Transcriptionally inactive hepatitis B virus episome DNA preferentially resides in the vicinity of chromosome 19 in 3D host genome upon infection

DNA Polymerase alpha is essential for intracellular amplification of hepatitis B virus covalently closed circular DNA

(2019) Liudi Tang et al.   PLoS Pathogens

Spatiotemporal Analysis of Hepatitis B Virus X Protein in Primary Human Hepatocytes

(2019) Dmytro Kornyeyev et al.   JOURNAL OF VIROLOGY

A global scientific strategy to cure hepatitis B

(2019) Peter A Revill et al.   Lancet Gastroenterology & Hepatology

Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus

(2018) Sofia A. Quinodoz et al.   CELL

OligoMiner provides a rapid, flexible environment for the design of genome-scale oligonucleotide in situ hybridization probes

(2018) Brian J. Beliveau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription Elongation Can Affect Genome 3D Structure

(2018) Sven Heinz et al.   CELL

Three-dimensional genome structures of single diploid human cells

(2018) Longzhi Tan et al.   SCIENCE

Tridimensional infiltration of DNA viruses into the host genome shows preferential contact with active chromatin

(2018) Pierrick Moreau et al.   Nature Communications

Proliferation of primary human hepatocytes and prevention of hepatitis B virus reinfection efficiently deplete nuclear cccDNA in vivo

(2017) Lena Allweiss et al.   GUT

Chronic hepatitis B: divide and conquer?

(2017) Michael Nassal   GUT

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(2017) Edward J. Gane   LIVER INTERNATIONAL

Phase separation drives heterochromatin domain formation

(2017) Amy R. Strom et al.   NATURE

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

(2017) Adam G. Larson et al.   NATURE

The condensin complex is a mechanochemical motor that translocates along DNA

(2017) Tsuyoshi Terakawa et al.   SCIENCE

Nuclear Import of Hepatitis B Virus Capsids and Genome

(2017) Lara Gallucci et al.   Viruses-Basel

A potent human neutralizing antibody Fc-dependently reduces established HBV infections

(2017) Dan Li et al.   eLife

The 3D Genome as Moderator of Chromosomal Communication

(2016) Job Dekker et al.   CELL

Nucleolar organizer regions: genomic ‘dark matter’ requiring illumination

(2016) Brian McStay   GENES & DEVELOPMENT

HBV replication, pathobiology and therapy: Unanswered questions

(2016) Christoph Seeger et al.   JOURNAL OF HEPATOLOGY

Chromatin Domains: The Unit of Chromosome Organization

(2016) Jesse R. Dixon et al.   MOLECULAR CELL

Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor

(2016) Adrien Decorsière et al.   NATURE

Super-resolution imaging reveals distinct chromatin folding for different epigenetic states

(2016) Alistair N. Boettiger et al.   NATURE

Organization and function of the 3D genome

(2016) Boyan Bonev et al.   NATURE REVIEWS GENETICS

The molecular hallmarks of epigenetic control

(2016) C. David Allis et al.   NATURE REVIEWS GENETICS

Spatial organization of chromatin domains and compartments in single chromosomes

(2016) Siyuan Wang et al.   SCIENCE

Hepatitis B Virus X Protein Promotes Degradation of SMC5/6 to Enhance HBV Replication

(2016) Christopher M. Murphy et al.   Cell Reports

DNA Polymerase κ Is a Key Cellular Factor for the Formation of Covalently Closed Circular DNA of Hepatitis B Virus

(2016) Yonghe Qi et al.   PLoS Pathogens

Towards an HBV cure: state-of-the-art and unresolved questions—report of the ANRS workshop on HBV cure

(2015) Mirjam B Zeisel et al.   GUT

HBV cccDNA: viral persistence reservoir and key obstacle for a cure of chronic hepatitis B

(2015) Michael Nassal   GUT

Present and future therapies of hepatitis B: From discovery to cure

(2015) T. Jake Liang et al.   HEPATOLOGY

Estimating the global prevalence of hepatitis B

(2015) Jennifer H MacLachlan et al.   LANCET

Estimations of worldwide prevalence of chronic hepatitis B virus infection: a systematic review of data published between 1965 and 2013

(2015) Aparna Schweitzer et al.   LANCET

Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2015)   LANCET

Spatially resolved, highly multiplexed RNA profiling in single cells

(2015) K. H. Chen et al.   SCIENCE

Molecular biology of hepatitis B virus infection

(2015) Christoph Seeger et al.   VIROLOGY

Long-Range Chromatin Interactions

(2015) Job Dekker et al.   Cold Spring Harbor Perspectives in Biology

Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes

(2015) Brian J. Beliveau et al.   Nature Communications

Viruses and the nucleolus: The fatal attraction

(2014) Anna Salvetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B viruses

(2014) Christian Königer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic hepatitis B: What should be the goal for new therapies?

(2013) Timothy M. Block et al.   ANTIVIRAL RESEARCH

Hepatitis B and D Viruses Exploit Sodium Taurocholate Co-transporting Polypeptide for Species-Specific Entry into Hepatocytes

(2013) Yi Ni et al.   GASTROENTEROLOGY

Multiplexed chromosome conformation capture sequencing for rapid genome-scale high-resolution detection of long-range chromatin interactions

(2013) Ralph Stadhouders et al.   Nature Protocols

A decade of 3C technologies: insights into nuclear organization

(2012) E. de Wit et al.   GENES & DEVELOPMENT

Hepatitis B virus X protein stimulates gene expression selectively from extrachromosomal DNA templates

(2012) Pieter C. van Breugel et al.   HEPATOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Spatial partitioning of the regulatory landscape of the X-inactivation centre

(2012) Elphège P. Nora et al.   NATURE

Versatile design and synthesis platform for visualizing genomes with Oligopaint FISH probes

(2012) B. J. Beliveau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus

(2012) Huan Yan et al.   eLife

Two Forms of Loops Generate the Chromatin Conformation of the Immunoglobulin Heavy-Chain Gene Locus

(2011) Changying Guo et al.   CELL

A Regulatory Archipelago Controls Hox Genes Transcription in Digits

(2011) Thomas Montavon et al.   CELL

Hepatitis B virus X protein is essential to initiate and maintain virus replication after infection

(2011) Julie Lucifora et al.   JOURNAL OF HEPATOLOGY

The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules

(2010) Davide Baù et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Hep G2 is a hepatoblastoma-derived cell line

(2009) Dolores López-Terrada et al.   HUMAN PATHOLOGY

The Latent Origin of Replication of Epstein-Barr Virus Directs Viral Genomes to Active Regions of the Nucleus

(2009) M. J. Deutsch et al.   JOURNAL OF VIROLOGY

Design of 240,000 orthogonal 25mer DNA barcode probes

(2009) Q. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE