Time-Programmed Delivery of Sorafenib and Anti-CD47 Antibody via a Double-Layer-Gel Matrix for Postsurgical Treatment of Breast Cancer

Trajectory analysis quantifies transcriptional plasticity during macrophage polarization

(2020) Serena X. Liu et al.   Scientific Reports

Current Challenges in Cancer Immunotherapy: Multimodal Approaches to Improve Efficacy and Patient Response Rates

(2019) Manpreet Sambi et al.   Journal of Oncology

Programmable Codelivery of Doxorubicin and Apatinib Using an Implantable Hierarchical-Structured Fiber Device for Overcoming Cancer Multidrug Resistance

(2019) Yang He et al.   Small

Sorafenib Induces Pyroptosis in Macrophages and Triggers Natural Killer Cell–Mediated Cytotoxicity Against Hepatocellular Carcinoma

(2019) Carina Hage et al.   HEPATOLOGY

A Designer Scaffold with Immune Nanoconverters for Reverting Immunosuppression and Enhancing Immune Checkpoint Blockade Therapy

(2019) Hathaichanok Phuengkham et al.   ADVANCED MATERIALS

Tunable Two-Compartment On-Demand Sustained Drug Release Based on Lipid Gels

(2019) Xiuxia Wang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy

(2019) Liping Huang et al.   Nature Communications

A synergistic cancer immunotherapy nano-system for preventing tumor growth

(2019) Yingying Zhang et al.   CHEMICAL ENGINEERING JOURNAL

In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

(2018) Chao Wang et al.   Science Translational Medicine

Degradation-Regulatable Architectured Implantable Macroporous Scaffold for the Spatiotemporal Modulation of Immunosuppressive Microenvironment and Enhanced Combination Cancer Immunotherapy

(2018) Long Ren et al.   ADVANCED FUNCTIONAL MATERIALS

Sandwich-Like Fibers/Sponge Composite Combining Chemotherapy and Hemostasis for Efficient Postoperative Prevention of Tumor Recurrence and Metastasis

(2018) Zhiyun Zhang et al.   ADVANCED MATERIALS

Modulating the Tumor Microenvironment via Oncolytic Viruses and CSF-1R Inhibition Synergistically Enhances Anti-PD-1 Immunotherapy

(2018) Gang Shi et al.   MOLECULAR THERAPY

In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment

(2018) Qian Chen et al.   Nature Nanotechnology

Sorafenib combined with HER-2 targeted vaccination can promote effective T cell immunity in vivo

(2017) Melek M.E. Sunay et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

20-Year Risks of Breast-Cancer Recurrence after Stopping Endocrine Therapy at 5 Years

(2017) Hongchao Pan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeting CD47: the achievements and concerns of current studies on cancer immunotherapy

(2017) Yuting Huang et al.   Journal of Thoracic Disease

Durable antitumor responses to CD47 blockade require adaptive immune stimulation

(2016) Jonathan T. Sockolosky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Molecular Pathways: Activating T Cells after Cancer Cell Phagocytosis from Blockade of CD47 "Don't Eat Me" Signals

(2015) M. N. McCracken et al.   CLINICAL CANCER RESEARCH

Sorafenib inhibits macrophage-induced growth of hepatoma cells by interference with insulin-like growth factor-1 secretion

(2015) Martin Franz Sprinzl et al.   JOURNAL OF HEPATOLOGY

CD47 blockade triggers T cell–mediated destruction of immunogenic tumors

(2015) Xiaojuan Liu et al.   NATURE MEDICINE

A biodegradable thermo-responsive hybrid hydrogel: therapeutic applications in preventing the post-operative recurrence of breast cancer

(2015) Ying Qu et al.   NPG Asia Materials

Immunotherapy: opportunities, risks and future perspectives

(2014) Martin Hildebrandt et al.   CYTOTHERAPY

Synergistic effects of IL-4 and TNFα on the induction of B7-H1 in renal cell carcinoma cells inhibiting allogeneic T cell proliferation

(2014) Dagmar Quandt et al.   Journal of Translational Medicine

Serial Low Doses of Sorafenib Enhance Therapeutic Efficacy of Adoptive T Cell Therapy in a Murine Model by Improving Tumor Microenvironment

(2014) Hui-Yen Chuang et al.   PLoS One

Efficacy of sorafenib as adjuvant therapy to prevent early recurrence of hepatocellular carcinoma after curative surgery: A pilot study

(2013) Shen-Nien Wang et al.   HEPATOLOGY RESEARCH

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

The CD47–SIRPα pathway in cancer immune evasion and potential therapeutic implications

(2012) Mark P Chao et al.   CURRENT OPINION IN IMMUNOLOGY

Notch Signaling Determines the M1 versus M2 Polarization of Macrophages in Antitumor Immune Responses

(2010) Yao-Chun Wang et al.   CANCER RESEARCH

Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma

(2010) Mark P. Chao et al.   CELL

The multikinase inhibitor Sorafenib reverses the suppression of IL-12 and enhancement of IL-10 by PGE2 in murine macrophages

(2010) Justin P. Edwards et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Surgery induced immunosuppression

(2010) Brian V. Hogan et al.   SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND

Radiotherapy plus chemotherapy with or without surgical resection for stage III non-small-cell lung cancer: a phase III randomised controlled trial

(2009) Kathy S Albain et al.   LANCET

The anticancer immune response: indispensable for therapeutic success?

(2008) Laurence Zitvogel et al.   JOURNAL OF CLINICAL INVESTIGATION