SF3B1/Hsh155 HEAT motif mutations affect interaction with the spliceosomal ATPase Prp5, resulting in altered branch site selectivity in pre-mRNA splicing
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
SF3B1/Hsh155 HEAT motif mutations affect interaction with the spliceosomal ATPase Prp5, resulting in altered branch site selectivity in pre-mRNA splicing
Authors
Keywords
-
Journal
GENES & DEVELOPMENT
Volume 30, Issue 24, Pages 2710-2723
Publisher
Cold Spring Harbor Laboratory
Online
2017-01-14
DOI
10.1101/gad.291872.116
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites
- (2016) Daniel R. Semlow et al. CELL
- Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations
- (2016) Constantin Cretu et al. MOLECULAR CELL
- Cryo-EM structure of the spliceosome immediately after branching
- (2016) Wojciech P. Galej et al. NATURE
- Structure of a yeast catalytic step I spliceosome at 3.4 A resolution
- (2016) R. Wan et al. SCIENCE
- Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
- (2016) R. Rauhut et al. SCIENCE
- Structure of a yeast activated spliceosome at 3.5 A resolution
- (2016) C. Yan et al. SCIENCE
- Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage
- (2016) Samar Alsafadi et al. Nature Communications
- A novel mechanism for Prp5 function in prespliceosome formation and proofreading the branch site sequence
- (2015) Wen-Wei Liang et al. GENES & DEVELOPMENT
- Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes
- (2015) A Sveen et al. ONCOGENE
- Cancer-Associated SF3B1 Hotspot Mutations Induce Cryptic 3′ Splice Site Selection through Use of a Different Branch Point
- (2015) Rachel B. Darman et al. Cell Reports
- Transcriptome Sequencing Reveals Potential Mechanism of Cryptic 3’ Splice Site Selection in SF3B1-mutated Cancers
- (2015) Christopher DeBoever et al. PLoS Computational Biology
- Rare SF3B1 R625 mutations in cutaneous melanoma
- (2014) Yong Kong et al. MELANOMA RESEARCH
- SF3B1 mutations in chronic lymphocytic leukemia
- (2013) Y. Wan et al. BLOOD
- Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia
- (2013) Dan A. Landau et al. CELL
- Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2
- (2013) J C Strefford et al. LEUKEMIA
- Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma
- (2013) J William Harbour et al. NATURE GENETICS
- Splicing proofreading at 5′ splice sites by ATPase Prp28p
- (2013) Fei Yang et al. NUCLEIC ACIDS RESEARCH
- Splicing fidelity
- (2013) Prakash Koodathingal et al. RNA Biology
- SF3B1 Mutations Are Associated with Alternative Splicing in Uveal Melanoma
- (2013) S. J. Furney et al. Cancer Discovery
- Misregulation of Pre-mRNA Alternative Splicing in Cancer
- (2013) J. Zhang et al. Cancer Discovery
- Crystal Structure of Prp5p Reveals Interdomain Interactions that Impact Spliceosome Assembly
- (2013) Zhi-Min Zhang et al. Cell Reports
- SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes
- (2012) V. Visconte et al. BLOOD
- Whole-genome analysis informs breast cancer response to aromatase inhibition
- (2012) Matthew J. Ellis et al. NATURE
- Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
- (2012) Andrew V. Biankin et al. NATURE
- Spliceosome Database: a tool for tracking components of the spliceosome
- (2012) Ivan Cvitkovic et al. NUCLEIC ACIDS RESEARCH
- The spliceosome: a flexible, reversible macromolecular machine
- (2012) Aaron A. Hoskins et al. TRENDS IN BIOCHEMICAL SCIENCES
- Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
- (2011) L. Malcovati et al. BLOOD
- Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness
- (2011) D. Rossi et al. BLOOD
- The Spliceosome as an Indicted Conspirator in Myeloid Malignancies
- (2011) Omar Abdel-Wahab et al. CANCER CELL
- A U1-U2 snRNP Interaction Network during Intron Definition
- (2011) W. Shao et al. MOLECULAR AND CELLULAR BIOLOGY
- Frequent pathway mutations of splicing machinery in myelodysplasia
- (2011) Kenichi Yoshida et al. NATURE
- Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
- (2011) Víctor Quesada et al. NATURE GENETICS
- Spliceosome mutations in hematopoietic malignancies
- (2011) Christopher N Hahn et al. NATURE GENETICS
- SomaticSF3B1Mutation in Myelodysplasia with Ring Sideroblasts
- (2011) E. Papaemmanuil et al. NEW ENGLAND JOURNAL OF MEDICINE
- SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
- (2011) Lili Wang et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
- (2010) A. McKenna et al. GENOME RESEARCH
- Release of SF3 from the intron branchpoint activates the first step of pre-mRNA splicing
- (2010) R. M. Lardelli et al. RNA
- A systematic CEN library of the Saccharomyces cerevisiae genome
- (2010) Kelli L. Hvorecny et al. YEAST
- Spliceosome Structure and Function
- (2010) C. L. Will et al. Cold Spring Harbor Perspectives in Biology
- Fast and accurate short read alignment with Burrows-Wheeler transform
- (2009) H. Li et al. BIOINFORMATICS
- The Spliceosome: Design Principles of a Dynamic RNP Machine
- (2009) Markus C. Wahl et al. CELL
- Reconstitution of both steps of Saccharomyces cerevisiae splicing with purified spliceosomal components
- (2009) Zbigniew Warkocki et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Alternative splicing and disease
- (2008) Jamal Tazi et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started