Machine learning liver-injuring drug interactions with non-steroidal anti-inflammatory drugs (NSAIDs) from a retrospective electronic health record (EHR) cohort

Extended multi‐item gamma Poisson shrinker methods based on the zero‐inflated Poisson model for postmarket drug safety surveillance

(2020) Seok‐Jae Heo et al.   STATISTICS IN MEDICINE

Recent Advances in Hepatotoxicity of Non Steroidal Anti-Inflammatory Drugs

(2018) Lucy Meunier et al.   Annals of Hepatology

Modeling polypharmacy side effects with graph convolutional networks

(2018) Marinka Zitnik et al.   BIOINFORMATICS

The epidemiology of multimorbidity in primary care: a retrospective cohort study

(2018) Anna Cassell et al.   BRITISH JOURNAL OF GENERAL PRACTICE

Deep learning improves prediction of drug–drug and drug–food interactions

(2018) Jae Yong Ryu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CISNE: An accurate description of dose-effect and synergism in combination therapies

(2018) Amador García-Fuente et al.   Scientific Reports

Searching Synergistic Dose Combinations for Anticancer Drugs

(2018) Zuojing Yin et al.   Frontiers in Pharmacology

Columbia Open Health Data, clinical concept prevalence and co-occurrence from electronic health records

(2018) Casey N. Ta et al.   Scientific Data

Topiramate-induced acute liver injury: A rare adverse effect

(2017) Mangala Rao et al.   INDIAN JOURNAL OF PHARMACOLOGY

Combination therapy in combating cancer

(2017) Reza Bayat Mokhtari et al.   Oncotarget

What is polypharmacy? A systematic review of definitions

(2017) Nashwa Masnoon et al.   BMC Geriatrics

Systematic review with network meta-analysis: comparative effectiveness and safety of strategies for preventing NSAID-associated gastrointestinal toxicity

(2016) J. Q. Yuan et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans

(2016) Minjun Chen et al.   DRUG DISCOVERY TODAY

Topiramate-Induced Acute Liver Failure in a Pediatric Patient

(2016) Margaret Z. Tsien et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Changes in Prescription and Over-the-Counter Medication and Dietary Supplement Use Among Older Adults in the United States, 2005 vs 2011

(2016) Dima M. Qato et al.   JAMA Internal Medicine

A survey of current trends in computational drug repositioning

(2015) Jiao Li et al.   BRIEFINGS IN BIOINFORMATICS

Feasibility of Prioritizing Drug–Drug-Event Associations Found in Electronic Health Records

(2015) Juan M. Banda et al.   DRUG SAFETY

Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study

(2015) Naga Chalasani et al.   GASTROENTEROLOGY

Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling

(2015) Santiago Vilar et al.   PLoS One

Systems biology approaches for advancing the discovery of effective drug combinations

(2015) Karen A Ryall et al.   Journal of Cheminformatics

Drug-Induced Liver Injury

(2014) Michael D. Leise et al.   MAYO CLINIC PROCEEDINGS

Performance of Pharmacovigilance Signal-Detection Algorithms for the FDA Adverse Event Reporting System

(2013) R Harpaz et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Mechanisms of Drug-induced Liver Injury

(2013) Liyun Yuan et al.   Clinics in Liver Disease

Multimorbidity in Older Adults

(2013) M. E. Salive   EPIDEMIOLOGIC REVIEWS

Use of Non-Steroidal Anti-Inflammatory Drugs That Elevate Cardiovascular Risk: An Examination of Sales and Essential Medicines Lists in Low-, Middle-, and High-Income Countries

(2013) Patricia McGettigan et al.   PLOS MEDICINE

Data-Driven Prediction of Drug Effects and Interactions

(2012) N. P. Tatonetti et al.   Science Translational Medicine

Chapter 13: Mining Electronic Health Records in the Genomics Era

(2012) Joshua C. Denny   PLoS Computational Biology

Clinical and Histopathologic Features of Fluoroquinolone-Induced Liver Injury

(2011) Eric S. Orman et al.   Clinical Gastroenterology and Hepatology

Assessment of nonsteroidal anti-inflammatory drug-induced hepatotoxicity

(2011) José AG Agúndez et al.   Expert Opinion on Drug Metabolism & Toxicology

Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure

(2010) Niraj Khandelwal et al.   HEPATOLOGY

Deleterious Effects of Reactive Metabolites

(2010) Sabry M. Attia   Oxidative Medicine and Cellular Longevity

Non-steroidal anti-inflammatory drugs: What is the actual risk of liver damage?

(2010) Fernando Bessone   WORLD JOURNAL OF GASTROENTEROLOGY

Synergistic drug combinations tend to improve therapeutically relevant selectivity

(2009) Joseph Lehár et al.   NATURE BIOTECHNOLOGY

In Vitro Evaluation of Reversible and Irreversible Cytochrome P450 Inhibition: Current Status on Methodologies and their Utility for Predicting Drug–Drug Interactions

(2008) Stephen Fowler et al.   AAPS Journal

Causes, Clinical Features, and Outcomes From a Prospective Study of Drug-Induced Liver Injury in the United States

(2008) Naga Chalasani et al.   GASTROENTEROLOGY