A CD10‐OGP Membrane Peptolytic Signaling Axis in Fibroblasts Regulates Lipid Metabolism of Cancer Stem Cells via SCD1

Application of a Pseudotargeted MS Method for the Quantification of Glycated Hemoglobin for the Improved Diagnosis of Diabetes Mellitus

(2020) Weifeng Li et al.   ANALYTICAL CHEMISTRY

Lipid desaturation-associated endoplasmic reticulum stress regulates MYCN gene expression in hepatocellular carcinoma cells

(2020) Xian-Yang Qin et al.   Cell Death & Disease

CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint

(2020) Miao Yu et al.   Nature Communications

Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity

(2020) Yiwen Lu et al.   CELL

Wnt/β-catenin signaling regulates adipose tissue lipogenesis and adipocyte-specific loss is rigorously defended by neighboring stromal-vascular cells

(2020) Devika P. Bagchi et al.   Molecular Metabolism

Genome sequence and transcriptomic profiles of a marine bacterium, Pseudoalteromonas agarivorans Hao 2018

(2019) Kai Shan et al.   Scientific Data

TagGraph reveals vast protein modification landscapes from large tandem mass spectrometry datasets

(2019) Arun Devabhaktuni et al.   NATURE BIOTECHNOLOGY

The EMBL-EBI search and sequence analysis tools APIs in 2019

(2019) Fábio Madeira et al.   NUCLEIC ACIDS RESEARCH

Metabolic reprogramming and redox adaptation in sorafenib-resistant leukemia cells: detected by untargeted metabolomics and stable isotope tracing analysis

(2019) Xin You et al.   Cancer Communications

Effects of 2,3′,4,4′5-pentachlorobiphenyl exposure during pregnancy on epigenetic imprinting and maturation of offspring’s oocytes in mice

(2019) Qi-Long He et al.   ARCHIVES OF TOXICOLOGY

Characterization of the stemness potency of mammospheres isolated from the breast cancer cell lines

(2019) Saghar Yousefnia et al.   TUMOR BIOLOGY

Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer

(2018) Ana Costa et al.   CANCER CELL

LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody–Drug Conjugates

(2018) James W. Purcell et al.   CANCER RESEARCH

CD10 + GPR77 + Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness

(2018) Shicheng Su et al.   CELL

A peek into cancer-associated fibroblasts: origins, functions and translational impact

(2018) Valerie S. LeBleu et al.   Disease Models & Mechanisms

Hypoxia induces miR-153 through the IRE1α-XBP1 pathway to fine tune the HIF1α/VEGFA axis in breast cancer angiogenesis

(2018) Huichun Liang et al.   ONCOGENE

Cancer-associated fibroblasts induce antigen-specific deletion of CD8+ T Cells to protect tumour cells

(2018) Matthew A. Lakins et al.   Nature Communications

Immune Checkpoint Inhibition Overcomes ADCP-Induced Immunosuppression by Macrophages

(2018) Shicheng Su et al.   CELL

Deletion of Stearoyl-CoA Desaturase-1 From the Intestinal Epithelium Promotes Inflammation and Tumorigenesis, Reversed by Dietary Oleate

(2018) Simon Ducheix et al.   GASTROENTEROLOGY

Toward understanding cancer stem cell heterogeneity in the tumor microenvironment

(2018) Federico Bocci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergistic Effects of NOTCH/γ-Secretase Inhibition and Standard of Care Treatment Modalities in Non-small Cell Lung Cancer Cells

(2018) Venus Sosa Iglesias et al.   Frontiers in Oncology

Changes of Cerebrospinal Fluid Peptides due to Tauopathy

(2017) Petra Majerova et al.   JOURNAL OF ALZHEIMERS DISEASE

Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

(2017) Daniel Öhlund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multiplexed Temporal Quantification of the Exercise-regulated Plasma Peptidome

(2017) Benjamin L. Parker et al.   MOLECULAR & CELLULAR PROTEOMICS

Gamma Secretase Inhibition by BMS-906024 Enhances Efficacy of Paclitaxel in Lung Adenocarcinoma

(2017) Katherine M. Morgan et al.   MOLECULAR CANCER THERAPEUTICS

Cancer stem cells revisited

(2017) Eduard Batlle et al.   NATURE MEDICINE

Metformin suppresses triple-negative breast cancer stem cells by targeting KLF5 for degradation

(2017) Peiguo Shi et al.   Cell Discovery

Numb is involved in the non-random segregation of subcellular vesicles in colorectal cancer stem cells

(2016) Wei-Lun Hwang et al.   CELL CYCLE

Dll4 Inhibition plus Aflibercept Markedly Reduces Ovarian Tumor Growth

(2016) Jie Huang et al.   MOLECULAR CANCER THERAPEUTICS

Hypoxic and Reoxygenated Microenvironment: Stemness and Differentiation State in Glioblastoma

(2016) Mariana Maier Gaelzer et al.   MOLECULAR NEUROBIOLOGY

Ionic immune suppression within the tumour microenvironment limits T cell effector function

(2016) Robert Eil et al.   NATURE

CD44hiCD24lo mammosphere-forming cells from primary breast cancer display resistance to multiple chemotherapeutic drugs

(2016) PING JI et al.   ONCOLOGY REPORTS

Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions

(2016) Hui Zhang et al.   Cell Reports

A Cytoplasmic NF-κB Interacting Long Noncoding RNA Blocks IκB Phosphorylation and Suppresses Breast Cancer Metastasis

(2015) Bodu Liu et al.   CANCER CELL

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses

(2015) Ping-Chih Ho et al.   CELL

The Cancer Stem Cell Niche: How Essential Is the Niche in Regulating Stemness of Tumor Cells?

