Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors

Title
Design, synthesis, molecular modeling, in vivo studies and anticancer activity evaluation of new phthalazine derivatives as potential DNA intercalators and topoisomerase II inhibitors
Authors
Keywords
Anticancer, Apoptosis, DNA-intercalation, Molecular docking, Phthalazine, Topoisomerase II
Journal
BIOORGANIC CHEMISTRY
Volume 103, Issue -, Pages 104233
Publisher
Elsevier BV
Online
2020-08-26
DOI
10.1016/j.bioorg.2020.104233

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