predict changes in total body iron in patients with transfusional iron overload

(2013) Mammen Puliyel et al.   AMERICAN JOURNAL OF HEMATOLOGY

The use of appropriate calibration curves corrects for systematic differences in liver R2* values measured using different software packages

(2013) Antonella Meloni et al.   BRITISH JOURNAL OF HAEMATOLOGY

Cardiovascular Function and Treatment in β-Thalassemia Major

(2013) Dudley J. Pennell et al.   CIRCULATION

In vivo comparison of myocardial T1 with T2 and T2* in thalassaemia major

(2013) Yanqiu Feng et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Liver disease in adult transfusion-dependent beta-thalassaemic patients: investigating the role of iron overload and chronic HCV infection

(2013) Dimitrios Kountouras et al.   LIVER INTERNATIONAL

Multicenter validation of spin-density projection-assisted R2-MRI for the noninvasive measurement of liver iron concentration

(2013) Tim G. St Pierre et al.   MAGNETIC RESONANCE IN MEDICINE

Increased Risk of Death From Iron Overload Among 422 Treated Probands With HFE Hemochromatosis and Serum Levels of Ferritin Greater Than 1000 μg/L at Diagnosis

(2012) James C. Barton et al.   Clinical Gastroenterology and Hepatology

Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats

(2012) Casey Brewer et al.   EXPERIMENTAL HEMATOLOGY

Pancreatic iron and glucose dysregulation in thalassemia major

(2011) Leila J. Noetzli et al.   AMERICAN JOURNAL OF HEMATOLOGY

Pituitary iron and volume predict hypogonadism in transfusional iron overload

(2011) Leila J. Noetzli et al.   AMERICAN JOURNAL OF HEMATOLOGY

Pituitary Iron and Volume Imaging in Healthy Controls

(2011) L.J. Noetzli et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Quantitative computed tomography assessment of transfusional iron overload

(2011) John C. Wood et al.   BRITISH JOURNAL OF HAEMATOLOGY

On T2* Magnetic Resonance and Cardiac Iron

(2011) John-Paul Carpenter et al.   CIRCULATION

Relationship between labile plasma iron, liver iron concentration and cardiac response in a deferasirox monotherapy trial

(2011) J. C. Wood et al.   HAEMATOLOGICA

The role of endocytic pathways in cellular uptake of plasma non-transferrin iron

(2011) Y.-S. Sohn et al.   HAEMATOLOGICA

Elevated liver iron concentration is a marker of increased morbidity in patients with   thalassemia intermedia

(2011) K. M. Musallam et al.   HAEMATOLOGICA

Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice

(2011) Elena Corradini et al.   HEPATOLOGY

Serum ferritin is an independent predictor of histologic severity and advanced fibrosis in patients with nonalcoholic fatty liver disease

(2011) Kris V. Kowdley et al.   HEPATOLOGY

Measurement of liver iron overload: Noninvasive calibration of MRI-R2* by magnetic iron detector susceptometer

(2011) B. Gianesin et al.   MAGNETIC RESONANCE IN MEDICINE

Association of projected transfusional iron burden with treatment intensity in childhood cancer survivors

(2011) Kathleen S. Ruccione et al.   PEDIATRIC BLOOD & CANCER

The effect of deferasirox on cardiac iron in thalassemia major: impact of total body iron stores

(2010) J. C. Wood et al.   BLOOD

Iron overload indices rise linearly with transfusion rate in patients with sickle cell disease

(2010) A. Inati et al.   BLOOD

Needle liver biopsy in thalassaemia: analyses of diagnostic accuracy and safety in 1184 consecutive biopsies

(2010) Emanuele Angelucci et al.   BRITISH JOURNAL OF HAEMATOLOGY

Relaxivity-iron calibration in hepatic iron overload: Probing underlying biophysical mechanisms using a Monte Carlo model

(2010) Nilesh R. Ghugre et al.   MAGNETIC RESONANCE IN MEDICINE

Regional and global pancreatic T*2 MRI for iron overload assessment in a large cohort of healthy subjects: Normal values and correlation with age and gender

(2010) Gennaro Restaino et al.   MAGNETIC RESONANCE IN MEDICINE

Rapid monitoring of iron-chelating therapy in thalassemia major by a new cardiovascular MR measure: the reduced transverse relaxation rate

(2010) Daniel Kim et al.   NMR IN BIOMEDICINE

Nutritional deficiencies in iron overloaded patients with hemoglobinopathies

(2009) Susan Claster et al.   AMERICAN JOURNAL OF HEMATOLOGY

Absence of cardiac siderosis despite hepatic iron overload in Italian patients with thalassemia intermedia: an MRI T2* study

(2009) Alberto Roghi et al.   ANNALS OF HEMATOLOGY

Efficacy of deferasirox in reducing and preventing cardiac iron overload in  -thalassemia

(2009) D. J. Pennell et al.   BLOOD

R2* magnetic resonance imaging of the liver in patients with iron overload

(2009) J. S. Hankins et al.   BLOOD

Pancreatic iron loading predicts cardiac iron loading in thalassemia major

(2009) L. J. Noetzli et al.   BLOOD

Daily labile plasma iron as an indicator of chelator activity inThalassaemia majorpatients

(2009) Giuliana Zanninelli et al.   BRITISH JOURNAL OF HAEMATOLOGY

Normalisation of total body iron load with very intensive combined chelation reverses cardiac and endocrine complications of thalassaemia major

(2009) Kallistheni Farmaki et al.   BRITISH JOURNAL OF HAEMATOLOGY

History and Current Impact of Cardiac Magnetic Resonance Imaging on the Management of Iron Overload

(2009) John C. Wood   CIRCULATION

Cardiac T2* Magnetic Resonance for Prediction of Cardiac Complications in Thalassemia Major

(2009) P. Kirk et al.   CIRCULATION

High nontransferrin bound iron levels and heart disease in thalassemia major

(2008) Antonio Piga et al.   AMERICAN JOURNAL OF HEMATOLOGY

Longitudinal analysis of heart and liver iron in thalassemia major

(2008) L. J. Noetzli et al.   BLOOD

Cardiac iron across different transfusion-dependent diseases

(2008) John C. Wood   BLOOD REVIEWS

On usingT2to assess extrinsic magnetic field inhomogeneity effects onT2* measurements in myocardial siderosis in thalassemia

(2008) Taigang He et al.   MAGNETIC RESONANCE IN MEDICINE

Effect of transfusional iron intake on response to chelation therapy in -thalassemia major

(2007) A. R. Cohen et al.   BLOOD