An in vivo selection system with tightly regulated gene expression enables directed evolution of highly efficient enzymes

Structure-based directed evolution improves S. cerevisiae growth on xylose by influencing in vivo enzyme performance

(2020) Misun Lee et al.   Biotechnology for Biofuels

Re-epithelialization and immune cell behaviour in an ex vivo human skin model

(2020) Ana Rakita et al.   Scientific Reports

Engineering new catalytic activities in enzymes

(2020) Kai Chen et al.   Nature Catalysis

The developing toolkit of continuous directed evolution

(2020) Mary S. Morrison et al.   Nature Chemical Biology

Intracellular selection of trans-cleaving hammerhead ribozymes

(2019) Xin Huang et al.   NUCLEIC ACIDS RESEARCH

β-Lactamases and β-Lactamase Inhibitors in the 21st Century

(2019) Catherine L. Tooke et al.   JOURNAL OF MOLECULAR BIOLOGY

A Novel Synthetic Toehold Switch for MicroRNA Detection in Mammalian Cells

(2019) Shue Wang et al.   ACS Synthetic Biology

Directed Evolution of Protein Catalysts

(2018) Cathleen Zeymer et al.   Annual Review of Biochemistry

Riboregulator elements as tools to engineer gene expression in cyanobacteria

(2018) Kinuko Ueno et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future

(2015) James Chappell et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

A Triple Mutant in the Ω-loop of TEM-1 β-Lactamase Changes the Substrate Profile via a Large Conformational Change and an Altered General Base for Catalysis

(2015) Vlatko Stojanoski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tunable Riboregulator Switches for Post-transcriptional Control of Gene Expression

(2015) Malathy Krishnamurthy et al.   ACS Synthetic Biology

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

An N-Terminal Protein Degradation Tag Enables Robust Selection of Highly Active Enzymes

(2011) Maren Butz et al.   BIOCHEMISTRY

Engineering Biological Systems with Synthetic RNA Molecules

(2011) Joe C. Liang et al.   MOLECULAR CELL

Multiple Global Suppressors of Protein Stability Defects Facilitate the Evolution of Extended-Spectrum TEM β-Lactamases

(2010) Nicholas G. Brown et al.   JOURNAL OF MOLECULAR BIOLOGY

VARNA: Interactive drawing and editing of the RNA secondary structure

(2009) Kévin Darty et al.   BIOINFORMATICS

In the light of directed evolution: Pathways of adaptive protein evolution

(2009) J. D. Bloom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Design by Directed Evolution

(2008) Christian Jäckel et al.   Annual Review of Biophysics