Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases

Increased Mean Platelet Volume in Familial Hypercholesterolemia

(2015) Atilla Icli et al.   ANGIOLOGY

Association Between Inflammatory Bowel Disease and Vitamin D Deficiency

(2015) Rita Del Pinto et al.   INFLAMMATORY BOWEL DISEASES

The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease

(2014) Grant P. Parnell et al.   CLINICAL IMMUNOLOGY

Dendritic cells as targets or therapeutics in rheumatic autoimmune disease

(2014) Ranjeny Thomas   CURRENT OPINION IN RHEUMATOLOGY

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells

(2014) Makoto Kurachi et al.   NATURE IMMUNOLOGY

Patterns of Genome-Wide VDR Locations

(2014) Pauli Tuoresmäki et al.   PLoS One

Associations between serum 25-hydroxyvitamin D and disease activity, inflammatory cytokines and bone loss in patients with rheumatoid arthritis

(2014) Q. Hong et al.   RHEUMATOLOGY

Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells

(2014) M. N. Lee et al.   SCIENCE

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

Mean Platelet Volume and Vitamin D Level

(2014) Medine Cumhur Cure et al.   Annals of Laboratory Medicine

Tolerogenic dendritic cell vaccines to treat autoimmune diseases: Can the unattainable dream turn into reality?

(2013) Ilse Van Brussel et al.   AUTOIMMUNITY REVIEWS

Geographic Variation in the Prevalence of Attention-Deficit/Hyperactivity Disorder: The Sunny Perspective

(2013) Martijn Arns et al.   BIOLOGICAL PSYCHIATRY

A Vitamin D Receptor/SMAD Genomic Circuit Gates Hepatic Fibrotic Response

(2013) Ning Ding et al.   CELL

Vitamin D and systemic lupus erythematosus: an update

(2013) Chi Chiu Mok   Expert Review of Clinical Immunology

The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells

(2013) Fernando Shahijanian et al.   HUMAN MOLECULAR GENETICS

Vitamin D Status and Concomitant Autoimmunity in Celiac Disease

(2013) Anna Tavakkoli et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Active Crohn's disease is associated with low vitamin D levels

(2013) Søren Peter Jørgensen et al.   Journal of Crohns & Colitis

Prostaglandin E2 imprints a long-lasting effect on dendritic cell progenitors in the bone marrow

(2013) Naomi M. Scott et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Genetic insights into common pathways and complex relationships among immune-mediated diseases

(2013) Miles Parkes et al.   NATURE REVIEWS GENETICS

Geographical variation and incidence of inflammatory bowel disease among US women

(2012) Hamed Khalili et al.   GUT

Dendritic Cells and Multiple Sclerosis: Disease, Tolerance and Therapy

(2012) Mohammad Mohammad et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Nuclear Hormone Receptors Enable Macrophages and Dendritic Cells to Sense Their Lipid Environment and Shape Their Immune Response

(2012) Laszlo Nagy et al.   PHYSIOLOGICAL REVIEWS

Immune-mediated disease genetics: the shared basis of pathogenesis

(2012) Chris Cotsapas et al.   TRENDS IN IMMUNOLOGY

Vitamin D and its emerging role in immunopathology

(2011) Muhammad Haroon et al.   CLINICAL RHEUMATOLOGY

Latitude is significantly associated with the prevalence of multiple sclerosis: a meta-analysis

(2011) S. Simpson et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Vitamin D–gene interactions in multiple sclerosis

(2011) Antonio J. Berlanga-Taylor et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Prevention and treatment of MS: studying the effects of vitamin D

(2011) Kassandra L Munger et al.   Multiple Sclerosis Journal

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Pervasive Sharing of Genetic Effects in Autoimmune Disease

(2011) Chris Cotsapas et al.   PLoS Genetics

Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci

(2011) Alexandra Zhernakova et al.   PLoS Genetics

Association between Residences in U.S. Northern Latitudes and Rheumatoid Arthritis: A Spatial Analysis of the Nurses’ Health Study

(2010) Verónica M. Vieira et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Bcl-6 and NF- B cistromes mediate opposing regulation of the innate immune response

(2010) G. D. Barish et al.   GENES & DEVELOPMENT

A ChIP-seq defined genome-wide map of vitamin D receptor binding: Associations with disease and evolution

(2010) S. V. Ramagopalan et al.   GENOME RESEARCH

Low serum levels of 25-hydroxyvitamin D (25-OHD) among psychiatric out-patients in Sweden: Relations with season, age, ethnic origin and psychiatric diagnosis

(2010) Mats B. Humble et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Vitamin D and multiple sclerosis

(2010) Alberto Ascherio et al.   LANCET NEUROLOGY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Dendritic cell tolerogenicity: a key mechanism in immunomodulation by vitamin D receptor agonists

(2009) Luciano Adorini et al.   HUMAN IMMUNOLOGY

1,25-Dihydroxyvitamin D3 Is an Autonomous Regulator of the Transcriptional Changes Leading to a Tolerogenic Dendritic Cell Phenotype

(2009) L. Szeles et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

(2009) Melanie Bahlo et al.   NATURE GENETICS

Vitamin D Status Is Positively Correlated with Regulatory T Cell Function in Patients with Multiple Sclerosis

(2009) Joost Smolders et al.   PLoS One

Look Who's Talking: Nuclear Receptors in the Liver and Gastrointestinal Tract

(2008) Michael Downes et al.   Cell Metabolism