Single-cell transcriptomic analyses of T cells in chronic HCV-infected patients dominated by DAA-induced interferon signaling changes

Memory-like HCV-specific CD8+ T cells retain a molecular scar after cure of chronic HCV infection

(2021) Nina Hensel et al.   NATURE IMMUNOLOGY

Early type I IFN blockade improves the efficacy of viral vaccines

(2020) Nicole Palacio et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunological recovery in T-cell activation after sustained virologic response among HIV positive and HIV negative chronic Hepatitis C patients

(2019) Benjamin Emmanuel et al.   Hepatology International

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

JunB plays a crucial role in development of regulatory T cells by promoting IL-2 signaling

(2019) Takaharu Katagiri et al.   Mucosal Immunology

Interferon-λ modulates dendritic cells to facilitate T cell immunity during infection with influenza A virus

(2019) Emily A. Hemann et al.   NATURE IMMUNOLOGY

Killer-like receptors and GPR56 progressive expression defines cytokine production of human CD4+ memory T cells

(2019) Kim-Long Truong et al.   Nature Communications

Direct-Acting Antiviral Treatment of HCV Infection Does Not Resolve the Dysfunction of Circulating CD8+ T-Cells in Advanced Liver Disease

(2019) Agatha Vranjkovic et al.   Frontiers in Immunology

Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians

(2019) Kosuke Hashimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease

(2019) Peter A. Szabo et al.   Nature Communications

Follicular T helper cells shape the HCV-specific CD4+ T cell repertoire after virus elimination

(2019) Maike Smits et al.   JOURNAL OF CLINICAL INVESTIGATION

Gut Dysbiosis Associated With Hepatitis C Virus Infection

(2018) Takako Inoue et al.   CLINICAL INFECTIOUS DISEASES

OUP accepted manuscript

(2018)   CLINICAL INFECTIOUS DISEASES

Baseline intrahepatic and peripheral innate immunity are associated with hepatitis C virus clearance during direct-acting antiviral therapy

(2018) Hawwa Alao et al.   HEPATOLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Hijacking of the AP-1 Signaling Pathway during Development of ATL

(2018) Hélène Gazon et al.   Frontiers in Microbiology

Predicting Early Viral Control under Direct-Acting Antiviral Therapy for Chronic Hepatitis C Virus Using Pretreatment Immunological Markers

(2018) James A. Hutchinson et al.   Frontiers in Immunology

Hepatitis C Vaccines, Antibodies, and T Cells

(2018) Naglaa H. Shoukry   Frontiers in Immunology

Clustering trees: a visualisation for evaluating clusterings at multiple resolutions

(2018) Luke Zappia et al.   GigaScience

Revisiting the Paradox of ISG expression as a predictor of HCV treatment response, a decade later

(2018) Lucy Golden-Mason et al.   HEPATOLOGY

Dynamic changes in innate immune responses during direct-acting antiviral therapy for HCV infection

(2018) Jacinta A. Holmes et al.   JOURNAL OF VIRAL HEPATITIS

Defining Memory CD8 T Cell

(2018) Matthew D. Martin et al.   Frontiers in Immunology

Type I Interferon in Chronic Virus Infection and Cancer

(2017) Laura M. Snell et al.   TRENDS IN IMMUNOLOGY

Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment?

(2017) Federica Sallusto et al.   Cold Spring Harbor Perspectives in Biology

TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation

(2017) Dominik Wieland et al.   Nature Communications

Interferon Lambda Genetics and Biology in Regulation of Viral Control

(2017) Emily A. Hemann et al.   Frontiers in Immunology

Rapid reversal of innate immune dysregulation in blood of patients and livers of humanized mice with HCV following DAA therapy

(2017) Matthew A. Burchill et al.   PLoS One

Memory re-differentiation and reduced lymphocyte activation in chronic HCV-infected patients receiving direct-acting antivirals

(2015) M. A. Burchill et al.   JOURNAL OF VIRAL HEPATITIS

Hepatitis C Virus Infection Is Associated With an Increased Risk of Active Tuberculosis Disease

(2015) Ping-Hsun Wu et al.   MEDICINE

Emerging roles of interferon-stimulated genes in the innate immune response to hepatitis C virus infection

(2014) Mun-Teng Wong et al.   Cellular & Molecular Immunology

Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome

(2014) Eric G. Meissner et al.   JOURNAL OF CLINICAL INVESTIGATION

Restoration of HCV-specific CD8+ T cell function by interferon-free therapy

(2014) Bianca Martin et al.   JOURNAL OF HEPATOLOGY

Innate and adaptive immune responses in HCV infections

(2014) Markus H. Heim et al.   JOURNAL OF HEPATOLOGY

Small Molecule Inhibitors Targeting Activator Protein 1 (AP-1)

(2014) Na Ye et al.   JOURNAL OF MEDICINAL CHEMISTRY

The who's who of T-cell differentiation: Human memory T-cell subsets

(2013) Yolanda D. Mahnke et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Emerging concepts in immunity to hepatitis C virus infection

(2013) Hugo R. Rosen   JOURNAL OF CLINICAL INVESTIGATION

The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus–induced microRNAs

(2013) Adelle P McFarland et al.   NATURE IMMUNOLOGY

Regulation of hepatic innate immunity by hepatitis C virus

(2013) Stacy M Horner et al.   NATURE MEDICINE

Timing and Magnitude of Type I Interferon Responses by Distinct Sensors Impact CD8 T Cell Exhaustion and Chronic Viral Infection

(2012) Yaming Wang et al.   Cell Host & Microbe

Interferon-lambda (IFN- ) induces signal transduction and gene expression in human hepatocytes, but not in lymphocytes or monocytes

(2012) H. Dickensheets et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Type 1 Interferons and Antiviral CD8 T-Cell Responses

(2012) Raymond M. Welsh et al.   PLoS Pathogens

Chronic Hepatitis C Infection

(2011) Hugo R. Rosen   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus

(2011) S. M. Horner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MKP-1 Is Necessary for T Cell Activation and Function

(2009) Yongliang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY