Mast Cell Mediators: Their Differential Release and the Secretory Pathways Involved

Mast cells, basophils and B cell connection network

(2015) Sonia Merluzzi et al.   MOLECULAR IMMUNOLOGY

The stealthy nano-machine behind mast cell granule size distribution

(2015) Ilan Hammel et al.   MOLECULAR IMMUNOLOGY

Role of MARCKS in regulated secretion from mast cells and airway goblet cells

(2014) Brookelyn J. Haddock et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Orai-2 is localized on secretory granules and regulates antigen-evoked Ca2+ mobilization and exocytosis in mast cells

(2014) Miho Ikeya et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lipid droplet biogenesis

(2014) Florian Wilfling et al.   CURRENT OPINION IN CELL BIOLOGY

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

A G protein–coupled receptor and the intracellular synthase of its agonist functionally cooperate

(2014) Chantal Binda et al.   JOURNAL OF CELL BIOLOGY

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

(2014) Kana Ogawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Secretogranin III Directs Secretory Vesicle Biogenesis in Mast Cells in a Manner Dependent upon Interaction with Chromogranin A

(2014) P. Prasad et al.   JOURNAL OF IMMUNOLOGY

Rab5 Is a Novel Regulator of Mast Cell Secretory Granules: Impact on Size, Cargo, and Exocytosis

(2014) N. P. Azouz et al.   JOURNAL OF IMMUNOLOGY

Stem cell factor induces AP-1-dependent mast cell IL-6 production via MAPK kinase 3 activity

(2014) Adam J. MacNeil et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Rac1 and Rac2 control distinct events during antigen-stimulated mast cell exocytosis

(2014) Alicia Baier et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Galectin-9 Enhances Cytokine Secretion, but Suppresses Survival and Degranulation, in Human Mast Cell Line

(2014) Reiji Kojima et al.   PLoS One

Nuclear Receptor 4a3 (Nr4a3) Regulates Murine Mast Cell Responses and Granule Content

(2014) Gianni Garcia-Faroldi et al.   PLoS One

Expression of DP2 (CRTh2), a Prostaglandin D2 Receptor, in Human Mast Cells

(2014) Tae Chul Moon et al.   PLoS One

Sorting it out: Regulation of exosome loading

(2014) Carolina Villarroya-Beltri et al.   SEMINARS IN CANCER BIOLOGY

AP-1A Controls Secretory Granule Biogenesis and Trafficking of Membrane Secretory Granule Proteins

(2014) Mathilde Bonnemaison et al.   TRAFFIC

Inhibitory effects of a cationic liposome on allergic reaction mediated by mast cell activation

(2013) Yoshikazu Inoh et al.   BIOCHEMICAL PHARMACOLOGY

Cyclical mechanical stretch enhances degranulation and IL-4 secretion in RBL-2H3 mast cells

(2013) Hidenori Komiyama et al.   CELL BIOCHEMISTRY AND FUNCTION

The STIM1/Orai signaling machinery

(2013) Marc Fahrner et al.   Channels

Mast cells: from lipid droplets to lipid mediators

(2013) Andrea Dichlberger et al.   CLINICAL SCIENCE

Intracellular trafficking and secretion of inflammatory cytokines

(2013) Jennifer L. Stow et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Prevention of F-actin assembly switches the response to SCF from chemotaxis to degranulation in human mast cells

(2013) Daniel Smrž et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Histamine synthesis is required for granule maturation in murine mast cells

(2013) Shunsuke Nakazawa et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human mast cell line-1 (HMC-1) cells exhibit a membrane capacitance increase when dialysed with high free-Ca2+ and GTPγS containing intracellular solution

(2013) Andrea Balletta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of Calcium Ionophore A23187-Induced Activation of IkappaB Kinase 2 in Mast Cells

(2013) Junichi Hosokawa et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Mechanisms of Granule Membrane Recapture following Exocytosis in Intact Mast Cells

(2013) Jose M. Cabeza et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Defensins Activate Human Mast Cells via Mas-Related Gene X2

(2013) H. Subramanian et al.   JOURNAL OF IMMUNOLOGY

Vagal Afferents Mediate Antinociception of Estrogen in a Rat Model of Visceral Pain: The Involvement of Intestinal Mucosal Mast Cells and 5-Hydroxytryptamine 3 Signaling

(2013) Xiu-Juan Yan et al.   JOURNAL OF PAIN

Pleurocidin, a novel antimicrobial peptide, induces human mast cell activation through the FPRL1 receptor

(2013) P Pundir et al.   Mucosal Immunology

The biophysics and cell biology of lipid droplets

(2013) Abdou Rachid Thiam et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of Adaptor Proteins in Secretory Granule Biogenesis and Maturation

(2013) Mathilde L. Bonnemaison et al.   Frontiers in Endocrinology

Vesicular Ca2+ mediates granule motion and exocytosis

(2012) Ricardo Borges et al.   CELL CALCIUM

Ion channels regulating mast cell biology

(2012) I. Ashmole et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Acrolein induction of oxidative stress and degranulation in mast cells

(2012) Daniel J. Hochman et al.   ENVIRONMENTAL TOXICOLOGY

Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion

(2012) Rajesh K. Singh et al.   FEBS Journal

Oxidative Activity of Ammonium Persulfate Salt on Mast Cells and Basophils: Implication in Hairdressers’ Asthma

