ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation
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Title
ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation
Authors
Keywords
A-to-I editing, Aicardi-Goutières syndrome, AGS, Z-DNA, IFIH1, MAVS, short interspersed nuclear element, SINE, type I interferon, autoinflammation
Journal
Cell Reports
Volume 36, Issue 6, Pages 109500
Publisher
Elsevier BV
Online
2021-08-11
DOI
10.1016/j.celrep.2021.109500
References
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