Tumor Associated Macrophages and TAMs‐Based Anti‐Tumor Nanomedicines

Polarization of Tumor-Associated Macrophages by Nanoparticle-Loaded Escherichia coli Combined with Immunogenic Cell Death for Cancer Immunotherapy

(2021) Baicheng Wei et al.   NANO LETTERS

The Antitumor Efficacy of CpG Oligonucleotides is Improved by Encapsulation in Plant Virus‐Like Particles

(2020) Hui Cai et al.   ADVANCED FUNCTIONAL MATERIALS

Metal–Organic Framework Nanoparticles for Ameliorating Breast Cancer-Associated Osteolysis

(2020) Yichuan Pang et al.   NANO LETTERS

Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses

(2020) Jesse M. Jaynes et al.   Science Translational Medicine

Biologically Responsive Plasmonic Assemblies for Second Near-Infrared Window Photoacoustic Imaging-Guided Concurrent Chemo-Immunotherapy

(2020) Rong Zhu et al.   ACS Nano

Noncovalent Indocyanine Green Conjugate of C-Phycocyanin: Preparation and Tumor-Associated Macrophages-Targeted Photothermal Therapeutics

(2020) Dong-Hua Wan et al.   BIOCONJUGATE CHEMISTRY

Remodeling tumor immune microenvironment via targeted blockade of PI3K-γ and CSF-1/CSF-1R pathways in tumor associated macrophages for pancreatic cancer therapy

(2020) Man Li et al.   JOURNAL OF CONTROLLED RELEASE

Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy

(2020) Stephanie J. Wang et al.   Science Advances

The role of tumor-associated macrophages in gastric cancer development and their potential as a therapeutic target

(2020) V. Gambardella et al.   CANCER TREATMENT REVIEWS

Polarization and function of tumor-associated macrophages mediate graphene oxide-induced photothermal cancer therapy

(2020) Xiangyu Deng et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Metabolic modulation via mTOR pathway and anti-angiogenesis remodels tumor microenvironment using PD-L1-targeting codelivery

(2020) Binfan Chen et al.   BIOMATERIALS

Targeted delivery of chlorogenic acid by mannosylated liposomes to effectively promote the polarization of TAMs for the treatment of glioblastoma

(2020) Jun Ye et al.   Bioactive Materials

Tailoring Nanomaterials for Targeting Tumor‐Associated Macrophages

(2019) Muhammad Ovais et al.   ADVANCED MATERIALS

Phase I Study of Emactuzumab Single Agent or in Combination with Paclitaxel in Patients with Advanced/Metastatic Solid Tumors Reveals Depletion of Immunosuppressive M2-like Macrophages

(2019) C A Gomez-Roca et al.   ANNALS OF ONCOLOGY

Macrophage CCL 22 Expression in the Tumor Microenvironment and Implications for Survival in Patients with Squamous Cell Carcinoma of the Tongue

(2019) Satoshi Kimura et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Nanoparticles from Cuttlefish Ink Inhibit Tumor Growth by Synergizing Immunotherapy and Photothermal Therapy

(2019) Rong-Hui Deng et al.   ACS Nano

Role of therapeutic agents on repolarisation of tumour associated macrophage to halt lung cancer progression

(2019) Hibah M. Aldawsari et al.   JOURNAL OF DRUG TARGETING

CSF1R‐ and SHP2‐Inhibitor‐Loaded Nanoparticles Enhance Cytotoxic Activity and Phagocytosis in Tumor‐Associated Macrophages

(2019) Anujan Ramesh et al.   ADVANCED MATERIALS

Iron chelated melanin-like nanoparticles for tumor-associated macrophage repolarization and cancer therapy

(2019) Lei Rong et al.   BIOMATERIALS

Dual inhibition of CSF1R and MAPK pathways using supramolecular nanoparticles enhances macrophage immunotherapy

(2019) Anujan Ramesh et al.   BIOMATERIALS

Target delivery selective CSF-1R inhibitor to tumor-associated macrophages via erythrocyte-cancer cell hybrid membrane camouflaged pH-responsive copolymer micelle for cancer immunotherapy

(2019) Yuchi Wang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Triple negative breast cancer: Key role of Tumor-Associated Macrophages in regulating the activity of anti-PD-1/PD-L1 agents

(2018) Matteo Santoni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Emergence of synthetic mRNA: In vitro synthesis of mRNA and its applications in regenerative medicine

