Isolation, Crystal Structure, and In Silico Aromatase Inhibition Activity of Ergosta-5, 22-dien-3β-ol from the Fungus Gyromitra esculenta

New combination approaches to combat methicillin-resistant Staphylococcus aureus (MRSA)

(2021) Mohamed H. Sharaf et al.   Scientific Reports

In Silico Studies of Some Isoflavonoids as Potential Candidates against COVID-19 Targeting Human ACE2 (hACE2) and Viral Main Protease (Mpro)

(2021) Mohamed S. Alesawy et al.   MOLECULES

Synthesis and Molecular Docking of Some Grossgemin Amino Derivatives as Tubulin Inhibitors Targeting Colchicine Binding Site

(2021) R. I. Jalmakhanbetova et al.   Journal of Chemistry

Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (COVID-19)

(2021) Amr El-Demerdash et al.   Biomolecules

Isolation and In Silico Anti-COVID-19 Main Protease (Mpro) Activities of Flavonoids and a Sesquiterpene Lactone from Artemisia sublessingiana

(2021) Roza I. Jalmakhanbetova et al.   Journal of Chemistry

Traditional ancient Egyptian medicine: A review

(2021) Ahmed M. Metwaly et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Inhibitory effect of ergosterol on bladder carcinogenesis is due to androgen signaling inhibition by brassicasterol, a metabolite of ergosterol

(2020) Yasuharu Yazawa et al.   Journal of Natural Medicines

Thalassosterol, a New Cytotoxic Aromatase Inhibitor Ergosterol Derivative from the Red Sea Seagrass Thalassodendron ciliatum

(2020) Reda F. A. Abdelhameed et al.   Marine Drugs

Discovery of new quinazolin-4(3H)-ones as VEGFR-2 inhibitors: Design, synthesis, and anti-proliferative evaluation

(2020) Ibrahim.H. Eissa et al.   BIOORGANIC CHEMISTRY

Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors

(2020) Abdel-Ghany A. El-Helby et al.   BIOORGANIC CHEMISTRY

Flavonoids from Pulicaria vulgaris and Their Antimicrobial Activity

(2020) A. Sh. Zhanzhaxina et al.   CHEMISTRY OF NATURAL COMPOUNDS

Design, synthesis, and anti-proliferative evaluation of new quinazolin-4(3H)-ones as potential VEGFR-2 inhibitors

(2020) Khaled El-Adl et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Four New Cytotoxic Arborinane-Type Triterpenes from the Endolichenic Fungus Myrothecium inundatum

(2019) Buddha Basnet et al.   PLANTA MEDICA

Black Ginseng and Its Saponins: Preparation, Phytochemistry and Pharmacological Effects

(2019) Ahmed M. Metwaly et al.   MOLECULES

The Chinese herbal formulae (Yitangkang) exerts an antidiabetic effect through the regulation of substance metabolism and energy metabolism in type 2 diabetic rats

(2019) Xueying Han et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cytotoxic Secondary Metabolites from the Endolichenic Fungus Hypoxylon fuscum

(2019) Buddha Bahadur Basnet et al.   PLANTA MEDICA

Chemical Constituents of Stems and Leaves of Tagetespatula L. and Its Fingerprint

(2019) Yu-Meng Wang et al.   MOLECULES

Apoptosis induced by 9,11‑dehydroergosterol peroxide from Ganoderma�Lucidum mycelium in human malignant melanoma cells is Mcl‑1 dependent

(2018) Lin Zheng et al.   Molecular Medicine Reports

Antilung cancer effect of ergosterol and cisplatin-loaded liposomes modified with cyclic arginine-glycine-aspartic acid and octa-arginine peptides

(2018) Meijia Wu et al.   MEDICINE

Ergostane-Type Sterols from King Trumpet Mushroom (Pleurotus eryngii) and Their Inhibitory Effects on Aromatase

(2017) Takashi Kikuchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

New α-Pyrone derivatives from the endophytic fungus Embellisia sp

(2017) Ahmed M. Metwaly et al.   MEDICINAL CHEMISTRY RESEARCH

Ergosterol peroxide inhibits ovarian cancer cell growth through multiple pathways

(2017) Weiwei Tan et al.   OncoTargets and Therapy

Chemical composition and bioactive compounds of garlic (Allium sativum L.) as affected by pre- and post-harvest conditions: A review

(2016) Natália Martins et al.   FOOD CHEMISTRY

Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer

(2015) Ju-Hee Kang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Ergosterol purified from medicinal mushroom Amauroderma rude inhibits cancer growth in vitro and in vivo by up-regulating multiple tumor suppressors

(2015) Xiangmin Li et al.   Oncotarget

Crystal structure refinement withSHELXL

(2015) George M. Sheldrick   Acta Crystallographica Section C-Structural Chemistry

Sterols from Mytilidae Show Anti-Aging and Neuroprotective Effects via Anti-Oxidative Activity

(2014) Yujuan Sun et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

New antimalarial benzopyran derivatives from the endophytic fungus Alternaria phragmospora

(2014) A Metwaly et al.   PLANTA MEDICA

Antileukemic α-pyrone derivatives from the endophytic fungus Alternaria phragmospora

(2014) Ahmed M. Metwaly et al.   TETRAHEDRON LETTERS

Synthesis and biological activity of (24E)- and (24Z)-26-hydroxydesmosterol

(2013) Ratni Saini et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A New Microcrystalline Phytosterol Polymorph Generated Using CO2-Expanded Solvents

(2013) Evelyn Moreno-Calvo et al.   CRYSTAL GROWTH & DESIGN

Nigrosphaerin A a new isochromene derivative from the endophytic fungus Nigrospora sphaerica

(2013) Ahmed M. Metwaly et al.   Phytochemistry Letters

Antimicrobial peptides from marine invertebrates: Challenges and perspectives in marine antimicrobial peptide discovery

(2011) Sigmund V. Sperstad et al.   BIOTECHNOLOGY ADVANCES

QSAR Studies of CYP2D6 Inhibitor Aryloxypropanolamines Using 2D and 3D Descriptors

(2009) Partha Pratim Roy et al.   Chemical Biology & Drug Design

Ergosterol Peroxide and 9,11-Dehydroergosterol Peroxide from Ling Zhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W. Curt.: Fr.) P. Karst. (Aphyllophoromycetideae) Mycelia Inhibit the Growth of Human Breast Adenocarcinoma MCF-7 Cells

(2009) Lin Zheng et al.   INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS

OLEX2: a complete structure solution, refinement and analysis program

(2009) Oleg V. Dolomanov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY