Trigonelline, An Alkaloid From Leonurus japonicus Houtt., Suppresses Mast Cell Activation and OVA-Induced Allergic Asthma

Trigonelline protects hippocampal neurons from oxygen-glucose deprivation-induced injury through activating the PI3K/Akt pathway

(2020) Zhengguo Qiu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Anti-inflammatory labdane diterpenoids from Leonurus japonicus Houtt

(2020) Biao Yang et al.   PHYTOCHEMISTRY

AGK2 ameliorates mast cell-mediated allergic airway inflammation and fibrosis by inhibiting FcεRI/TGF-β signaling pathway

(2020) Yeon-Yong Kim et al.   PHARMACOLOGICAL RESEARCH

Inflammatory responses bridge comorbid cardiac disorder in experimental model of IBD induced by DSS: protective effect of the trigonelline

(2019) Hossein Omidi-Ardali et al.   INFLAMMOPHARMACOLOGY

Motherwort Injection for Preventing Postpartum Hemorrhage in Women with Vaginal Delivery: A Systematic Review and Meta-Analysis of Randomized Evidence

(2019) Jiajie Yu et al.   Evidence-based Complementary and Alternative Medicine

Mast Cells and Their Progenitors in Allergic Asthma

(2019) Erika Méndez-Enríquez et al.   Frontiers in Immunology

Therapeutic Potential of Hematopoietic Prostaglandin D2 Synthase in Allergic Inflammation

(2019) Sonja Rittchen et al.   Cells

Leonurus japonicus (Chinese motherwort), an excellent traditional medicine for obstetrical and gynecological diseases: A comprehensive overview

(2019) Lu-Lin Miao et al.   BIOMEDICINE & PHARMACOTHERAPY

Resolution of allergic asthma

(2019) Susetta Finotto   Seminars in Immunopathology

Trigonelline: An alkaloid with anti-degranulation properties

(2019) Arita Dewi Nugrahini et al.   MOLECULAR IMMUNOLOGY

Resveratrol inhibits IL-33–mediated mast cell activation by targeting the MK2/3–PI3K/Akt axis

(2019) Shotaro Nakajima et al.   Scientific Reports

Comparison of asthma phenotypes in OVA-induced mice challenged via inhaled and intranasal routes

(2019) Dong Im Kim et al.   BMC Pulmonary Medicine

Performance of plasma trigonelline as a marker of coffee consumption in an epidemiologic setting

(2018) Øivind Midttun et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

S1P4 Regulates Passive Systemic Anaphylaxis in Mice but Is Dispensable for Canonical IgE-Mediated Responses in Mast Cells

(2018) Joseph Kulinski et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Trigonelline inhibits intestinal microbial metabolism of choline and its associated cardiovascular risk

(2018) Siraj Anwar et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Propofol attenuates mast cell degranulation via inhibiting the miR‑221/PI3K/Akt/Ca2+ pathway

(2018) Zhiyong Yi et al.   Experimental and Therapeutic Medicine

Lobeglitazone Attenuates Airway Inflammation and Mucus Hypersecretion in a Murine Model of Ovalbumin-Induced Asthma

(2018) Na-Rae Shin et al.   Frontiers in Pharmacology

Comparative Analysis of Bone Marrow-derived Mast Cell Differentiation in C57BL/6 and BALB/c Mice

(2018) Miki Nagashima et al.   IMMUNOLOGICAL INVESTIGATIONS

Di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT), an anticancer agent, exerts an anti-inflammatory effect in activated human mast cells

(2017) Sun-Young Nam et al.   INFLAMMATION RESEARCH

Coordination of metabolic pathways: Enhanced carbon conservation in 1,3-propanediol production by coupling with optically pure lactate biosynthesis

(2017) Bo Xin et al.   METABOLIC ENGINEERING

The natural compound nujiangexanthone A suppresses mast cell activation and allergic asthma

(2016) Yue Lu et al.   BIOCHEMICAL PHARMACOLOGY

Lactic Acid Suppresses IL-33–Mediated Mast Cell Inflammatory Responses via Hypoxia-Inducible Factor-1α–Dependent miR-155 Suppression

(2016) Daniel Abebayehu et al.   JOURNAL OF IMMUNOLOGY

Copper oxide nanoparticles aggravate airway inflammation and mucus production in asthmatic mice via MAPK signaling

(2015) Ji-Won Park et al.   Nanotoxicology

PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia

(2015) Tatsuro Nakamura et al.   Nature Communications

Asthma: definitions and pathophysiology

(2015) James W. Mims   International Forum of Allergy & Rhinology

Emodin Isolated from Polygoni cuspidati Radix Inhibits TNF-α and IL-6 Release by Blockading NF-κB and MAP Kinase Pathways in Mast Cells Stimulated with PMA Plus A23187

(2014) Yue Lu et al.   Biomolecules & Therapeutics

Leonurus japonicus Houtt.: Ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine

(2014) Xiaofei Shang et al.   JOURNAL OF ETHNOPHARMACOLOGY

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

(2014) Kana Ogawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mast Cell Mediators: Their Differential Release and the Secretory Pathways Involved

(2014) Tae Chul Moon et al.   Frontiers in Immunology

Inhibition of Protein Kinase C Delta Attenuates Allergic Airway Inflammation through Suppression of PI3K/Akt/mTOR/HIF-1 Alpha/VEGF Pathway

(2013) Yun Ho Choi et al.   PLoS One

Mast Cells and IgE: From History to Today

(2013) Hirohisa Saito et al.   ALLERGOLOGY INTERNATIONAL

Antiallergic effect of Trigonella foenum-graecum L. extracts on allergic skin inflammation induced by trimellitic anhydride in BALB/c mice

(2012) Min-Jung Bae et al.   JOURNAL OF ETHNOPHARMACOLOGY

PGD Synthase and PGD2in Immune Resposne

(2012) Myungsoo Joo et al.   MEDIATORS OF INFLAMMATION

IgE and mast cells in allergic disease

(2012) Stephen J Galli et al.   NATURE MEDICINE

Hypoxia Inducible Factor promotes murine allergic airway inflammation and is increased in asthma and rhinitis

(2011) S. Huerta-Yepez et al.   ALLERGY

MAPKs and NF-κB differentially regulate cytokine expression in the diaphragm in response to resistive breathing: the role of oxidative stress

(2011) Ioanna Sigala et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Inflammation meets cancer, with NF-κB as the matchmaker

(2011) Yinon Ben-Neriah et al.   NATURE IMMUNOLOGY

IgG-mediated systemic anaphylaxis to protein antigen can be induced even under conditions of limited amounts of antibody and antigen

(2010) Ryosuke Ishikawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anti-inflammatory activity of Motherwort (Leonurus sibiricusL.)

(2009) Hye-Young Shin et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

P2 receptor-mediated signaling in mast cell biology

(2009) Elena Bulanova et al.   Purinergic Signalling