Sertoli cells are the target of environmental toxicants in the testis – a mechanistic and therapeutic insight

Fascin 1 is an actin filament-bundling protein that regulates ectoplasmic specialization dynamics in the rat testis

(2014) N. Ece Gungor-Ordueri et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Oxidative stress and male reproductive health

(2014) RobertJ Aitken et al.   ASIAN JOURNAL OF ANDROLOGY

A critical review of perfluorooctanoate and perfluorooctanesulfonate exposure and cancer risk in humans

(2014) Ellen T. Chang et al.   CRITICAL REVIEWS IN TOXICOLOGY

Cadmium as a possible cause of bladder cancer: a review of accumulated evidence

(2014) Molka Feki-Tounsi et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The role of Pten/Akt signaling pathway involved in BPA-induced apoptosis of rat sertoli cells

(2014) Chengmin Wang et al.   ENVIRONMENTAL TOXICOLOGY

Specific Cx43 phosphorylation events regulate gap junction turnover in vivo

(2014) Joell L. Solan et al.   FEBS LETTERS

Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins

(2014) X. Xiao et al.   HUMAN REPRODUCTION

A Review of Molecular Events of Cadmium-Induced Carcinogenesis

(2014) Joe Luevano et al.   JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY

A Mechanism of Male Germ Cell Apoptosis Induced by Bisphenol-A and Nonylphenol Involving ADAM17 and p38 MAPK Activation

(2014) Paulina Urriola-Muñoz et al.   PLoS One

BPA-induced apoptosis of rat Sertoli cells through Fas/FasL and JNKs/p38 MAPK pathways

(2014) Suqin Qi et al.   REPRODUCTIVE TOXICOLOGY

Actin binding proteins, spermatid transport and spermiation

(2014) Xiaojing Qian et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Role of non-receptor protein tyrosine kinases in spermatid transport during spermatogenesis

(2014) H.T. Wan et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Involvement of CaM-CaMKII-ERK in bisphenol A-induced Sertoli cell apoptosis

(2014) Wenyi Qian et al.   TOXICOLOGY

Interaction of environmental contaminants with zebrafish organic anion transporting polypeptide, Oatp1d1 (Slco1d1)

(2014) Marta Popovic et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Occupational exposure to pesticides and consequences on male semen and fertility: A review

(2014) Omid Mehrpour et al.   TOXICOLOGY LETTERS

p-FAK-Tyr397 regulates spermatid adhesion in the rat testis via its effects on F-actin organization at the ectoplasmic specialization

(2013) Hin-Ting Wan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Release of Bisphenol A from Polycarbonate—A Review

(2013) Eddo J. Hoekstra et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Palladin Is a Regulator of Actin Filament Bundles at the Ectoplasmic Specialization in Adult Rat Testes

(2013) Xiaojing Qian et al.   ENDOCRINOLOGY

Perfluorooctanesulfonate (PFOS) Perturbs Male Rat Sertoli Cell Blood-Testis Barrier Function by Affecting F-Actin Organization via p-FAK-Tyr407: Anin VitroStudy

(2013) Hin-Ting Wan et al.   ENDOCRINOLOGY

Accumulation of perfluoroalkyl substances in human tissues

(2013) Francisca Pérez et al.   ENVIRONMENT INTERNATIONAL

Targeting testis-specific proteins to inhibit spermatogenesis: lesson from endocrine disrupting chemicals

(2013) HT Wan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The use of genomics, proteomics, and metabolomics in identifying biomarkers of male infertility

(2013) Jason R. Kovac et al.   FERTILITY AND STERILITY

Injury-triggered Akt phosphorylation of Cx43: a ZO-1-driven molecular switch that regulates gap junction size

(2013) C. A. Dunn et al.   JOURNAL OF CELL SCIENCE

MAP/microtubule affinity-regulating kinases, microtubule dynamics, and spermatogenesis

(2013) Elizabeth I Tang et al.   JOURNAL OF ENDOCRINOLOGY

Sertoli Cell Is a Potential Target for Perfluorooctane Sulfonate–Induced Reproductive Dysfunction in Male Mice

(2013) Lianglin Qiu et al.   TOXICOLOGICAL SCIENCES

Decline of semen quality among 10 932 males consulting for couple infertility over a 20-year period in Marseille, France

(2012) Cendrine Geoffroy-Siraudin et al.   ASIAN JOURNAL OF ANDROLOGY

Semen quality, sperm selection and hematospermia

(2012) Amichai Kilchevsky et al.   Nature Reviews Urology

Focal adhesion kinase-Tyr407 and -Tyr397 exhibit antagonistic effects on blood-testis barrier dynamics in the rat

