N6-methyladenosine promotes induction of ADAR1-mediated A-to-I RNA editing to suppress aberrant antiviral innate immune responses

m6A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2–mediated YAP activity in NSCLC

(2020) Dan Jin et al.   Molecular Cancer

The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression

(2019) Mengru Zhuang et al.   NUCLEIC ACIDS RESEARCH

Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells

(2019) Dali Han et al.   NATURE

Adenosine deaminase acting on RNA (ADAR1), a suppressor of double-stranded RNA–triggered innate immune responses

(2019) Charles E. Samuel   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Gene Expression by N-methyladenosine in Cancer

(2019) Jun Liu et al.   TRENDS IN CELL BIOLOGY

N 6 -Methyladenosines Modulate A-to-I RNA Editing

(2018) Jian-Feng Xiang et al.   MOLECULAR CELL

A-to-I RNA editing — immune protector and transcriptome diversifier

(2018) Eli Eisenberg et al.   NATURE REVIEWS GENETICS

m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer

(2018) Jun Liu et al.   NATURE CELL BIOLOGY

A-to-I RNA editing enzyme ADAR2 regulates light-induced circadian phase-shift

(2018) Hideki Terajima et al.   Scientific Reports

RNA m6 A modification enzymes shape innate responses to DNA by regulating interferon β

(2018) Rosa M. Rubio et al.   GENES & DEVELOPMENT

m6A facilitates hippocampus-dependent learning and memory through YTHDF1

(2018) Hailing Shi et al.   NATURE

m6A modification controls the innate immune response to infection by targeting type I interferons

(2018) Roni Winkler et al.   NATURE IMMUNOLOGY

Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss

(2018) Huayang Liu et al.   NATURE MEDICINE

Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

(2018) Hugh S. Gannon et al.   Nature Communications

The Role of RNA Editing in Cancer Development and Metabolic Disorders

(2018) Che-Pei Kung et al.   Frontiers in Endocrinology

Evolution of transcript modification by N 6 -methyladenosine in primates

(2017) Lijia Ma et al.   GENOME RESEARCH

Detecting RNA modifications in the epitranscriptome: predict and validate

(2017) Mark Helm et al.   NATURE REVIEWS GENETICS

MODOMICS: a database of RNA modification pathways. 2017 update

(2017) Pietro Boccaletto et al.   NUCLEIC ACIDS RESEARCH

RNA editing by ADAR1 leads to context-dependent transcriptome-wide changes in RNA secondary structure

(2017) Oz Solomon et al.   Nature Communications

ADARB1 catalyzes circadian A-to-I editing and regulates RNA rhythm

(2016) Hideki Terajima et al.   NATURE GENETICS

Post-transcriptional gene regulation by mRNA modifications

(2016) Boxuan Simen Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

REDIportal: a comprehensive database of A-to-I RNA editing events in humans

(2016) Ernesto Picardi et al.   NUCLEIC ACIDS RESEARCH

YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

(2016) Hao Du et al.   Nature Communications

5′ UTR m6A Promotes Cap-Independent Translation

(2015) Kate D. Meyer et al.   CELL

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development

(2015) Kathleen Pestal et al.   IMMUNITY

Dynamic m6A mRNA methylation directs translational control of heat shock response

(2015) Jun Zhou et al.   NATURE

StringTie enables improved reconstruction of a transcriptome from RNA-seq reads

(2015) Mihaela Pertea et al.   NATURE BIOTECHNOLOGY

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

A-to-I editing of coding and non-coding RNAs by ADARs

(2015) Kazuko Nishikura   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dynamic control of type I IFN signalling by an integrated network of negative regulators

(2015) Rebecca A. Porritt et al.   TRENDS IN IMMUNOLOGY

N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells

(2014) Yang Wang et al.   NATURE CELL BIOLOGY

REDItools: high-throughput RNA editing detection made easy

(2013) Ernesto Picardi et al.   BIOINFORMATICS

N6-methyladenosine-dependent regulation of messenger RNA stability

(2013) Xiao Wang et al.   NATURE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Global regulation of alternative splicing by adenosine deaminase acting on RNA (ADAR)

(2013) O. Solomon et al.   RNA

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Darned in 2013: inclusion of model organisms and linking with Wikipedia

(2012) Anmol M. Kiran et al.   NUCLEIC ACIDS RESEARCH

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Grand Challenge Commentary: RNA epigenetics?

(2010) Chuan He   Nature Chemical Biology

ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

(2008) Jochen C Hartner et al.   NATURE IMMUNOLOGY