(2018) Hyokyoung Kwon et al.   BIOMATERIALS

Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b

(2018) Neha N. Parayath et al.   NANO LETTERS

M1 Macrophage-Derived Nanovesicles Potentiate the Anticancer Efficacy of Immune Checkpoint Inhibitors

(2018) Yeon Woong Choo et al.   ACS Nano

Combination antitumor immunotherapy with VEGF and PIGF siRNA via systemic delivery of multi-functionalized nanoparticles to tumor-associated macrophages and breast cancer cells

(2018) Yudong Song et al.   BIOMATERIALS

Calcium Bisphosphonate Nanoparticles with Chelator-Free Radiolabeling to Deplete Tumor-Associated Macrophages for Enhanced Cancer Radioisotope Therapy

(2018) Longlong Tian et al.   ACS Nano

Molecular Repolarisation of Tumour-Associated Macrophages

(2018) Floris van Dalen et al.   MOLECULES

Nanomedicine Strategies to Target Tumor-Associated Macrophages

(2017) Karin Binnemars-Postma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Macropinocytosis of Nab-paclitaxel Drives Macrophage Activation in Pancreatic Cancer

(2017) Jane Cullis et al.   Cancer Immunology Research

Precision Targeting of Tumor Macrophages with a CD206 Binding Peptide

(2017) Pablo Scodeller et al.   Scientific Reports

Utilizing Viral Nanoparticle/Dendron Hybrid Conjugates in Photodynamic Therapy for Dual Delivery to Macrophages and Cancer Cells

(2016) Amy M. Wen et al.   BIOCONJUGATE CHEMISTRY

Tumor Microenvironment-Responsive Nanoparticle Delivery of Chemotherapy for Enhanced Selective Cellular Uptake and Transportation within Tumor

(2016) Wen-Chia Huang et al.   BIOMACROMOLECULES

Immune Cells in Cancer Therapy and Drug Delivery

(2016) Ceren Eyileten et al.   MEDIATORS OF INFLAMMATION

Co-evolution of tumor-associated macrophages and tumor neo-vessels during cervical cancer invasion

(2016) Shuting Jiang et al.   Oncology Letters

Bioconjugated Manganese Dioxide Nanoparticles Enhance Chemotherapy Response by Priming Tumor-Associated Macrophages toward M1-like Phenotype and Attenuating Tumor Hypoxia

(2015) Manli Song et al.   ACS Nano

CXCR4-targeted lipid-coated PLGA nanoparticles deliver sorafenib and overcome acquired drug resistance in liver cancer

(2015) Dong-Yu Gao et al.   BIOMATERIALS

Tumor microenvironment: Sanctuary of the devil

(2015) Lanlan Hui et al.   CANCER LETTERS

T H 2-Polarized CD4 + T Cells and Macrophages Limit Efficacy of Radiotherapy

(2015) Stephen L. Shiao et al.   Cancer Immunology Research

Myeloid WNT7b Mediates the Angiogenic Switch and Metastasis in Breast Cancer

(2014) E.-J. Yeo et al.   CANCER RESEARCH

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Enhancement of DNA Vaccine Potency Against Legumain

(2014) Michal Smahel et al.   JOURNAL OF IMMUNOTHERAPY

Depletion of M2-Like Tumor-Associated Macrophages Delays Cutaneous T-Cell Lymphoma Development In Vivo

(2014) Xuesong Wu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

SPARC Expression Correlates with Tumor Response to Albumin-Bound Paclitaxel in Head and Neck Cancer Patients

(2014) Neil Desai et al.   Translational Oncology

Concise Review: Breast Cancer Stem Cells: Regulatory Networks, Stem Cell Niches, and Disease Relevance

(2014) Wenjun Guo   Stem Cells Translational Medicine

The heterogeneous immune microenvironment in breast cancer is affected by hypoxia-related genes

(2013) Markus Duechler et al.   IMMUNOBIOLOGY

Targeting tumor-infiltrating macrophages to combat cancer

(2013) Roheena Z Panni et al.   Immunotherapy

Real-time phase-contrast imaging of photothermal treatment of head and neck squamous cell carcinoma: anin vitrostudy of macrophages as a vector for the delivery of gold nanoshells

(2013) Taeseok Daniel Yang et al.   JOURNAL OF BIOMEDICAL OPTICS

Specific Transfection of Inflamed Brain by Macrophages: A New Therapeutic Strategy for Neurodegenerative Diseases

