Cystine–glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice
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Title
Cystine–glutamate antiporter deletion accelerates motor recovery and improves histological outcomes following spinal cord injury in mice
Authors
Keywords
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Journal
Scientific Reports
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-06-09
DOI
10.1038/s41598-021-91698-y
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Note: Only part of the references are listed.- Semi-quantitative distribution of excitatory amino acid (glutamate) transporters 1-3 (EAAT1-3) and the cystine-glutamate exchanger (xCT) in the adult murine spinal cord
- (2020) Qiu-Xiang Hu et al. NEUROCHEMISTRY INTERNATIONAL
- System xc− in microglia is a novel therapeutic target for post-septic neurological and psychiatric illness
- (2019) Yoshinori Kitagawa et al. Scientific Reports
- Genetic deletion of xCT attenuates peripheral and central inflammation and mitigates LPS-induced sickness and depressive-like behavior in mice
- (2018) Giulia Albertini et al. GLIA
- Lipocalin 2 Plays an Important Role in Regulating Inflammation in Retinal Degeneration
- (2018) Tanu Parmar et al. JOURNAL OF IMMUNOLOGY
- Normal aging induces A1-like astrocyte reactivity
- (2018) Laura E. Clarke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regional oligodendrocytopathy and astrocytopathy precede myelin loss and blood-brain barrier disruption in a murine model of osmotic demyelination syndrome
- (2017) Joanna Bouchat et al. GLIA
- Absence of system xc − on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis
- (2017) Ellen Merckx et al. Journal of Neuroinflammation
- Lipocalin-2 protects the brain during inflammatory conditions
- (2017) S S Kang et al. MOLECULAR PSYCHIATRY
- Cystine/glutamate antiporter blockage induces myelin degeneration
- (2016) Federico N. Soria et al. GLIA
- PET Imaging with [18F]FSPG Evidences the Role of System xc- on Brain Inflammation Following Cerebral Ischemia in Rats
- (2016) Maria Domercq et al. Theranostics
- Cellular and subcellular oxidative stress parameters following severe spinal cord injury
- (2016) Nishant P. Visavadiya et al. Redox Biology
- A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System xc− Mediates Aglycemic Neuronal Cell Death
- (2015) Trista L. Thorn et al. ASN Neuro
- Interleukin-1β protects astrocytes against oxidant-induced injury via an NF-κB-Dependent upregulation of glutathione synthesis
- (2015) Yan He et al. GLIA
- Inhibition of SystemXc−Transporter Attenuates Autoimmune Inflammatory Demyelination
- (2015) Kirsten S. Evonuk et al. JOURNAL OF IMMUNOLOGY
- Main path and byways: non-vesicular glutamate release by system xc−as an important modifier of glutamatergic neurotransmission
- (2015) Ann Massie et al. JOURNAL OF NEUROCHEMISTRY
- System xC− is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice
- (2014) Pinar Mesci et al. BRAIN
- Phenotypic Polarization of Activated Astrocytes: The Critical Role of Lipocalin-2 in the Classical Inflammatory Activation of Astrocytes
- (2013) E. Jang et al. JOURNAL OF IMMUNOLOGY
- Temporal changes in monocyte and macrophage subsets and microglial macrophages following spinal cord injury in the lys-egfp-ki mouse model
- (2013) Sakina G. Thawer et al. JOURNAL OF NEUROIMMUNOLOGY
- The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities
- (2012) Jan Lewerenz et al. ANTIOXIDANTS & REDOX SIGNALING
- Non-Cell Autonomous Influence of the Astrocyte System xc− on Hypoglycaemic Neuronal Cell Death
- (2012) Nicole A Jackman et al. ASN Neuro
- Phrenic motor neuron degeneration compromises phrenic axonal circuitry and diaphragm activity in a unilateral cervical contusion model of spinal cord injury
- (2012) Charles Nicaise et al. EXPERIMENTAL NEUROLOGY
- Degeneration of Phrenic Motor Neurons Induces Long-Term Diaphragm Deficits following Mid-Cervical Spinal Contusion in Mice
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- System xc− regulates microglia and macrophage glutamate excitotoxicity in vivo
- (2011) Kristina A. Kigerl et al. EXPERIMENTAL NEUROLOGY
- Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration
- (2011) Jacque PK Ip et al. Journal of Neuroinflammation
- Increased expression of cystine/glutamate antiporter in multiple sclerosis
- (2011) Olatz Pampliega et al. Journal of Neuroinflammation
- Lipocalin 2 Plays an Immunomodulatory Role and Has Detrimental Effects after Spinal Cord Injury
- (2011) K. I. Rathore et al. JOURNAL OF NEUROSCIENCE
- Loss of System xFormula Does Not Induce Oxidative Stress But Decreases Extracellular Glutamate in Hippocampus and Influences Spatial Working Memory and Limbic Seizure Susceptibility
- (2011) D. De Bundel et al. JOURNAL OF NEUROSCIENCE
- Repertoire of microglial and macrophage responses after spinal cord injury
- (2011) Samuel David et al. NATURE REVIEWS NEUROSCIENCE
- Oligodendrocyte Fate after Spinal Cord Injury
- (2011) Akshata Almad et al. Neurotherapeutics
- Dopaminergic neurons of system xc−-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity
- (2010) Ann Massie et al. FASEB JOURNAL
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- Lipocalin-2 Is an Autocrine Mediator of Reactive Astrocytosis
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- Gliopathy ensures persistent inflammation and chronic pain after spinal cord injury
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