Altered Expression of DAAM1 and PREP Induced by Cadmium Toxicity Is Counteracted by Melatonin in the Rat Testis

A review on Cadmium Exposure in the Population and Intervention Strategies Against Cadmium Toxicity

(2021) Mei Wang et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Molecular Mechanisms of Melatonin-Mediated Cell Protection and Signaling in Health and Disease

(2021) Dalia M. Kopustinskiene et al.   Pharmaceutics

Preliminary Investigation on the Ameliorative Role Exerted by D-Aspartic Acid in Counteracting Ethane Dimethane Sulfonate (EDS) Toxicity in the Rat Testis

(2021) Massimo Venditti et al.   Animals

The Importance of Oxidative Stress in Determining the Functionality of Mammalian Spermatozoa: A Two-Edged Sword

(2020) Robert J. Aitken et al.   Antioxidants

Cadmium‐induced toxicity increases prolyl endopeptidase (PREP) expression in the rat testis

(2020) Massimo Venditti et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Toxicological Effects of Cadmium on Mammalian Testis

(2020) Qiqi Zhu et al.   Frontiers in Genetics

D-Aspartate Upregulates DAAM1 Protein Levels in the Rat Testis and Induces Its Localization in Spermatogonia Nucleus

(2020) Massimo Venditti et al.   Biomolecules

Downregulation of vdac2 inhibits spermatogenesis via JNK and P53 signalling in mice exposed to cadmium

(2020) Yu Fang et al.   TOXICOLOGY LETTERS

Cadmium as a testicular toxicant: A Review

(2020) Jitender Kumar Bhardwaj et al.   JOURNAL OF APPLIED TOXICOLOGY

EH domain binding protein 1-like 1 (EHBP1L1), a protein with calponin homology domain, is expressed in the rat testis

(2020) Massimo Venditti et al.   ZYGOTE

Regulation of Cell Death by Mitochondrial Transport Systems of Calcium and Bcl-2 Proteins

(2020) Natalia Naumova et al.   Membranes

Central and peripheral actions of melatonin on reproduction in seasonal and continuous breeding mammals

(2020) Russel J. Reiter et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Endocrine-Disrupting Air Pollutants and Their Effects on the Hypothalamus-Pituitary-Gonadal Axis

(2020) Elizabeth C. Plunk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

First evidence of the protective role of melatonin in counteracting cadmium toxicity in the rat ovary via the mTOR pathway

(2020) Safa Kechiche et al.   ENVIRONMENTAL POLLUTION

Prolyl oligopeptidase regulates progesterone secretion via the ERK signaling pathway in murine luteal cells

(2019) Ping Xu et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Study on PREP localization in mouse seminal vesicles and its possible involvement during regulated exocytosis

(2019) Massimo Venditti et al.   ZYGOTE

Physiological Adaptation to Simultaneous Chronic Exposure to High-Fat Diet and Dichlorodipheniletylhene (DDE) in Wistar Rat Testis

(2019) Migliaccio et al.   Cells

D-Asp upregulates PREP and GluA2/3 expressions and induces p-ERK1/2 and p-Akt in rat testis

(2019) Alessandra Santillo et al.   REPRODUCTION

Study of expression of genes potentially responsible for reduced fitness in patients with myotonic dystrophy type 1 and identification of new biomarkers of testicular function

(2019) Manuela Ergoli et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Melatonin protects bone against cadmium-induced toxicity via activation of Wnt/β-catenin signaling pathway

(2019) Latifa Knani et al.   TOXICOLOGY MECHANISMS AND METHODS

First evidence of DAAM1 localization in mouse seminal vesicles and its possible involvement during regulated exocytosis

(2018) Massimo Venditti et al.   COMPTES RENDUS BIOLOGIES

Subcellular Localization of Prolyl Endopeptidase During the First Wave of Rat Spermatogenesis and in Rat and Human Sperm

