Localized Chemotherapy Based on Injectable Hydrogel Boosts the Antitumor Activity of Adoptively Transferred T Lymphocytes In Vivo

An injectable hydrogel using an immunomodulating gelator for amplified tumor immunotherapy by blocking the arginase pathway

(2021) Xiaomeng Ren et al.   Acta Biomaterialia

Supramolecular Nanofibrils Formed by Coassembly of Clinically Approved Drugs for Tumor Photothermal Immunotherapy

(2021) Shukun Li et al.   ADVANCED MATERIALS

Injectable Hydrogels as Local Depots at Tumor Sites for Antitumor Immunotherapy and Immune‐Based Combination Therapy

(2021) Hongyu Ma et al.   MACROMOLECULAR BIOSCIENCE

Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses

(2020) Yu Chao et al.   Science Advances

The Promise of Combining Radiation Therapy With Immunotherapy

(2020) Justin C. Jagodinsky et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

The Tumor Microenvironment: A Milieu Hindering and Obstructing Antitumor Immune Responses

(2020) Alireza Labani-Motlagh et al.   Frontiers in Immunology

Supramolecular prodrug hydrogelator as an immune booster for checkpoint blocker–based immunotherapy

(2020) Feihu Wang et al.   Science Advances

Injectable Anti-inflammatory Nanofiber Hydrogel to Achieve Systemic Immunotherapy Post Local Administration

(2020) Muchao Chen et al.   NANO LETTERS

Role of nanoparticle-mediated immunogenic cell death in cancer immunotherapy

(2020) Yajie Sun et al.   Asian Journal of Pharmaceutical Sciences

Multifunctional drug-loaded micelles encapsulated in thermo-sensitive hydrogel for in vivo local cancer treatment: Synergistic effects of anti-vascular and immuno-chemotherapy

(2020) Haile Fentahun Darge et al.   CHEMICAL ENGINEERING JOURNAL

Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells

(2019) Qian Chen et al.   ADVANCED MATERIALS

Nanoengineered Immune Niches for Reprogramming the Immunosuppressive Tumor Microenvironment and Enhancing Cancer Immunotherapy

(2019) Hathaichanok Phuengkham et al.   ADVANCED MATERIALS

Magnetic Nanoclusters Armed with Responsive PD-1 Antibody Synergistically Improved Adoptive T-Cell Therapy for Solid Tumors

(2019) Weidong Nie et al.   ACS Nano

Adoptive T-Cell Therapy for Solid Malignancies

(2019) Mohammad S. Jafferji et al.   Surgical Oncology Clinics of North America

Smart Injectable Hydrogels for Cancer Immunotherapy

(2019) Yu Chao et al.   ADVANCED FUNCTIONAL MATERIALS

Adoptive CD8+ T cell therapy against cancer:Challenges and opportunities

(2019) Xiaotao Jiang et al.   CANCER LETTERS

Tumor Ablation and Therapeutic Immunity Induction by an Injectable Peptide Hydrogel

(2018) Honglin Jin et al.   ACS Nano

Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade

(2018) Shuangjiang Yu et al.   ADVANCED MATERIALS

SYK-targeted dendritic cell-mediated cytotoxic T lymphocytes enhance the effect of immunotherapy on retinoblastoma

(2018) Xuemei Chen et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity

(2018) Eric M. Mastria et al.   JOURNAL OF CONTROLLED RELEASE

In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

(2018) Chao Wang et al.   Science Translational Medicine

Elimination of established tumors with nanodisc-based combination chemoimmunotherapy

(2018) Rui Kuai et al.   Science Advances

A Phase Ib/II Study of Ganetespib With Doxorubicin in Advanced Solid Tumors Including Relapsed-Refractory Small Cell Lung Cancer

(2018) Deepa S. Subramaniam et al.   Frontiers in Oncology

Adoptive cellular therapies: the current landscape

(2018) Maartje W. Rohaan et al.   VIRCHOWS ARCHIV

Interleukin-15 and cisplatin co-encapsulated thermosensitive polypeptide hydrogels for combined immuno-chemotherapy

(2017) Xilong Wu et al.   JOURNAL OF CONTROLLED RELEASE

Co-delivery of chemotherapeutics and proteins for synergistic therapy

(2016) Chaoliang He et al.   ADVANCED DRUG DELIVERY REVIEWS

Low dose gemcitabine-loaded lipid nanocapsules target monocytic myeloid-derived suppressor cells and potentiate cancer immunotherapy

(2016) Maria Stella Sasso et al.   BIOMATERIALS

Immunotherapy and tumor microenvironment

(2016) Haidong Tang et al.   CANCER LETTERS

Overcoming barriers to effective immunotherapy: MDSCs, TAMs, and Tregs as mediators of the immunosuppressive microenvironment in head and neck cancer

(2016) Ruth J. Davis et al.   ORAL ONCOLOGY

Nanogel-Incorporated Physical and Chemical Hybrid Gels for Highly Effective Chemo-Protein Combination Therapy

(2015) Xilong Wu et al.   ADVANCED FUNCTIONAL MATERIALS

Adjuvant Immunotherapy With Autologous Cytokine-Induced Killer Cells for Hepatocellular Carcinoma

(2015) Joon Hyeok Lee et al.   GASTROENTEROLOGY

Synthetic immunobiology boosts the IQ of T cells

(2015) M. C. Jensen   SCIENCE

Adoptive cell transfer as personalized immunotherapy for human cancer

(2015) S. A. Rosenberg et al.   SCIENCE

Biopolymer implants enhance the efficacy of adoptive T-cell therapy

(2014) Sirkka B Stephan et al.   NATURE BIOTECHNOLOGY

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Decisive Role of Hydrophobic Side Groups of Polypeptides in Thermosensitive Gelation

(2012) Yilong Cheng et al.   BIOMACROMOLECULES

Characterization and antitumor activities of the water-soluble polysaccharide from Rhizoma Arisaematis

(2012) Geng Chen et al.   CARBOHYDRATE POLYMERS

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

(2012) Abhishek D Garg et al.   EMBO JOURNAL

Supramolecular hydrogels as a universal scaffold for stepwise delivering Dox and Dox/cisplatin loaded block copolymer micelles

(2012) Wen Zhu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Biodegradable Thermogels

(2011) Min Hee Park et al.   ACCOUNTS OF CHEMICAL RESEARCH

Effect of millimeter waves and cyclophosphamide on cytokine regulation

(2011) Mahendra K. Logani et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Adoptive transfer of pTRP2-specific CTLs expanding by bead-based artificial antigen-presenting cells mediates anti-melanoma response

(2008) Xiaoling Lu et al.   CANCER LETTERS

Injectable hydrogels as unique biomedical materials

(2008) Lin Yu et al.   CHEMICAL SOCIETY REVIEWS

In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery

(2008) Chaoliang He et al.   JOURNAL OF CONTROLLED RELEASE