(2013) Matthew J. Haney et al.   PLoS One

Hydrazinocurcumin Encapsuled Nanoparticles “Re-Educate” Tumor-Associated Macrophages and Exhibit Anti-Tumor Effects on Breast Cancer Following STAT3 Suppression

(2013) Xiwen Zhang et al.   PLoS One

YKL-40 acts as an angiogenic factor to promote tumor angiogenesis

(2013) Rong Shao   Frontiers in Physiology

PET imaging of tumor associated macrophages using mannose coated 64Cu liposomes

(2012) Landon W. Locke et al.   BIOMATERIALS

CCR2-Dependent Recruitment of Macrophages by Tumor-Educated Mesenchymal Stromal Cells Promotes Tumor Development and Is Mimicked by TNFα

(2012) Guangwen Ren et al.   Cell Stem Cell

Anti-tumour strategies aiming to target tumour-associated macrophages

(2012) Xiaoqiang Tang et al.   IMMUNOLOGY

Efficient intracellular drug-targeting of macrophages using stealth liposomes directed to the hemoglobin scavenger receptor CD163

(2012) Anders Etzerodt et al.   JOURNAL OF CONTROLLED RELEASE

Blood-borne macrophage–neural cell interactions hitchhike on endosome networks for cell-based nanozyme brain delivery

(2012) Matthew J Haney et al.   Nanomedicine

Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor: A Meta-Analysis of the Literature

(2012) Qiong-wen Zhang et al.   PLoS One

Origins of tumor-associated macrophages and neutrophils

(2012) V. Cortez-Retamozo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential macrophage programming in the tumor microenvironment

(2012) Brian Ruffell et al.   TRENDS IN IMMUNOLOGY

Magnetic-Fe/Fe3O4-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages

(2012) Hongwang Wang et al.   Beilstein Journal of Nanotechnology

Macrophages as Cell-Based Delivery Systems for Nanoshells in Photothermal Therapy

(2011) Steen J. Madsen et al.   ANNALS OF BIOMEDICAL ENGINEERING

Liposomes surface conjugated with human hemoglobin target delivery to macrophages

(2011) Ning Zhang et al.   BIOTECHNOLOGY AND BIOENGINEERING

TNF-α renders macrophages resistant to a range of cancer chemotherapeutic agents through NF-κB-mediated antagonism of apoptosis signalling

(2011) Susan Z.Y. Lo et al.   CANCER LETTERS

Hypoxia, tumour-associated macrophages, microvessel density, VEGF and matrix metalloproteinases in human gastric cancer: interaction and impact on survival

(2011) Sergej Osinsky et al.   Clinical & Translational Oncology

Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

(2011) T. Shree et al.   GENES & DEVELOPMENT

Targeted delivery of oligonucleotides into tumor-associated macrophages for cancer immunotherapy

(2011) Zhen Huang et al.   JOURNAL OF CONTROLLED RELEASE

A Critical Role for Macrophages in Promotion of Urethane-Induced Lung Carcinogenesis

(2011) R. Zaynagetdinov et al.   JOURNAL OF IMMUNOLOGY

Identification and manipulation of tumor associated macrophages in human cancers

(2011) Moniek Heusinkveld et al.   Journal of Translational Medicine

Tumour macrophages as potential targets of bisphosphonates

(2011) Thea L Rogers et al.   Journal of Translational Medicine

Bio-inspired, bioengineered and biomimetic drug delivery carriers

(2011) Jin-Wook Yoo et al.   NATURE REVIEWS DRUG DISCOVERY

Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

(2011) M. Jinushi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics

(2010) Rita A Mukhtar et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

A New Era for Cancer Treatment: Gold-Nanoparticle-Mediated Thermal Therapies

(2010) Laura C. Kennedy et al.   Small

Macrophages are an abundant component of myeloma microenvironment and protect myeloma cells from chemotherapy drug-induced apoptosis

(2009) Y. Zheng et al.   BLOOD

Anti-Tumour Effects of Bisphosphonates - What have we Learned from In Vivo Models?

(2009) H. Brown et al.   CURRENT CANCER DRUG TARGETS

Brain-targeted solid lipid nanoparticles containing riluzole: preparation, characterization and biodistribution

(2009) Maria Luisa Bondì et al.   Nanomedicine

The inflammatory micro-environment in tumor progression: The role of tumor-associated macrophages

(2008) Paola Allavena et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY