A Continuous Battle for Host-Derived Glycans Between a Mucus Specialist and a Glycan Generalist in vitro and in vivo

Proximal colon–derived O-glycosylated mucus encapsulates and modulates the microbiota

(2020) Kirk Bergstrom et al.   SCIENCE

Akkermansia muciniphila ameliorates the age-related decline in colonic mucus thickness and attenuates immune activation in accelerated aging Ercc1−/Δ7 mice

(2019) Benthe van der Lugt et al.   Immunity & Ageing

Glycosylation in health and disease

(2019) Colin Reily et al.   Nature Reviews Nephrology

Identification of a Fifth Antibacterial Toxin Produced by a Single Bacteroides fragilis Strain

(2019) Andrew M. Shumaker et al.   JOURNAL OF BACTERIOLOGY

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

(2019) Clara Depommier et al.   NATURE MEDICINE

The Biosynthesis of Lipooligosaccharide from Bacteroides thetaiotaomicron

(2018) Amy N. Jacobson et al.   mBio

Acquisition of MACPF domain-encoding genes is the main contributor to LPS glycan diversity in gut Bacteroides species

(2018) Valentina Laclare McEneany et al.   ISME Journal

O-antigen dependent colicin insensitivity of uropathogenic Escherichia coli

(2018) Connor Sharp et al.   JOURNAL OF BACTERIOLOGY

Intestinal Muc2 mucin O-glycosylation is affected by microbiota and regulated by differential expression of glycosyltranferases

(2017) Liisa Arike et al.   GLYCOBIOLOGY

Protease inhibition as new therapeutic strategy for GI diseases

(2016) Nathalie Vergnolle   GUT

The physicochemical characterisation of pepsin degraded pig gastric mucin

(2016) Atiga Abodinar et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

What Have We Learned from Glycosyltransferase Knockouts in Mice?

(2016) Pamela Stanley   JOURNAL OF MOLECULAR BIOLOGY

The Ecology and Evolution of Microbial Competition

(2016) Melanie Ghoul et al.   TRENDS IN MICROBIOLOGY

Bacteroidales Secreted Antimicrobial Proteins Target Surface Molecules Necessary for Gut Colonization and Mediate Competition In Vivo

(2016) Kevin G. Roelofs et al.   mBio

The ABC transporter YejABEF is required for resistance to antimicrobial peptides and the virulence of Brucella melitensis

(2016) Zhen Wang et al.   Scientific Reports

Akkermansia muciniphila Adheres to Enterocytes and Strengthens the Integrity of the Epithelial Cell Layer

(2015) Justus Reunanen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Mucins: A biologically relevant glycan barrier in mucosal protection

(2015) Anthony P. Corfield   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Akkermansia muciniphilaand improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology

(2015) Maria Carlota Dao et al.   GUT

Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions

(2015) Carmen Schwechheimer et al.   NATURE REVIEWS MICROBIOLOGY

Comparative transcriptomics reveals key differences in the response to milk oligosaccharides of infant gut-associated bifidobacteria

(2015) Daniel Garrido et al.   Scientific Reports

Mucin glycan foraging in the human gut microbiome

(2015) Louise E. Tailford et al.   Frontiers in Genetics

Suppression of B3GNT7 gene expression in colon adenocarcinoma and its potential effect in the metastasis of colon cancer cells

(2014) Chun-Hao Lu et al.   GLYCOBIOLOGY

An antimicrobial protein of the gut symbiontBacteroides fragiliswith a MACPF domain of host immune proteins

(2014) Maria Chatzidaki-Livanis et al.   MOLECULAR MICROBIOLOGY

STRING v10: protein–protein interaction networks, integrated over the tree of life

(2014) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Faecal Microbiota Composition in Adults Is Associated with the FUT2 Gene Determining the Secretor Status

(2014) Pirjo Wacklin et al.   PLoS One

Preferential Packing of Acidic Glycosidases and Proteases into Bacteroides Outer Membrane Vesicles

(2014) W. Elhenawy et al.   mBio

Mucin-type O-glycans and their roles in intestinal homeostasis

(2013) K. S. B. Bergstrom et al.   GLYCOBIOLOGY

Phylogenetic Analysis of Dysbiosis in Ulcerative Colitis During Remission

(2013) Mirjana Rajilić-Stojanović et al.   INFLAMMATORY BOWEL DISEASES

Site-specificO-Glycosylation on the MUC2 Mucin Protein Inhibits Cleavage by thePorphyromonas gingivalisSecreted Cysteine Protease (RgpB)

(2013) Sjoerd van der Post et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic responses ofBacteroides thetaiotaomicronduring growth on glycan mixtures

(2013) Theresa E. Rogers et al.   MOLECULAR MICROBIOLOGY

Human Gut Microbiota Changes Reveal the Progression of Glucose Intolerance

(2013) Xiuying Zhang et al.   PLoS One

Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota

(2013) P. C. Kashyap et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effect of environmental conditions on expression of Bacteroides fragilis and Bacteroides thetaiotaomicron C10 protease genes

(2012) Roibeard F Thornton et al.   BMC MICROBIOLOGY

Multidomain Carbohydrate-binding Proteins Involved inBacteroides thetaiotaomicronStarch Metabolism

(2012) Elizabeth A. Cameron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

The Microbiota of the Gut in Preschool Children With Normal and Excessive Body Weight

(2012) Caroline L.J. Karlsson et al.   Obesity

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Secretor Genotype (FUT2 gene) Is Strongly Associated with the Composition of Bifidobacteria in the Human Intestine

(2011) Pirjo Wacklin et al.   PLoS One

Recognition and Degradation of Plant Cell Wall Polysaccharides by Two Human Gut Symbionts

(2011) Eric C. Martens et al.   PLOS BIOLOGY

Modulation of Mucosal Immune Response, Tolerance, and Proliferation in Mice Colonized by the Mucin-Degrader Akkermansia muciniphila

(2011) Muriel Derrien et al.   Frontiers in Microbiology

Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiontBacteroides thetaiotaomicron

(2010) Qingping Xu et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria

(2010) Chin Wen Png et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Acute appendicitis is characterised by local invasion with Fusobacterium nucleatum/necrophorum

(2009) A. Swidsinski et al.   GUT

Complex Glycan Catabolism by the Human Gut Microbiota: The Bacteroidetes Sus-like Paradigm

(2009) Eric C. Martens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla

(2009) M. A. Mahowald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mucosal Glycan Foraging Enhances Fitness and Transmission of a Saccharolytic Human Gut Bacterial Symbiont

(2008) Eric C. Martens et al.   Cell Host & Microbe

Lipoprotein biogenesis in Gram-positive bacteria: knowing when to hold ‘em, knowing when to fold ‘em

(2008) Matthew I. Hutchings et al.   TRENDS IN MICROBIOLOGY