(2012) P. P. Y. Lie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular changes induced by bisphenol-A in rat Sertoli cell culture

(2012) Yoko Izumi et al.   Systems Biology in Reproductive Medicine

Of Mice and Men (and Rats): Phthalate-Induced Fetal Testis Endocrine Disruption Is Species-Dependent

(2012) Kamin J. Johnson et al.   TOXICOLOGICAL SCIENCES

Critical evaluation of key evidence on the human health hazards of exposure to bisphenol A

(2011) J. G. Hengstler et al.   CRITICAL REVIEWS IN TOXICOLOGY

PFOS and PCB 153 have direct adverse effects on neonatal testis modeled using a coculture of primary gonocyte and sertoli cells

(2011) Jie Zhang et al.   ENVIRONMENTAL TOXICOLOGY

Recent adverse trends in semen quality and testis cancer incidence among Finnish men

(2011) N. Jørgensen et al.   INTERNATIONAL JOURNAL OF ANDROLOGY

Exposure and effective dose biomarkers for perfluorooctane sulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) in infertile subjects: Preliminary results of the PREVIENI project

(2011) Cinzia La Rocca et al.   INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH

Drug transporters and blood–testis barrier function

(2011) Linlin Su et al.   JOURNAL OF ENDOCRINOLOGY

Regional differences and temporal trends in male reproductive health disorders: Semen quality may be a sensitive marker of environmental exposures

(2011) Loa Nordkap et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

P-glycoprotein regulates blood-testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK)

(2011) L. Su et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impacts of environmental toxicants on male reproductive dysfunction

(2011) Elissa W.P. Wong et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

NTP-CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A

(2010) Robert E. Chapin et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Characterization and Functionality of Proliferative Human Sertoli Cells

(2010) Kitty Chui et al.   CELL TRANSPLANTATION

Restricted Arp3 expression in the testis prevents blood-testis barrier disruption during junction restructuring at spermatogenesis

(2010) P. P. Y. Lie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Connexin 43 is critical to maintain the homeostasis of the blood-testis barrier via its effects on tight junction reassembly

(2010) M. W. M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging role for drug transporters at the blood–testis barrier

(2010) Dolores D. Mruk et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Bisphenol A Experience: A Primer for the Analysis of Environmental Effects on Mammalian Reproduction1

(2009) Patricia A. Hunt et al.   BIOLOGY OF REPRODUCTION

Proliferative Activity In Vitro and DNA Repair Indicate that Adult Mouse and Human Sertoli Cells Are Not Terminally Differentiated, Quiescent Cells1

(2009) Emad A. Ahmed et al.   BIOLOGY OF REPRODUCTION

Bisphenol-A and the Great Divide: A Review of Controversies in the Field of Endocrine Disruption

(2009) Laura N. Vandenberg et al.   ENDOCRINE REVIEWS

An Occludin-Focal Adhesion Kinase Protein Complex at the Blood-Testis Barrier: A Study Using the Cadmium Model

(2009) Erica R. Siu et al.   ENDOCRINOLOGY

Do Perfluoroalkyl Compounds Impair Human Semen Quality?

(2009) Ulla Nordström Joensen et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood-testis barrier integrity in the seminiferous epithelium

(2009) Pearl P. Y. Lie et al.   FASEB JOURNAL

Disruption of the blood-testis barrier integrity by bisphenol A in vitro: Is this a suitable model for studying blood-testis barrier dynamics?

(2009) Michelle W.M. Li et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Changes in MAPK pathway in neonatal and adult testis following fetal estrogen exposure and effects on rat testicular cells

(2009) Raphael Thuillier et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Focal adhesion kinase is a blood-testis barrier regulator

(2009) E. R. Siu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Connexin 43 and plakophilin-2 as a protein complex that regulates blood-testis barrier dynamics

(2009) M. W. M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neonatal exposure of male rats to Bisphenol A impairs fertility and expression of sertoli cell junctional proteins in the testis

(2009) Smita Salian et al.   TOXICOLOGY

Cadmium-induced testicular injury

(2009) Erica R. Siu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis

(2008) E. W. P. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cadmium: Toxic effects on the reproductive system and the embryo

(2008) J THOMPSON et al.   REPRODUCTIVE TOXICOLOGY

Cadmium-induced Activation of Stress Signaling Pathways, Disruption of Ubiquitin-dependent Protein Degradation and Apoptosis in Primary Rat Sertoli Cell-Gonocyte Cocultures

(2008) Xiaozhong Yu et al.   TOXICOLOGICAL SCIENCES