Study on the potential active components and molecular mechanism of Xiao Huoluo Pills in the treatment of cartilage degeneration of knee osteoarthritis based on bioinformatics analysis and molecular docking technology

The PI3K/AKT/mTOR signaling pathway in osteoarthritis: a narrative review

(2020) K. Sun et al.   OSTEOARTHRITIS AND CARTILAGE

The protective effect of Ellagic acid (EA) in osteoarthritis: An in vitro and in vivo study

(2020) Zeng Lin et al.   BIOMEDICINE & PHARMACOTHERAPY

Specific manifestations of knee osteoarthritis predict depression and anxiety years in the future: Vancouver Longitudinal Study of Early Knee Osteoarthritis

(2020) Eric C. Sayre et al.   BMC MUSCULOSKELETAL DISORDERS

Mechanobiological model for simulation of injured cartilage degradation via pro-inflammatory cytokines and mechanical stimulus

(2020) Atte S. A. Eskelinen et al.   PLoS Computational Biology

Computational evaluation of altered biomechanics related to articular cartilage lesions observed in vivo

(2019) Katariina A. H. Myller et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Utilising network pharmacology to explore the underlying mechanism of Wumei Pill in treating pancreatic neoplasms

(2019) Yuxiang Wan et al.   BMC Complementary and Alternative Medicine

Nicotine Attenuates Osteoarthritis Pain and Matrix Metalloproteinase-9 Expression via the α7 Nicotinic Acetylcholine Receptor

(2019) Peng Teng et al.   JOURNAL OF IMMUNOLOGY

The Methodological Trends of Traditional Herbal Medicine Employing Network Pharmacology

(2019) Won-Yung Lee et al.   Biomolecules

Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages

(2019) Yue Hu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autodock Vina Adopts More Accurate Binding Poses but Autodock4 Forms Better Binding Affinity

(2019) Nguyen Thanh Nguyen et al.   Journal of Chemical Information and Modeling

Advanced oxidation protein products increase TNF-α and IL-1β expression in chondrocytes via NADPH oxidase 4 and accelerate cartilage degeneration in osteoarthritis progression

(2019) Cong-Rui Liao et al.   Redox Biology

Estimating large covariance matrix with network topology for high-dimensional biomedical data

(2018) Shuo Chen et al.   COMPUTATIONAL STATISTICS & DATA ANALYSIS

Therapeutics in Osteoarthritis Based on an Understanding of Its Molecular Pathogenesis

(2018) Ju-Ryoung Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Bioactive sesquiterpenoids and steroids from the resinous exudates of Commiphora myrrha

(2018) Chi-Yu Ge et al.   NATURAL PRODUCT RESEARCH

Predicting perturbation patterns from the topology of biological networks

(2018) Marc Santolini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional assessment of strains around a full-thickness and critical sized articular cartilage defect under compressive loading using MRI

(2018) L. Zevenbergen et al.   OSTEOARTHRITIS AND CARTILAGE

Pro-inflammatory cytokines: The link between obesity and osteoarthritis

(2018) Tiantian Wang et al.   CYTOKINE & GROWTH FACTOR REVIEWS

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Effects of C-myc gene silencing on interleukin-1β-induced rat chondrocyte cell proliferation, apoptosis and cytokine expression

(2017) Jian Zou et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Cyclin D1 Gene Silencing Promotes IL-1β-Induced Apoptosis in Rat Chondrocytes

(2017) Peng-Fei Zan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Understanding the microscopic binding mechanism of hydroxylated and sulfated polybrominated diphenyl ethers with transthyretin by molecular docking, molecular dynamics simulations and binding free energy calculations

(2017) Huiming Cao et al.   Molecular BioSystems

Purification and function of two analgesic and anti-inflammatory peptides from coelomic fluid of the earthworm, Eisenia foetida

(2017) Chunlong Li et al.   PEPTIDES

Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction

(2016) Jinseol Rhee et al.   ANNALS OF THE RHEUMATIC DISEASES

Targeting VEGF and Its Receptors for the Treatment of Osteoarthritis and Associated Pain

(2016) John L Hamilton et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Prevalence of Symptomatic Knee Osteoarthritis in China: Results From the China Health and Retirement Longitudinal Study

(2016) Xu Tang et al.   Arthritis & Rheumatology

InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams

(2015) Henry Heberle et al.   BMC BIOINFORMATICS

Osteoarthritis

(2015) S Glyn-Jones et al.   LANCET

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

The global burden of hip and knee osteoarthritis: estimates from the Global Burden of Disease 2010 study

(2014) Marita Cross et al.   ANNALS OF THE RHEUMATIC DISEASES

cytoHubba: identifying hub objects and sub-networks from complex interactome

(2014) Chia-Hao Chin et al.   BMC Systems Biology

β-Sitosterol attenuates high-fat diet-induced intestinal inflammation in mice by inhibiting the binding of lipopolysaccharide to toll-like receptor 4 in the NF-κB pathway

(2014) Kyung-Ah Kim et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Endogenous MMP-9 and not MMP-2 promotes rheumatoid synovial fibroblast survival, inflammation and cartilage degradation

(2014) Meilang Xue et al.   RHEUMATOLOGY

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

Activation of Matrix Metalloproteinases 2, 9, and 13 by Activated Protein C in Human Osteoarthritic Cartilage Chondrocytes

(2014) Miriam T. Jackson et al.   Arthritis & Rheumatology

Systems pharmacology in drug discovery and therapeutic insight for herbal medicines

(2013) Chao Huang et al.   BRIEFINGS IN BIOINFORMATICS

Identification of diterpene alkaloids from Aconitum napellus subsp. firmum and GIRK channel activities of some Aconitum alkaloids

(2013) Tivadar Kiss et al.   FITOTERAPIA

A Novel Chemometric Method for the Prediction of Human Oral Bioavailability

(2012) Xue Xu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification and Determination of Aconitum Alkaloids in Aconitum Herbs and Xiaohuoluo Pill Using UPLC-ESI-MS

(2012) Ping Cui et al.   MOLECULES

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee

(2012) Marc C. Hochberg et al.   ARTHRITIS CARE & RESEARCH

BisoGenet: a new tool for gene network building, visualization and analysis

(2010) Alexander Martin et al.   BMC BIOINFORMATICS

Modulation of the immune system by Boswellia serrata extracts and boswellic acids

(2010) H.P.T. Ammon   PHYTOMEDICINE

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Stigmasterol: a phytosterol with potential anti-osteoarthritic properties

(2009) O. Gabay et al.   OSTEOARTHRITIS AND CARTILAGE