Plasmacytoid Dendritic Cells as a New Therapeutic Target for Autoimmune Pancreatitis and IgG4-Related Disease

SARS-CoV-2 induces human plasmacytoid predendritic cell diversification via UNC93B and IRAK4

(2021) Fanny Onodi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Psoriasis

(2021) Christopher E M Griffiths et al.   LANCET

Activation of interferon regulatory factor 7 in plasmacytoid dendritic cells promotes experimental autoimmune pancreatitis

(2020) Kosuke Minaga et al.   JOURNAL OF GASTROENTEROLOGY

Gut microbiome alterations in type 1 autoimmune pancreatitis after induction of remission by prednisolone

(2020) K. Kamata et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Identification of serum IFN-α and IL-33 as novel biomarkers for type 1 autoimmune pancreatitis and IgG4-related disease

(2020) Kosuke Minaga et al.   Scientific Reports

Plasmacytoid Dendritic Cells: Development, Regulation, and Function

(2019) Boris Reizis   IMMUNITY

Novel paradigms in systemic lupus erythematosus

(2019) Thomas Dörner et al.   LANCET

Management strategies and future directions for systemic lupus erythematosus in adults

(2019) Laura Durcan et al.   LANCET

Activated M2 macrophage contributes to the pathogenesis of IgG4‐related disease via TLR 7/ IL ‐33 signaling

(2019) Noriko Ishiguro et al.   Arthritis & Rheumatology

Psoriasis biologics: a new era of choice

(2019) Satveer K Mahil et al.   LANCET

Proof-of-concept clinical trial of etokimab shows a key role for IL-33 in atopic dermatitis pathogenesis

(2019) Yi-Ling Chen et al.   Science Translational Medicine

Trial of Anifrolumab in Active Systemic Lupus Erythematosus

(2019) Eric F. Morand et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation and role of the transcription factor IRF5 in innate immune responses and systemic lupus erythematosus

(2018) Tatsuma Ban et al.   INTERNATIONAL IMMUNOLOGY

Do Type I Interferons Link Systemic Autoimmunities and Metabolic Syndrome in a Pathogenetic Continuum?

(2018) Dipyaman Ganguly   TRENDS IN IMMUNOLOGY

Mechanistic Insights into Autoimmune Pancreatitis and IgG4-Related Disease

(2018) Tomohiro Watanabe et al.   TRENDS IN IMMUNOLOGY

Detection of interferon alpha protein reveals differential levels and cellular sources in disease

(2017) Mathieu P. Rodero et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic Fibro-Inflammatory Responses in Autoimmune Pancreatitis Depend on IFN-α and IL-33 Produced by Plasmacytoid Dendritic Cells

(2017) Tomohiro Watanabe et al.   JOURNAL OF IMMUNOLOGY

Type I interferon–mediated autoimmune diseases: pathogenesis, diagnosis and targeted therapy

(2017) Antonios Psarras et al.   RHEUMATOLOGY

Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus

(2017) Richard Furie et al.   Arthritis & Rheumatology

Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease

(2017) Sachiko Furukawa et al.   Scientific Reports

Sifalimumab, an anti-interferon-α monoclonal antibody, in moderate to severe systemic lupus erythematosus: a randomised, double-blind, placebo-controlled study

(2016) Munther Khamashta et al.   ANNALS OF THE RHEUMATIC DISEASES

Oxidized mitochondrial nucleoids released by neutrophils drive type I interferon production in human lupus

(2016) Simone Caielli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The association of novel IL-33 polymorphisms with sIL-33 and risk of systemic lupus erythematosus

(2016) Jing Guo et al.   MOLECULAR IMMUNOLOGY

Nucleotide-binding oligomerization domain 1 acts in concert with the cholecystokinin receptor agonist, cerulein, to induce IL-33-dependent chronic pancreatitis

(2016) T Watanabe et al.   Mucosal Immunology

Immunopathogenesis of pancreatitis

(2016) T Watanabe et al.   Mucosal Immunology

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

(2016) Christian Lood et al.   NATURE MEDICINE

Preferential M2 macrophages contribute to fibrosis in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz's disease

(2015) Sachiko Furukawa et al.   CLINICAL IMMUNOLOGY

Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme

(2015) Inna S. Afonina et al.   IMMUNITY

Plasmacytoid Dendritic Cell Activation and IFN-α Production Are Prominent Features of Murine Autoimmune Pancreatitis and Human IgG4-Related Autoimmune Pancreatitis

(2015) Yasuyuki Arai et al.   JOURNAL OF IMMUNOLOGY

IgG4-related disease

(2015) Terumi Kamisawa et al.   LANCET

Potential involvement of the IL-33–ST2 axis in the pathogenesis of primary Sjögren's syndrome

(2014) Ahmad Awada et al.   ANNALS OF THE RHEUMATIC DISEASES

Specific roles for dendritic cell subsets during initiation and progression of psoriasis

(2014) E. Glitzner et al.   EMBO Molecular Medicine

Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model

(2014) Sarah L. Rowland et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus

(2014) Vanja Sisirak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of plasmacytoid dendritic cell subsets in allergic asthma

(2013) H. Maazi et al.   ALLERGY

Recent advances in autoimmune pancreatitis: type 1 and type 2

(2013) Terumi Kamisawa et al.   GUT

Anti-IFN- /  Receptor Antibody Treatment Ameliorates Disease in Lupus-Predisposed Mice

(2012) R. Baccala et al.   JOURNAL OF IMMUNOLOGY

Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes

(2012) Julien Diana et al.   NATURE MEDICINE

IgG4-Related Disease

(2012) John H. Stone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus

(2011) G. S. Garcia-Romo et al.   Science Translational Medicine

The type I interferon system in the etiopathogenesis of autoimmune diseases

(2011) Lars Rönnblom   UPSALA JOURNAL OF MEDICAL SCIENCES

Rituximab therapy leads to rapid decline of serum IgG4 levels and prompt clinical improvement in IgG4-related systemic disease

(2010) Arezou Khosroshahi et al.   ARTHRITIS AND RHEUMATISM

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway

(2010) Tomohiro Watanabe et al.   JOURNAL OF CLINICAL INVESTIGATION

Sequential Role of Plasmacytoid Dendritic Cells and Regulatory T Cells in Oral Tolerance

(2009) Bertrand Dubois et al.   GASTROENTEROLOGY

Plasmacytoid Dendritic Cells Are Proportionally Expanded at Diagnosis of Type 1 Diabetes and Enhance Islet Autoantigen Presentation to T-Cells Through Immune Complex Capture

(2008) J. S. Allen et al.   DIABETES