Membrane-Permeable Antibacterial Enzyme against Multidrug-Resistant Acinetobacter baumannii

A Novel Acinetobacter baumannii Bacteriophage Endolysin LysAB54 With High Antibacterial Activity Against Multiple Gram-Negative Microbes

(2021) Fazal Mehmood Khan et al.   Frontiers in Cellular and Infection Microbiology

The Advantages and Challenges of Using Endolysins in a Clinical Setting

(2021) Ellen Murray et al.   Viruses-Basel

Resistance of Gram-Negative Bacteria to Current Antibacterial Agents and Approaches to Resolve It

(2020) Zeinab Breijyeh et al.   MOLECULES

In vitro and in vivo efficacy of combinations of colistin and different endolysins against clinical strains of multi-drug resistant pathogens

(2020) Lucia Blasco et al.   Scientific Reports

Multidrug Resistance (MDR) and Collateral Sensitivity in Bacteria, with Special Attention to Genetic and Evolutionary Aspects and to the Perspectives of Antimicrobial Peptides—A Review

(2020) András Fodor et al.   Pathogens

Lysins breaking down the walls of Gram-negative bacteria, no longer a no-go

(2020) Diana Gutiérrez et al.   CURRENT OPINION IN BIOTECHNOLOGY

The Capsule Depolymerase Dpo48 Rescues Galleria mellonella and Mice From Acinetobacter baumannii Systemic Infections

(2019) Yannan Liu et al.   Frontiers in Microbiology

The Preclinical and Clinical Progress of Bacteriophages and Their Lytic Enzymes: The Parts are Easier than the Whole

(2019) Karim Abdelkader et al.   Viruses-Basel

The Antistaphylococcal Lysin, CF-301, Activates Key Host Factors in Human Blood To Potentiate Methicillin-Resistant Staphylococcus aureus Bacteriolysis

(2019) Chiara Indiani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Isolation of phage lysins that effectively kill Pseudomonas aeruginosa in mouse models of lung and skin infection

(2019) Assaf Raz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Preparation and characterization of endolysin-containing liposomes and evaluation of their antimicrobial activities against gram-negative bacteria

(2019) Jaewoo Bai et al.   ENZYME AND MICROBIAL TECHNOLOGY

Endolysins as emerging alternative therapeutic agent to counter drug resistant infections.

(2019) Vijay Singh Gondil et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Dendronized Silver Nanoparticles as Bacterial Membrane Permeabilizers and Their Interactions With P. aeruginosa Lipopolysaccharides, Lysozymes, and Phage-Derived Endolysins

(2019) Karol Ciepluch et al.   Frontiers in Microbiology

Synthetic biology of modular endolysins

(2018) Hans Gerstmans et al.   BIOTECHNOLOGY ADVANCES

Bacterial biofilm and associated infections

(2018) Muhsin Jamal et al.   Journal of the Chinese Medical Association

In vitro characterization of PlyE146, a novel phage lysin that targets Gram-negative bacteria

(2018) Yu Larpin et al.   PLoS One

Phage Lysins for Fighting Bacterial Respiratory Infections: A New Generation of Antimicrobials

(2018) Roberto Vázquez et al.   Frontiers in Immunology

A Novel Antimicrobial Endolysin, LysPA26, against Pseudomonas aeruginosa

(2017) Mingquan Guo et al.   Frontiers in Microbiology

Comparative Analysis of the Bacterial Membrane Disruption Effect of Two Natural Plant Antimicrobial Peptides

(2017) Attila Farkas et al.   Frontiers in Microbiology

Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii

(2016) Valerie Defraine et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel Engineered Peptides of a Phage Lysin as Effective Antimicrobials against Multidrug-Resistant Acinetobacter baumannii

(2016) Mya Thandar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Reflecting on the final report of the O'Neill Review on Antimicrobial Resistance

(2016) Laura J V Piddock   LANCET INFECTIOUS DISEASES

Exogenous Lytic Activity of SPN9CC Endolysin Against Gram-Negative Bacteria

(2016) Jeong-A Lim et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Breaking barriers: expansion of the use of endolysins as novel antibacterials against Gram-negative bacteria

(2015) Yves Briers et al.   Future Microbiology

In vivo activity of daptomycin/colistin combination therapy in a Galleria mellonella model of Acinetobacter baumannii infection

(2015) Haifei Yang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Antibacterial Activity of a Novel Peptide-Modified Lysin Against Acinetobacter baumannii and Pseudomonas aeruginosa

(2015) Hang Yang et al.   Frontiers in Microbiology

Art-175 Is a Highly Efficient Antibacterial against Multidrug-Resistant Strains and Persisters of Pseudomonas aeruginosa

(2014) Yves Briers et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibacterial properties of Acinetobacter baumanniiphage Abp1 endolysin (PlyAB1)

(2014) Guangtao Huang et al.   BMC INFECTIOUS DISEASES

Characterization, sequencing and comparative genomic analysis of vB_AbaM-IME-AB2, a novel lytic bacteriophage that infects multidrug-resistant Acinetobacter baumannii clinical isolates

(2014) Fan Peng et al.   BMC MICROBIOLOGY

Structure of bacteriophage SPN1S endolysin reveals an unusual two-module fold for the peptidoglycan lytic and binding activity

(2014) Yangshin Park et al.   MOLECULAR MICROBIOLOGY

A Thermostable Salmonella Phage Endolysin, Lys68, with Broad Bactericidal Properties against Gram-Negative Pathogens in Presence of Weak Acids

(2014) Hugo Oliveira et al.   PLoS One

Engineered Endolysin-Based "Artilysins" To Combat Multidrug-Resistant Gram-Negative Pathogens

(2014) Y. Briers et al.   mBio

Combination Therapy With Lysin CF-301 and Antibiotic Is Superior to Antibiotic Alone for Treating Methicillin-Resistant Staphylococcus aureus–Induced Murine Bacteremia

(2013) Raymond Schuch et al.   JOURNAL OF INFECTIOUS DISEASES

Characterization of Flavin-Based Fluorescent Proteins: An Emerging Class of Fluorescent Reporters

(2013) Arnab Mukherjee et al.   PLoS One

Bacteriophage endolysins as novel antimicrobials

(2012) Mathias Schmelcher et al.   Future Microbiology

Antibacterial activity of Acinetobacter baumannii phage ϕAB2 endolysin (LysAB2) against both Gram-positive and Gram-negative bacteria

(2011) Meng-Jiun Lai et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Lag Phase Is a Distinct Growth Phase That Prepares Bacteria for Exponential Growth and Involves Transient Metal Accumulation

(2011) M. D. Rolfe et al.   JOURNAL OF BACTERIOLOGY

From the regulation of peptidoglycan synthesis to bacterial growth and morphology

(2011) Athanasios Typas et al.   NATURE REVIEWS MICROBIOLOGY

Galleria mellonella as a Model System To Study Acinetobacter baumannii Pathogenesis and Therapeutics

(2009) A. Y. Peleg et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Current Perspectives on Stability of Protein Drug Products during Formulation, Fill and Finish Operations

(2008) N. Rathore et al.   BIOTECHNOLOGY PROGRESS