A Personalized Glomerulus Chip Engineered from Stem Cell-Derived Epithelium and Vascular Endothelium

Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association

(2021) Salim S. Virani et al.   CIRCULATION

Rationale and design of the Kidney Precision Medicine Project

(2021) Ian H. de Boer et al.   KIDNEY INTERNATIONAL

Harnessing developmental plasticity to pattern kidney organoids

(2021) Rohan Bhattacharya et al.   Cell Stem Cell

Human iPSCs Stretch to Improve Tissue-Engineered Vascular Grafts

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iPSC-Derived Endothelial Cells Affect Vascular Function in a Tissue-Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome

(2020) Leigh Atchison et al.   Stem Cell Reports

Multivariate patterning of human pluripotent cells under perfusion reveals critical roles of induced paracrine factors in kidney organoid development

(2020) Nick R. Glass et al.   Science Advances

Efficient Drug Screening and Nephrotoxicity Assessment on Co-culture Microfluidic Kidney Chip

(2020) Lei Yin et al.   Scientific Reports

Isotopic Nitrogen-15 Labeling of Mice Identified Long-lived Proteins of the Renal Basement Membranes

(2020) Pan Liu et al.   Scientific Reports

Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk

(2020) Sara E. Howden et al.   Cell Stem Cell

A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier

(2019) Astgik Petrosyan et al.   Nature Communications

A nephron model for study of drug-induced acute kidney injury and assessment of drug-induced nephrotoxicity

(2018) Yueyang Qu et al.   BIOMATERIALS

Single-Cell Transcriptomics of a Human Kidney Allograft Biopsy Specimen Defines a Diverse Inflammatory Response

(2018) Haojia Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip

(2018) Samira Musah et al.   Nature Protocols

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease

(2018) Jihwan Park et al.   SCIENCE

The impact on quality of life of dialysis patients with renal insufficiency

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Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics

(2018) Haojia Wu et al.   Cell Stem Cell

Projecting ESRD Incidence and Prevalence in the United States through 2030

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Characterization of glomerular extracellular matrix by proteomic analysis of laser-captured microdissected glomeruli

(2017) Liliane Hobeika et al.   KIDNEY INTERNATIONAL

A disease model of diabetic nephropathy in a glomerulus-on-a-chip microdevice

(2017) Li Wang et al.   LAB ON A CHIP

Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip

(2017) Samira Musah et al.   Nature Biomedical Engineering

A computational modelling framework to quantify the effects of passaging cell lines

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Podocyte injury and its consequences

(2016) Michio Nagata   KIDNEY INTERNATIONAL

1,3-Dinitrobenzene neurotoxicity – Passage effect in immortalized astrocytes

(2016) Laura L. Maurer et al.   NEUROTOXICOLOGY

Development of a Functional Glomerulus at the Organ Level on a Chip to Mimic Hypertensive Nephropathy

(2016) Mengying Zhou et al.   Scientific Reports

Role of C/EBP-α in Adriamycin-induced podocyte injury

(2016) Fang Zhong et al.   Scientific Reports

The effect of cell passage number on osteogenic and adipogenic characteristics of D1 cells

(2015) K. Kwist et al.   CYTOTECHNOLOGY

A Synthetic Niche for Nephron Progenitor Cells

(2015) Aaron C. Brown et al.   DEVELOPMENTAL CELL

A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents

(2015) Ilka Maschmeyer et al.   LAB ON A CHIP

Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells

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Glomerular Cell Cross-Talk Influences Composition and Assembly of Extracellular Matrix

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The glomerular basement membrane as a barrier to albumin

(2013) Jung Hee Suh et al.   Nature Reviews Nephrology

MMP Mediated Degradation of Type IV Collagen Alpha 1 and Alpha 3 Chains Reflects Basement Membrane Remodeling in Experimental and Clinical Fibrosis – Validation of Two Novel Biomarker Assays

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Role of the Podocyte (and Glomerular Endothelium) in Building the GBM

(2012) Dale R. Abrahamson   SEMINARS IN NEPHROLOGY

The productivity crisis in pharmaceutical R&D

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