DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses

(2020) Michael Letko et al.   Nature Microbiology

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

(2020) Alexandra C. Walls et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

(2020) Waradon Sungnak et al.   NATURE MEDICINE

Vulnerabilities in coronavirus glycan shields despite extensive glycosylation

(2020) Yasunori Watanabe et al.   Nature Communications

Cytokine Storms: Understanding COVID-19

(2020) Nilam Mangalmurti et al.   IMMUNITY

Is innate immunity our best weapon for flattening the curve?

(2020) Leonard Angka et al.   JOURNAL OF CLINICAL INVESTIGATION

Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses

(2020) Fabian Schmidt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics

(2020) Eskild Petersen et al.   LANCET INFECTIOUS DISEASES

C-Type Lectin Receptors in Host Defense Against Bacterial Pathogens

(2020) Malgorzata E. Mnich et al.   Frontiers in Cellular and Infection Microbiology

The human macrophage galactose‐type lectin, MGL, recognizes the outer core of E. coli lipooligosaccharide

(2019) Meriem Maalej Maalej et al.   CHEMBIOCHEM

Envelope Protein Glycosylation Mediates Zika Virus Pathogenesis

(2019) Derek L. Carbaugh et al.   JOURNAL OF VIROLOGY

Structural basis for human coronavirus attachment to sialic acid receptors

(2019) M. Alejandra Tortorici et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Anti-Siglec-1 antibodies block Ebola viral uptake and decrease cytoplasmic viral entry

(2019) Daniel Perez-Zsolt et al.   Nature Microbiology

Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors

(2019) Young-Jun Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

C-Type Lectin Receptors in Antiviral Immunity and Viral Escape

(2018) Marta Bermejo-Jambrina et al.   Frontiers in Immunology

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

(2017) Jesper Pallesen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ebola virus infection kinetics in chimeric mice reveal a key role of T cells as barriers for virus dissemination

(2017) Anja Lüdtke et al.   Scientific Reports

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

Pseudo-Mannosylated DC-SIGN Ligands as Immunomodulants

(2016) Angela Berzi et al.   Scientific Reports

Designing nanomolar antagonists of DC-SIGN-mediated HIV infection: ligand presentation using molecular rods

(2015) Stefania Ordanini et al.   CHEMICAL COMMUNICATIONS

A multivalent inhibitor of the DC-SIGN dependent uptake of HIV-1 and Dengue virus

(2014) Norbert Varga et al.   BIOMATERIALS

Measles Virus Suppresses RIG-I-like Receptor Activation in Dendritic Cells via DC-SIGN-Mediated Inhibition of PP1 Phosphatases

(2014) Annelies W. Mesman et al.   Cell Host & Microbe

Human Coronavirus NL63 Utilizes Heparan Sulfate Proteoglycans for Attachment to Target Cells

(2014) A. Milewska et al.   JOURNAL OF VIROLOGY

Phenotypic properties of transmitted founder HIV-1

(2013) N. F. Parrish et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of antigen-presenting cells in filoviral hemorrhagic fever: Gaps in current knowledge

(2012) Osvaldo Martinez et al.   ANTIVIRAL RESEARCH

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Glycosaminoglycans Are Interactants of Langerin: Comparison with gp120 Highlights an Unexpected Calcium-Independent Binding Mode

(2012) Eric Chabrol et al.   PLoS One

A Prominent Role for DC-SIGN+ Dendritic Cells in Initiation and Dissemination of Measles Virus Infection in Non-Human Primates

(2012) Annelies W. Mesman et al.   PLoS One

Characterization of Glycosylation Profiles of HIV-1 Transmitted/Founder Envelopes by Mass Spectrometry

(2011) E. P. Go et al.   JOURNAL OF VIROLOGY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Generation of VSV pseudotypes using recombinant ΔG-VSV for studies on virus entry, identification of entry inhibitors, and immune responses to vaccines

(2010) Michael A. Whitt   JOURNAL OF VIROLOGICAL METHODS

C-type lectin Langerin is a β-glucan receptor on human Langerhans cells that recognizes opportunistic and pathogenic fungi

(2010) Marein A.W.P. de Jong et al.   MOLECULAR IMMUNOLOGY

Structural Studies of Langerin and Birbeck Granule: A Macromolecular Organization Model†‡

(2009) Michel Thépaut et al.   BIOCHEMISTRY

DC-SIGN Neck Domain Is a pH-sensor Controlling Oligomerization

(2009) Georges Tabarani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways

(2008) A. A. Lambert et al.   BLOOD

Dendritic cells and C-type lectin receptors: coupling innate to adaptive immune responses

(2008) Sandra J van Vliet et al.   IMMUNOLOGY AND CELL BIOLOGY

Docking, synthesis, and NMR studies of mannosyl trisaccharide ligands for DC-SIGN lectin

(2008) José J. Reina et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Distinct roles for DC-SIGN+-dendritic cells and Langerhans cells in HIV-1 transmission

(2007) Lot de Witte et al.   TRENDS IN MOLECULAR MEDICINE