Differential Susceptibility of Germ and Leydig Cells to Cadmium-Mediated Toxicity: Impact on Testis Structure, Adiponectin Levels, and Steroidogenesis

Effects of individual and combined toxicity of bisphenol A, dibutyl phthalate and cadmium on oxidative stress and genotoxicity in HepG 2 cells

(2017) Xiaohui Li et al.   FOOD AND CHEMICAL TOXICOLOGY

Cadmium-induced testicular damage is associated with mineral imbalance, increased antioxidant enzymes activity and protein oxidation in rats

(2017) Marli do Carmo Cupertino et al.   LIFE SCIENCES

17β-Estradiol alters oxidative damage and oxidative stress response protein expression in the mouse mammary gland

(2016) Lisi Yuan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Is toxicant-induced Sertoli cell injury in vitro a useful model to study molecular mechanisms in spermatogenesis?

(2016) Nan Li et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Toxic effects of cadmium on testis of birds and mammals: A review

(2015) E. Marettová et al.   ANIMAL REPRODUCTION SCIENCE

Oxidative stress and spermatogenesis suppression in the testis of cadmium-treated Bombyx mori larvae

(2015) Hongxia Yuan et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Sertoli cells are the target of environmental toxicants in the testis – a mechanistic and therapeutic insight

(2015) Ying Gao et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Oxidative stress, bioelements and androgen status in testes of rats subacutely exposed to cadmium

(2015) Ana Djuric et al.   FOOD AND CHEMICAL TOXICOLOGY

Grape juice concentrate (G8000®) intake mitigates testicular morphological and ultrastructural damage following cadmium intoxication

(2015) Celina A. Lamas et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Endocrine disruptive effects of cadmium on steroidogenesis: Human adrenocortical carcinoma cell line NCI-H295R as a cellular model for reproductive toxicity testing

(2015) Zuzana Knazicka et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING

Modulation of oxidative and inflammatory cardiac response by nonselective 1- and 2-cyclooxygenase inhibitor and benznidazole in mice

(2015) Eliziária C. Santos et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The tubular compartment and the spermatogenic dynamics of the wild rodent Oxymycterus nasutus (Rodentia: Cricetidae)

(2014) Ana Carolina Torre Morais et al.   ANIMAL REPRODUCTION SCIENCE

Testing the Genotoxicity, Cytotoxicity, and Oxidative Stress of Cadmium and Nickel and Their Additive Effect in Male Mice

(2014) Ola H. El-Habit et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins

(2014) X. Xiao et al.   HUMAN REPRODUCTION

Elemental Mapping of Cardiac Tissue by Scanning Electron Microscopy and Energy Dispersive X-ray Spectroscopy: Proof of Principle in Chaga's Disease Myocarditis Model

(2013) Rômulo D. Novaes et al.   CANADIAN JOURNAL OF CARDIOLOGY

The flavonoid chrysin attenuates colorectal pathological remodeling reducing the number and severity of pre-neoplastic lesions in rats exposed to the carcinogen 1,2-dimethylhydrazine

(2013) Priscila L. Sequetto et al.   CELL AND TISSUE RESEARCH

Targeting testis-specific proteins to inhibit spermatogenesis: lesson from endocrine disrupting chemicals

(2013) HT Wan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Adiponectin protects Leydig cells against proinflammatory cytokines by suppressing the nuclear factor-κB signaling pathway

(2013) Ling Wu et al.   FEBS Journal

Naringin accelerates the regression of pre-neoplastic lesions and the colorectal structural reorganization in a murine model of chemical carcinogenesis

(2013) Priscila L. Sequetto et al.   FOOD AND CHEMICAL TOXICOLOGY

N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes

(2013) Tingting Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Long-lasting morphofunctional remodelling of liver parenchyma and stroma after a single exposure to low and moderate doses of cadmium in rats

(2013) Marli C. Cupertino et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Endocrine Disruptors Differentially Target ATP-Binding Cassette Transporters in the Blood-Testis Barrier and Affect Leydig Cell Testosterone Secretion In Vitro

(2013) Anita C. A. Dankers et al.   TOXICOLOGICAL SCIENCES

The apical ES–BTB–BM functional axis is an emerging target for toxicant-induced infertility

(2013) Hin-Ting Wan et al.   TRENDS IN MOLECULAR MEDICINE

Uso de fluorescência em um método de dissector modificado para estimar o número de miócitos no tecido cardíaco

(2012) Rômulo Dias Novaes et al.   Arquivos Brasileiros de Cardiologia

Adiponectin expression in patients with inflammatory cardiomyopathy indicates favourable outcome and inflammation control

(2011) Peter Bobbert et al.   EUROPEAN HEART JOURNAL

Effects of Trypanosoma cruzi infection on myocardial morphology, single cardiomyocyte contractile function and exercise tolerance in rats

(2011) Rômulo D. Novaes et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Dihydrolipoamide dehydrogenase and cAMP are associated with cadmium-mediated Leydig cell damage

(2011) Qihao Zhang et al.   TOXICOLOGY LETTERS

Regulation of adiponectin secretion by soy isoflavones has implication for endocrine function of the testis

(2011) Andrew Pfaehler et al.   TOXICOLOGY LETTERS

Impacts of environmental toxicants on male reproductive dysfunction

(2011) Elissa W.P. Wong et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Changes in the Peritubular Tissue of Rat Testis after Cadmium Treatment

(2009) Elena Marettová et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Testis response to low doses of cadmium in Wistar rats

(2009) Fabricia de Souza Predes et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Cadmium-induced apoptosis is mediated by the translocation of AIF to the nucleus in rat testes

(2009) Jisun Kim et al.   TOXICOLOGY LETTERS

Novel Expression and Direct Effects of Adiponectin in the Rat Testis

(2008) J. E. Caminos et al.   ENDOCRINOLOGY

Leydig cell aging and the mechanisms of reduced testosterone synthesis

(2008) Andrew S. Midzak et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Adiponectin and its receptors are expressed in the chicken testis: influence of sexual maturation on testicular ADIPOR1 and ADIPOR2 mRNA abundance

(2008) Olga M Ocón-Grove et al.   REPRODUCTION

Cadmium: Toxic effects on the reproductive system and the embryo

(2008) J THOMPSON et al.   REPRODUCTIVE TOXICOLOGY