Editing of Cellular Self-RNAs by Adenosine Deaminase ADAR1 Suppresses Innate Immune Stress Responses

Viral RNA detection by RIG-I-like receptors

(2015) Mitsutoshi Yoneyama et al.   CURRENT OPINION IN IMMUNOLOGY

Integration of PKR-dependent translation inhibition with innate immunity is required for a coordinated anti-viral response

(2015) Alexandre Dalet et al.   FEBS LETTERS

Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development

(2015) Kathleen Pestal et al.   IMMUNITY

Measles Virus Defective Interfering RNAs Are Generated Frequently and Early in the Absence of C Protein and Can Be Destabilized by Adenosine Deaminase Acting on RNA-1-Like Hypermutations

(2015) Christian K. Pfaller et al.   JOURNAL OF VIROLOGY

MAVS Coordination of Antiviral Innate Immunity

(2015) Christine Vazquez et al.   JOURNAL OF VIROLOGY

RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself

(2015) B. J. Liddicoat et al.   SCIENCE

STAT2-dependent induction of RNA adenosine deaminase ADAR1 by type I interferon differs between mouse and human cells in the requirement for STAT1

(2015) Cyril X. George et al.   VIROLOGY

Induction of stress granules by interferon and down-regulation by the cellular RNA adenosine deaminase ADAR1

(2014) Lijo John et al.   VIROLOGY

The RNA-Editing Enzyme ADAR1 Controls Innate Immune Responses to RNA

(2014) Niamh M. Mannion et al.   Cell Reports

Mammalian conserved ADAR targets comprise only a small fragment of the human editosome

(2014) Yishay Pinto et al.   GENOME BIOLOGY

A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes

(2013) L. Bazak et al.   GENOME RESEARCH

Measles Virus C Protein Impairs Production of Defective Copyback Double-Stranded Viral RNA and Activation of Protein Kinase R

(2013) C. K. Pfaller et al.   JOURNAL OF VIROLOGY

Quantifying RNA allelic ratios by microfluidic multiplex PCR and sequencing

(2013) Rui Zhang et al.   NATURE METHODS

Identifying RNA editing sites using RNA sequencing data alone

(2013) Gokul Ramaswami et al.   NATURE METHODS

RADAR: a rigorously annotated database of A-to-I RNA editing

(2013) Gokul Ramaswami et al.   NUCLEIC ACIDS RESEARCH

Regulation of stress granules and P-bodies during RNA virus infection

(2013) Richard E. Lloyd   Wiley Interdisciplinary Reviews-RNA

Dynamic Oscillation of Translation and Stress Granule Formation Mark the Cellular Response to Virus Infection

(2012) Alessia Ruggieri et al.   Cell Host & Microbe

Adenosine Deaminase Acting on RNA 1 (ADAR1) Suppresses the Induction of Interferon by Measles Virus

(2012) Z. Li et al.   JOURNAL OF VIROLOGY

Stress Granule Formation Induced by Measles Virus Is Protein Kinase PKR Dependent and Impaired by RNA Adenosine Deaminase ADAR1

(2012) K. M. Okonski et al.   JOURNAL OF VIROLOGY

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

(2012) Gillian I Rice et al.   NATURE GENETICS

Accurate identification of human Alu and non-Alu RNA editing sites

(2012) Gokul Ramaswami et al.   NATURE METHODS

Nucleoside analog studies indicate mechanistic differences between RNA-editing adenosine deaminases

(2012) Rena A. Mizrahi et al.   NUCLEIC ACIDS RESEARCH

High levels of RNA-editing site conservation amongst 15 laboratory mouse strains

(2012) Petr Daneck et al.   GENOME BIOLOGY

Protein kinase PKR and RNA adenosine deaminase ADAR1: new roles for old players as modulators of the interferon response

(2011) Christian K Pfaller et al.   CURRENT OPINION IN IMMUNOLOGY

Host Response to Polyomavirus Infection Is Modulated by RNA Adenosine Deaminase ADAR1 but Not by ADAR2

(2011) C. X. George et al.   JOURNAL OF VIROLOGY

Enhancement of Replication of RNA Viruses by ADAR1 via RNA Editing and Inhibition of RNA-Activated Protein Kinase

(2011) J.-F. Gelinas et al.   JOURNAL OF VIROLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral

(2011) Charles E. Samuel   VIROLOGY

Functions and Regulation of RNA Editing by ADAR Deaminases

(2010) Kazuko Nishikura   Annual Review of Biochemistry

Adenosine Deaminases Acting on RNA, RNA Editing, and Interferon Action

(2010) Cyril X. George et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis

(2010) S. V. Ward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-specific Adenosine Deaminase ADAR1 Suppresses Measles Virus-induced Apoptosis and Activation of Protein Kinase PKR

(2009) Ann M. Toth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Protein Kinase PKR-Mediated Amplification of Beta Interferon Induction by C Protein-Deficient Measles Virus

(2009) C. S. McAllister et al.   JOURNAL OF VIROLOGY

RNA granules: post-transcriptional and epigenetic modulators of gene expression

(2009) Paul Anderson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-Wide Identification of Human RNA Editing Sites by Parallel DNA Capturing and Sequencing

(2009) J. B. Li et al.   SCIENCE

RNA adenosine deaminase ADAR1 deficiency leads to increased activation of protein kinase PKR and reduced vesicular stomatitis virus growth following interferon treatment

(2009) Zhiqun Li et al.   VIROLOGY

P Bodies, Stress Granules, and Viral Life Cycles

(2008) Carla J. Beckham et al.   Cell Host & Microbe

Protein Kinase PKR Mediates the Apoptosis Induction and Growth Restriction Phenotypes of C Protein-Deficient Measles Virus

(2008) A. M. Toth et al.   JOURNAL OF VIROLOGY

ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling

(2008) Jochen C Hartner et al.   NATURE IMMUNOLOGY

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY