Human embryo research, stem cell-derived embryo models and in vitro gametogenesis: Considerations leading to the revised ISSCR guidelines

Naive stem cell blastocyst model captures human embryo lineage segregation

(2021) Ayaka Yanagida et al.   Cell Stem Cell

Modelling human blastocysts by reprogramming fibroblasts into iBlastoids

(2021) Xiaodong Liu et al.   NATURE

Blastocyst-like structures generated from human pluripotent stem cells

(2021) Leqian Yu et al.   NATURE

Toward Guidelines for Research on Human Embryo Models Formed from Stem Cells

(2020) Insoo Hyun et al.   Stem Cell Reports

The moral status of human embryo‐like structures: potentiality matters?

(2020) Tsutomu Sawai et al.   EMBO REPORTS

Modelling human embryogenesis: embryo-like structures spark ethical and policy debate

(2020) Ana M Pereira Daoud et al.   HUMAN REPRODUCTION UPDATE

An in vitro model of early anteroposterior organization during human development

(2020) Naomi Moris et al.   NATURE

Human Embryogenesis: A Comparative Perspective

(2020) Claudia Gerri et al.   Annual Review of Cell and Developmental Biology

National human embryo and embryoid research policies: a survey of 22 top research-intensive countries

(2020) Kirstin RW Matthews et al.   Regenerative Medicine

Future developments: In vitro growth (IVG) of human ovarian follicles

(2019) Evelyn E Telfer   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA

Controlled modelling of human epiblast and amnion development using stem cells

(2019) Yi Zheng et al.   NATURE

Self-organizing neuruloids model developmental aspects of Huntington’s disease in the ectodermal compartment

(2019) Tomomi Haremaki et al.   NATURE BIOTECHNOLOGY

Induced 2C Expression and Implantation-Competent Blastocyst-like Cysts from Primed Pluripotent Stem Cells

(2019) Cody Kime et al.   Stem Cell Reports

Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures

(2019) Ronghui Li et al.   CELL

In vitro culture of cynomolgus monkey embryos beyond early gastrulation

(2019) Huaixiao Ma et al.   SCIENCE

Dissecting primate early post-implantation development using long-term in vitro embryo culture

(2019) Yuyu Niu et al.   SCIENCE

Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid

(2019) Berna Sozen et al.   DEVELOPMENTAL CELL

Blastocyst-like structures generated solely from stem cells

(2018) Nicolas C. Rivron et al.   NATURE

Generation of human oogonia from induced pluripotent stem cells in vitro

(2018) Chika Yamashiro et al.   SCIENCE

Debate ethics of embryo models from stem cells

(2018) Nicolas Rivron et al.   NATURE

Single-cell transcriptome of early embryos and cultured embryonic stem cells of cynomolgus monkeys

(2017) Tomonori Nakamura et al.   Scientific Data

Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro

(2016) Quan Zhou et al.   Cell Stem Cell

The Germ Cell Fate of Cynomolgus Monkeys Is Specified in the Nascent Amnion

(2016) Kotaro Sasaki et al.   DEVELOPMENTAL CELL

Embryology policy: Revisit the 14-day rule

(2016) Insoo Hyun et al.   NATURE

Self-organization of the in vitro attached human embryo

(2016) Alessia Deglincerti et al.   NATURE

Reconstitution in vitro of the entire cycle of the mouse female germ line

(2016) Orie Hikabe et al.   NATURE

Self-organization of the human embryo in the absence of maternal tissues

(2016) Marta N. Shahbazi et al.   NATURE CELL BIOLOGY

Complete in vitro generation of fertile oocytes from mouse primordial germ cells

(2016) Kanako Morohaku et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vitro Derivation and Propagation of Spermatogonial Stem Cell Activity from Mouse Pluripotent Stem Cells

(2016) Yukiko Ishikura et al.   Cell Reports

SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

(2015) Naoko Irie et al.   CELL

Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells

(2015) Kotaro Sasaki et al.   Cell Stem Cell

Neural Tube Defects

(2014) Nicholas D.E. Greene et al.   Annual Review of Neuroscience

Symmetry breaking, germ layer specification and axial organisation in aggregates of mouse embryonic stem cells

(2014) S. C. van den Brink et al.   DEVELOPMENT

A method to recapitulate early embryonic spatial patterning in human embryonic stem cells

(2014) Aryeh Warmflash et al.   NATURE METHODS

Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-like Cells in Mice

(2012) K. Hayashi et al.   SCIENCE

Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells

(2011) Katsuhiko Hayashi et al.   CELL

In vitro production of functional sperm in cultured neonatal mouse testes

(2011) Takuya Sato et al.   NATURE

In vitro production of fertile sperm from murine spermatogonial stem cell lines

(2011) Takuya Sato et al.   Nature Communications

A Signaling Principle for the Specification of the Germ Cell Lineage in Mice

(2009) Yasuhide Ohinata et al.   CELL

Effect of In Utero and Early-Life Conditions on Adult Health and Disease

(2008) Peter D. Gluckman et al.   NEW ENGLAND JOURNAL OF MEDICINE