A Triple Mutant in the Ω-loop of TEM-1 β-Lactamase Changes the Substrate Profile via a Large Conformational Change and an Altered General Base for Catalysis

Evolution of Drug Resistance: Insight on TEM β-Lactamases Structure and Activity and β-Lactam Antibiotics

(2014) A.C. Pimenta et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Mutations inducing an active-site aperture inRhizobiumsp. sucrose isomerase confer hydrolytic activity

(2013) Alexandra Lipski et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Resistance to the Third-Generation Cephalosporin Ceftazidime by a Deacylation-Deficient Mutant of the TEM β-Lactamase by the Uncommon Covalent-Trapping Mechanism

(2011) Nuno T. Antunes et al.   BIOCHEMISTRY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

TEM-1 Backbone Dynamics—Insights from Combined Molecular Dynamics and Nuclear Magnetic Resonance

(2010) Olivier Fisette et al.   BIOPHYSICAL JOURNAL

Resistance to cephalosporins and carbapenems in Gram-negative bacterial pathogens

(2010) Yvonne Pfeifer et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Molecular replacement withMOLREP

(2009) Alexei Vagin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Updated Functional Classification of  -Lactamases

(2009) K. Bush et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Three Decades of the Class A β-Lactamase Acyl-Enzyme

(2009) Jed Fisher et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Structural and Biochemical Evidence That a TEM-1 β-Lactamase N170G Active Site Mutant Acts via Substrate-assisted Catalysis

(2009) Nicholas G. Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Extended-spectrum β-lactamases: structure and kinetic mechanism

(2008) M.G.P. Page   CLINICAL MICROBIOLOGY AND INFECTION

Genetic and Structural Characterization of an L201P Global Suppressor Substitution in TEM-1 β-Lactamase

(2008) David C. Marciano et al.   JOURNAL OF MOLECULAR BIOLOGY