An intranasal vaccine durably protects against SARS-CoV-2 variants in mice
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
An intranasal vaccine durably protects against SARS-CoV-2 variants in mice
Authors
Keywords
SARS-CoV-2, COVID-19, vaccine, mucosal immunity, durability, antibody, mice, variants of concern, pathogenesis
Journal
Cell Reports
Volume 36, Issue 4, Pages 109452
Publisher
Elsevier BV
Online
2021-07-10
DOI
10.1016/j.celrep.2021.109452
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- COVID-19 vaccine candidates based on modified vaccinia virus Ankara expressing the SARS-CoV-2 spike induce robust T- and B-cell immune responses and full efficacy in mice
- (2021) Juan García-Arriaza et al. JOURNAL OF VIROLOGY
- Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine
- (2021) Jerald Sadoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection
- (2021) Jennifer M. Dan et al. SCIENCE
- K18-hACE2 mice develop respiratory disease resembling severe COVID-19
- (2021) Claude Kwe Yinda et al. PLoS Pathogens
- Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection
- (2021) Emma S. Winkler et al. CELL
- Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine induced sera
- (2021) Daming Zhou et al. CELL
- Identification of SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization
- (2021) Zhuoming Liu et al. Cell Host & Microbe
- Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7
- (2021) Pengfei Wang et al. NATURE
- mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants
- (2021) Zijun Wang et al. NATURE
- BNT162b vaccines protect rhesus macaques from SARS-CoV-2
- (2021) Annette B. Vogel et al. NATURE
- Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies
- (2021) Rita E. Chen et al. NATURE MEDICINE
- SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma
- (2021) Constantinos Kurt Wibmer et al. NATURE MEDICINE
- Discrete SARS-CoV-2 antibody titers track with functional humoral stability
- (2021) Yannic C. Bartsch et al. Nature Communications
- A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus
- (2021) Bronwyn M. Gunn et al. IMMUNITY
- Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant
- (2021) Shabir A. Madhi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Antibody Persistence through 6 Months after the Second Dose of mRNA-1273 Vaccine for Covid-19
- (2021) Nicole Doria-Rose et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safe and effective two-in-one replicon-and-VLP minispike vaccine for COVID-19: Protection of mice after a single immunization
- (2021) Alexandru A. Hennrich et al. PLoS Pathogens
- Protective Efficacy of Inactivated Vaccine against SARS-CoV-2 Infection in Mice and Non-Human Primates
- (2021) Yan-Feng Yao et al. VIROLOGICA SINICA
- SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern
- (2021) Matthew McCallum et al. SCIENCE
- A single intranasal or intramuscular immunization with chimpanzee adenovirus-vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters
- (2021) Traci L. Bricker et al. Cell Reports
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses
- (2020) Michael Letko et al. Nature Microbiology
- Autopsy Findings and Venous Thromboembolism in Patients With COVID-19
- (2020) Dominic Wichmann et al. ANNALS OF INTERNAL MEDICINE
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Rational Vaccine Design in the Time of COVID-19
- (2020) Dennis R. Burton et al. Cell Host & Microbe
- An Infectious cDNA Clone of SARS-CoV-2
- (2020) Xuping Xie et al. Cell Host & Microbe
- A Mouse Model of SARS-CoV-2 Infection and Pathogenesis
- (2020) Shi-Hui Sun et al. Cell Host & Microbe
- Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
- (2020) Fei Zhou et al. LANCET
- Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
- (2020) Dora Pinto et al. NATURE
- Rapid COVID-19 vaccine development
- (2020) Barney S. Graham SCIENCE
- DNA vaccine protection against SARS-CoV-2 in rhesus macaques
- (2020) Jingyou Yu et al. SCIENCE
- Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis
- (2020) Ren Mao et al. Lancet Gastroenterology & Hepatology
- TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes
- (2020) Ruochen Zang et al. Science Immunology
- Development of an Inactivated Vaccine Candidate, BBIBP-CorV, with Potent Protection against SARS-CoV-2
- (2020) Hui Wang et al. CELL
- Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells
- (2020) Yunlong Cao et al. CELL
- A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies
- (2020) Ahmed O. Hassan et al. CELL
- Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2
- (2020) James Brett Case et al. Cell Host & Microbe
- Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City
- (2020) Eva W. Cheung et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection
- (2020) Wafaa B. Alsoussi et al. JOURNAL OF IMMUNOLOGY
- Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques
- (2020) Noe B. Mercado et al. NATURE
- ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques
- (2020) Neeltje van Doremalen et al. NATURE
- Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein
- (2020) Seth J. Zost et al. NATURE MEDICINE
- Structure-based design of prefusion-stabilized SARS-CoV-2 spikes
- (2020) Ching-Lin Hsieh et al. SCIENCE
- A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2
- (2020) Ahmed O. Hassan et al. CELL
- SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
- (2020) Christopher O. Barnes et al. NATURE
- Animal models for COVID-19
- (2020) César Muñoz-Fontela et al. NATURE
- SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function
- (2020) Emma S. Winkler et al. NATURE IMMUNOLOGY
- Ad26 vaccine protects against SARS-CoV-2 severe clinical disease in hamsters
- (2020) Lisa H. Tostanoski et al. NATURE MEDICINE
- Humoral Immune Response to SARS-CoV-2 in Iceland
- (2020) Daniel F. Gudbjartsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
- (2020) Longxing Cao et al. SCIENCE
- Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
- (2020) M. Alejandra Tortorici et al. SCIENCE
- Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy
- (2020) Alex W. Wessel et al. Nature Communications
- Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease
- (2020) Joseph W. Golden et al. JCI Insight
- Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo
- (2020) Alexandra Schäfer et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses
- (2020) Jordan R. Barrett et al. NATURE MEDICINE
- Durability of Responses after SARS-CoV-2 mRNA-1273 Vaccination
- (2020) Alicia T. Widge et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
- (2020) Lindsey R. Baden et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
- (2020) Fernando P. Polack et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Sample-Sparing Multiplexed ADCP Assay
- (2019) Audrey L. Butler et al. Frontiers in Immunology
- Multiplexed Fc array for evaluation of antigen-specific antibody effector profiles
- (2017) Eric P. Brown et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Mouse and human FcR effector functions
- (2015) Pierre Bruhns et al. IMMUNOLOGICAL REVIEWS
- Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants
- (2011) Whitney E. Purtha et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mechanisms that determine plasma cell lifespan and the duration of humoral immunity
- (2010) Ian J. Amanna et al. IMMUNOLOGICAL REVIEWS
- Creation of a panel of vectors based on ape adenovirus isolates
- (2010) Soumitra Roy et al. JOURNAL OF GENE MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started