(2012) Patrizia Pignatti et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Mast Cell Proteoglycans

(2012) Elin Rönnberg et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Microenvironmental regulation of inducible nitric oxide synthase expression and nitric oxide production in mouse bone marrow-derived mast cells

(2012) T. C. Moon et al.   JOURNAL OF LEUKOCYTE BIOLOGY

PGD Synthase and PGD2in Immune Resposne

(2012) Myungsoo Joo et al.   MEDIATORS OF INFLAMMATION

IgE and mast cells in allergic disease

(2012) Stephen J Galli et al.   NATURE MEDICINE

Susceptibility of Young and Adult Rats to the Oral Toxicity of Titanium Dioxide Nanoparticles

(2012) Yun Wang et al.   Small

Mast cell synapses and exosomes: membrane contacts for information exchange

(2012) Amanda Carroll-Portillo   Frontiers in Immunology

The SNARE Machinery in Mast Cell Secretion

(2012) Axel Lorentz et al.   Frontiers in Immunology

The munc13-4-rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane

(2011) E. D. Elstak et al.   BLOOD

Cytokine release from innate immune cells: association with diverse membrane trafficking pathways

(2011) P. Lacy et al.   BLOOD

Single-cell dynamics of mast cell-CD4+CD25+regulatory T cell interactions

(2011) Barbara Frossi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Crucial role for autophagy in degranulation of mast cells

(2011) Hiroko Ushio et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

SNARE complex-mediated degranulation in mast cells

(2011) Joseph R. Woska et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Radiation-induced mast cell mediators differentially modulate chemokine release from dermal fibroblasts

(2011) Kerstin Müller et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

SNAP-23 and syntaxin-3 are required for chemokine release by mature human mast cells

(2011) Simon P.C. Frank et al.   MOLECULAR IMMUNOLOGY

Lipid body function in eicosanoid synthesis: An update

(2011) Patricia T. Bozza et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

The Enlarged Lysosomes in beigej Cells Result From Decreased Lysosome Fission and Not Increased Lysosome Fusion

(2011) Nina Durchfort et al.   TRAFFIC

Cell Secretion Mediated by Granule-Associated Vesicle Transport: A Glimpse at Evolution

(2010) Enrico Crivellato et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Chronological assessment of mast cell-mediated gut dysfunction and mucosal inflammation in a rat model of chronic psychosocial stress

(2010) María Vicario et al.   BRAIN BEHAVIOR AND IMMUNITY

Advanced glycation end products (AGEs) activate mast cells

(2010) E Sick et al.   BRITISH JOURNAL OF PHARMACOLOGY

A Role for Serglycin Proteoglycan in Mast Cell Apoptosis Induced by a Secretory Granule-mediated Pathway

(2010) Fabio Rabelo Melo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silver nanoparticle-induced degranulation observed with quantitative phase microscopy

(2010) Wenzhong Yang et al.   JOURNAL OF BIOMEDICAL OPTICS

Regulation of secretory granule size by the precise generation and fusion of unit granules

(2010) Ilan Hammel et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Antimicrobial Peptides Human  -Defensins and Cathelicidin LL-37 Induce the Secretion of a Pruritogenic Cytokine IL-31 by Human Mast Cells

(2010) F. Niyonsaba et al.   JOURNAL OF IMMUNOLOGY

Quantal basis of vesicle growth and information content, a unified approach

(2010) Eyal Nitzany et al.   JOURNAL OF THEORETICAL BIOLOGY

Age-Related Changes in Proliferation, the Numbers of Mast Cells, Eosinophils, and cd45-Positive Cells in Human Dermis

(2010) A. G. Gunin et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane

(2010) Lisa M. Bond et al.   MOLECULAR BIOLOGY OF THE CELL

Polyamines Are Present in Mast Cell Secretory Granules and Are Important for Granule Homeostasis

(2010) Gianni García-Faroldi et al.   PLoS One

Protein trafficking in immune cells

(2009) Anat Benado et al.   IMMUNOBIOLOGY

Synaptotagmin-2 Controls Regulated Exocytosis but Not Other Secretory Responses of Mast Cells

(2009) Ernestina Melicoff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IgE-FcεRI Interactions Determine HIV Coreceptor Usage and Susceptibility to Infection during Ontogeny of Mast Cells

(2009) J. Bruce Sundstrom et al.   JOURNAL OF IMMUNOLOGY

Advances in mast cell biology: new understanding of heterogeneity and function

(2009) T C Moon et al.   Mucosal Immunology

Novel insights into the biological function of mast cell carboxypeptidase A

(2009) Gunnar Pejler et al.   TRENDS IN IMMUNOLOGY

VAMP-8 segregates mast cell-preformed mediator exocytosis from cytokine trafficking pathways

(2008) N. Tiwari et al.   BLOOD

Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells

(2008) Leif E. Sander et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Zymosan treatment of mouse mast cells enhances dectin-1 expression and induces dectin-1-dependent reactive oxygen species (ROS) generation

(2008) Zhan Yang et al.   IMMUNOBIOLOGY

Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan

(2008) Maria Ringvall et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms

(2008) N. Puri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuropeptides activate human mast cell degranulation and chemokine production

(2007) Marianna Kulka et al.   IMMUNOLOGY