(2015) Vicki Plaks et al.   Cell Stem Cell

Randomized Phase Ib/II Study of Gemcitabine Plus Placebo or Vismodegib, a Hedgehog Pathway Inhibitor, in Patients With Metastatic Pancreatic Cancer

(2015) Daniel V.T. Catenacci et al.   JOURNAL OF CLINICAL ONCOLOGY

IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis

(2015) Charles K. Pallangyo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Unsaturated Fatty Acids Stimulate Tumor Growth through Stabilization of β-Catenin

(2015) Hyeonwoo Kim et al.   Cell Reports

Development of a clickable bimodal fluorescent/PET probe for in vivo imaging

(2015) Andreas Paulus et al.   EJNMMI Research

CD10 as a novel marker of therapeutic resistance and cancer stem cells in head and neck squamous cell carcinoma

(2014) T Fukusumi et al.   BRITISH JOURNAL OF CANCER

A Positive Feedback Loop between Mesenchymal-like Cancer Cells and Macrophages Is Essential to Breast Cancer Metastasis

(2014) Shicheng Su et al.   CANCER CELL

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

(2014) Berna C. Özdemir et al.   CANCER CELL

Metastatic Stem Cells: Sources, Niches, and Vital Pathways

(2014) Thordur Oskarsson et al.   Cell Stem Cell

A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1

(2014) T. Justin Rettenmaier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid Metabolism Greases the Stem Cell Engine

(2013) Clifford D.L. Folmes et al.   Cell Metabolism

The small peptide OGP(10-14) reduces proliferation and induces differentiation of TPO-primed M07-e cells through RhoA/TGFbeta1/SFK pathway

(2013) Barbara Battolla et al.   MEDICAL SCIENCE MONITOR

Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer

(2013) C. Feig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Near-infrared fluorescence imaging of gastrin releasing peptide receptor targeting in prostate cancer lymph node metastases

(2013) Quan-Yu Cai et al.   PROSTATE

Stearoyl CoA Desaturase Is Required to Produce Active, Lipid-Modified Wnt Proteins

(2013) Jessica Rios-Esteves et al.   Cell Reports

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

Cancer Stem Cells: Current Status and Evolving Complexities

(2012) Jane E. Visvader et al.   Cell Stem Cell

Preclinical Analysis of the  -Secretase Inhibitor PF-03084014 in Combination with Glucocorticoids in T-cell Acute Lymphoblastic Leukemia

(2012) J. B. Samon et al.   MOLECULAR CANCER THERAPEUTICS

Peptidome Analysis of Cerebrospinal Fluid by LC-MALDI MS

(2012) Mikko Hölttä et al.   PLoS One

Prolonged mammosphere culture of MCF-7 cells induces an EMT and repression of the estrogen receptor by microRNAs

(2011) I. K. Guttilla et al.   BREAST CANCER RESEARCH AND TREATMENT

The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis

(2011) Md. Hasan Zaki et al.   CANCER CELL

Epidermal Growth Factor-Like Domain 7 Is a Novel Inhibitor of Neutrophil Adhesion to Coronary Artery Endothelial Cells Injured by Calcineurin Inhibition

(2011) M. V. Badiwala et al.   CIRCULATION

Identification of cancer stem cells in vincristine preconditioned SGC7901 gastric cancer cell line

(2011) Zengfu Xue et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Breast cancer stem cells, cytokine networks, and the tumor microenvironment

(2011) Hasan Korkaya et al.   JOURNAL OF CLINICAL INVESTIGATION

Synthetic osteogenic growth peptide promotes differentiation of human bone marrow mesenchymal stem cells to osteoblasts via RhoA/ROCK pathway

(2011) Zixian Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

A New Method for Isolation of Interstitial Fluid from Human Solid Tumors Applied to Proteomic Analysis of Ovarian Carcinoma Tissue

(2011) Hanne Haslene-Hox et al.   PLoS One

CD10-bearing fibroblasts may inhibit skin inflammation by down-modulating substance P

(2010) Lining Xie et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Affinity Peptide for Targeted Detection of Dysplasia in Barrett's Esophagus

(2010) Meng Li et al.   GASTROENTEROLOGY

Oncocin (VDKPPYLPRPRPPRRIYNR-NH2): A Novel Antibacterial Peptide Optimized against Gram-Negative Human Pathogens

(2010) Daniel Knappe et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rapamycin Regulates Stearoyl CoA Desaturase 1 Expression in Breast Cancer

(2010) D. Luyimbazi et al.   MOLECULAR CANCER THERAPEUTICS

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

(2010) Louis Vermeulen et al.   NATURE CELL BIOLOGY

Metabolic oxidation regulates embryonic stem cell differentiation

(2010) Oscar Yanes et al.   Nature Chemical Biology

Production of an antigenic peptide by insulin-degrading enzyme

(2010) Nicolas Parmentier et al.   NATURE IMMUNOLOGY

HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage

(2009) Luca Vanella et al.   BONE

The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells

(2009) Angelo Cicalese et al.   CELL

PD-1 Ligand Expression by Human Colonic Myofibroblasts/Fibroblasts Regulates CD4+ T-Cell Activity

(2008) Irina V. Pinchuk et al.   GASTROENTEROLOGY