(2018) Massimo Venditti et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Prolyl oligopeptidase and its role in the organism: attention to the most promising and clinically relevant inhibitors

(2017) Katerina Babkova et al.   Future Medicinal Chemistry

Melatonin Scavenger Properties against Oxidative and Nitrosative Stress: Impact on Gamete Handling and In Vitro Embryo Production in Humans and Other Mammals

(2017) Pía Loren et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Involvement of testicular DAAM1 expression in zinc protection against cadmium-induced male rat reproductive toxicity

(2017) Marouane Chemek et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Differential Susceptibility of Germ and Leydig Cells to Cadmium-Mediated Toxicity: Impact on Testis Structure, Adiponectin Levels, and Steroidogenesis

(2017) Marli C. Cupertino et al.   Oxidative Medicine and Cellular Longevity

The environment and male reproduction: The effect of cadmium exposure on reproductive function and its implication in fertility

(2017) Cristina de Angelis et al.   REPRODUCTIVE TOXICOLOGY

Reproductive effects of cadmium on sperm function and early embryonic development in vitro

(2017) Li-lin Zhao et al.   PLoS One

First Evidence of DAAM1 Localization During the Post-Natal Development of Rat Testis and in Mammalian Sperm

(2016) Paolo Pariante et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Chronic exposures and male fertility: the impacts of environment, diet, and drug use on spermatogenesis

(2016) J. S. Gabrielsen et al.   Andrology

The Protective Effects of Melatonin Against Oxidative Stress and Inflammation Induced by Acute Cadmium Exposure in Mice Testis

(2015) Renyan Li et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Induction of DNA Damage and G2 Cell Cycle Arrest by Diepoxybutane through the Activation of the Chk1-Dependent Pathway in Mouse Germ Cells

(2015) Jianyun Dong et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Sertoli cells are the target of environmental toxicants in the testis – a mechanistic and therapeutic insight

(2015) Ying Gao et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Prolyl Endopeptidase (PREP) is Associated With Male Reproductive Functions and Gamete Physiology in Mice

(2015) Raffaele Dotolo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A unique view on male infertility around the globe

(2015) Ashok Agarwal et al.   Reproductive Biology and Endocrinology

Prothymosin alpha expression and localization during the spermatogenesis of Danio rerio

(2015) Paolo Pariante et al.   ZYGOTE

Regulation of cytoskeletal dynamics by redox signaling and oxidative stress: implications for neuronal development and trafficking

(2015) Carlos Wilson et al.   Frontiers in Cellular Neuroscience

Impact of oxidative stress on the cytoskeleton of pancreatic epithelial cells

(2014) WEI-GUO HU et al.   Experimental and Therapeutic Medicine

Actin cytoskeleton redox proteome oxidation by cadmium

(2013) Young-Mi Go et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The hypothalamic–pituitary–gonadal axis is target of cadmium toxicity. An update of recent studies and potential therapeutic approaches

(2013) Anunciación Lafuente   FOOD AND CHEMICAL TOXICOLOGY

Melatonin alleviates cadmium-induced cellular stress and germ cell apoptosis in testes

(2011) Yan-Li Ji et al.   JOURNAL OF PINEAL RESEARCH

Sequential Expression, Activity and Nuclear Localization of Prolyl Oligopeptidase Protein in the Developing Rat Brain

(2010) Mirva J. Hannula et al.   DEVELOPMENTAL NEUROSCIENCE

Prolyl endopeptidase mRNA expression in the central nervous system during rat development

(2010) N. Agirregoitia et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Cytoskeletal dynamics and spermatogenesis

(2010) P. P. Y. Lie et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Adverse Effects of Low Level Heavy Metal Exposure on Male Reproductive Function

(2010) Julia J. Wirth et al.   Systems Biology in Reproductive Medicine

Cadmium: Toxic effects on the reproductive system and the embryo

(2008) J THOMPSON et al.   REPRODUCTIVE TOXICOLOGY