A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System xc− Mediates Aglycemic Neuronal Cell Death

Interleukin-1β protects astrocytes against oxidant-induced injury via an NF-κB-Dependent upregulation of glutathione synthesis

(2015) Yan He et al.   GLIA

The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities

(2012) Jan Lewerenz et al.   ANTIOXIDANTS & REDOX SIGNALING

Non-Cell Autonomous Influence of the Astrocyte System xc− on Hypoglycaemic Neuronal Cell Death

(2012) Nicole A Jackman et al.   ASN Neuro

Pre-Conditioning Induces the Precocious Differentiation of Neonatal Astrocytes to Enhance Their Neuroprotective Properties

(2011) Ellora Sen et al.   ASN Neuro

Loss of System xFormula Does Not Induce Oxidative Stress But Decreases Extracellular Glutamate in Hippocampus and Influences Spatial Working Memory and Limbic Seizure Susceptibility

(2011) D. De Bundel et al.   JOURNAL OF NEUROSCIENCE

Dopaminergic neurons of system xc−-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity

(2010) Ann Massie et al.   FASEB JOURNAL

Regulation of System xc−Activity and Expression in Astrocytes by Interleukin-1β

(2010) Nicole A. Jackman et al.   GLIA

Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data

(2009) D. E. G. Griesdale et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxonein vitro

(2009) Jan Lewerenz et al.   JOURNAL OF NEUROCHEMISTRY

A role for glutamate in growth and invasion of primary brain tumors

(2008) Harald Sontheimer   JOURNAL OF NEUROCHEMISTRY

Uridine Protects Cortical Neurons from Glucose Deprivation-Induced Death: Possible Role of Uridine Phosphorylase

(2008) Ji Woong Choi et al.   JOURNAL OF NEUROTRAUMA

Small interfering RNA–mediated xCT silencing in gliomas inhibits neurodegeneration and alleviates brain edema

(2008) Nicolai E Savaskan et al.   NATURE MEDICINE

Robust glycogen shunt activity in astrocytes: Effects of glutamatergic and adrenergic agents

(2008) A.B. Walls et al.   NEUROSCIENCE

SIN-1-induced cytotoxicity in mixed cortical cell culture: peroxynitrite-dependent and -independent induction of excitotoxic cell death

(2003) Joseph L. Trackey et al.   JOURNAL OF NEUROCHEMISTRY

Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function

(2003) Steven W. Barger et al.   JOURNAL OF NEUROCHEMISTRY