Sitagliptin attenuates arterial calcification by downregulating oxidative stress-induced receptor for advanced glycation end products in LDLR knockout mice
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Sitagliptin attenuates arterial calcification by downregulating oxidative stress-induced receptor for advanced glycation end products in LDLR knockout mice
Authors
Keywords
-
Journal
Scientific Reports
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-09-08
DOI
10.1038/s41598-021-97361-w
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Carcinogenesis and Reactive Oxygen Species Signaling: Interaction of the NADPH Oxidase NOX1–5 and Superoxide Dismutase 1–3 Signal Transduction Pathways
- (2018) Alessia Parascandolo et al. ANTIOXIDANTS & REDOX SIGNALING
- Teneligliptin, a dipeptidyl peptidase-4 inhibitor, attenuated pro-inflammatory phenotype of perivascular adipose tissue and inhibited atherogenesis in normoglycemic apolipoprotein-E-deficient mice
- (2017) Hotimah Masdan Salim et al. VASCULAR PHARMACOLOGY
- Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE)
- (2016) Tomoya Mita et al. DIABETES CARE
- Sitagliptin inhibits endothelin-1 expression in the aortic endothelium of rats with streptozotocin-induced diabetes by suppressing the nuclear factor-κB/IκBα system through the activation of AMP-activated protein kinase
- (2016) SONG-TAO TANG et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Anti-Inflammatory Effects of GLP-1-Based Therapies beyond Glucose Control
- (2016) Young-Sun Lee et al. MEDIATORS OF INFLAMMATION
- Sitagliptin attenuates cardiomyopathy by modulating the JAK/STAT signaling pathway in experimental diabetic rats
- (2016) Ayman Mahmoud et al. Drug Design Development and Therapy
- The Role of AGE/RAGE Signaling in Diabetes-Mediated Vascular Calcification
- (2016) Amber M. Kay et al. Journal of Diabetes Research
- Correction: Simvastatin Attenuates Oxidative Stress, NF-κB Activation, and Artery Calcification in LDLR-/- Mice Fed with High Fat Diet via Down-regulation of Tumor Necrosis Factor-α and TNF Receptor 1
- (2016) Chih-Pei Lin et al. PLoS One
- S100A12 and the S100/CalgranulinsSignificance
- (2015) Adam Oesterle et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- The receptor for advanced glycation end products and risk of peripheral arterial disease, amputation or death in type 2 diabetes: a population-based cohort study
- (2015) Jonas Malmstedt et al. Cardiovascular Diabetology
- Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A)
- (2015) Tomoya Mita et al. DIABETES CARE
- Induction of Energy Expenditure by Sitagliptin Is Dependent on GLP-1 Receptor
- (2015) Felicia Goldsmith et al. PLoS One
- A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-Cells in Type 2 Diabetic Mice
- (2015) Chunbing Zheng et al. PLoS One
- Vascular calcification: Mechanisms of vascular smooth muscle cell calcification
- (2015) Jane A. Leopold TRENDS IN CARDIOVASCULAR MEDICINE
- The DPP-4 inhibitor sitagliptin attenuates the progress of atherosclerosis in apolipoprotein-E-knockout mice via AMPK- and MAPK-dependent mechanisms
- (2014) Yanmei Zeng et al. Cardiovascular Diabetology
- Mechanisms of Medial Arterial Calcification in Diabetes
- (2014) Dimitry Chistiakov et al. CURRENT PHARMACEUTICAL DESIGN
- Significance of Vascular Dipeptidyl Peptidase-4 Inhibition on Vascular Protection in Zucker Diabetic Fatty Rats
- (2014) Shinji Takai et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Advanced glycation end products accelerate rat vascular calcification through RAGE/oxidative stress
- (2013) Qin Wei et al. BMC Cardiovascular Disorders
- RAGE regulation and signaling in inflammation and beyond
- (2013) Katrin Kierdorf et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Advanced glycation end-product Nɛ-carboxymethyl-Lysine accelerates progression of atherosclerotic calcification in diabetes
- (2012) Zhongqun Wang et al. ATHEROSCLEROSIS
- Smooth Muscle Cell–Specific Runx2 Deficiency Inhibits Vascular Calcification
- (2012) Yong Sun et al. CIRCULATION RESEARCH
- Vascular Calcification: Pathophysiology and Risk Factors
- (2012) Neal X. Chen et al. CURRENT HYPERTENSION REPORTS
- Advanced Glycation End Products-induced Vascular Calcification is Mediated by Oxidative Stress: Functional Roles of NAD(P)H-oxidase
- (2012) Y. Tada et al. HORMONE AND METABOLIC RESEARCH
- Molecular Imaging Insights Into Early Inflammatory Stages of Arterial and Aortic Valve Calcification
- (2011) Sophie E.P. New et al. CIRCULATION RESEARCH
- Type 2-diabetes is associated with elevated levels of TNF-alpha, IL-6 and adiponectin and low levels of leptin in a population of Mexican Americans: A cross-sectional study
- (2011) S. Mirza et al. CYTOKINE
- DPP-4 inhibitors in the management of type 2 diabetes: A critical review of head-to-head trials
- (2011) A.J. Scheen DIABETES & METABOLISM
- Incretin effect: GLP-1, GIP, DPP4
- (2011) Kyriakos Kazakos DIABETES RESEARCH AND CLINICAL PRACTICE
- Novel Biological Action of the Dipeptidylpeptidase-IV Inhibitor, Sitagliptin, as a Glucagon-Like Peptide-1 Secretagogue
- (2011) Ganesh V. Sangle et al. ENDOCRINOLOGY
- DPP-4 (CD26) Inhibitor Alogliptin Inhibits Atherosclerosis in Diabetic Apolipoprotein E–Deficient Mice
- (2011) Nga N Ta et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Serum levels of soluble receptor for advanced glycation endproducts (sRAGE) are higher in ulcerative colitis and correlate with disease activity
- (2011) Y. Yilmaz et al. Journal of Crohns & Colitis
- Dipeptidyl peptidase IV inhibitor sitagliptin reduces local inflammation in adipose tissue and in pancreatic islets of obese mice
- (2010) A. D. Dobrian et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- S100A12 in Vascular Smooth Muscle Accelerates Vascular Calcification in Apolipoprotein E–Null Mice by Activating an Osteogenic Gene Regulatory Program
- (2010) Marion A. Hofmann Bowman et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Nrf-2 mediated heme oxygenase-1 expression, an antioxidant-independent mechanism, contributes to anti-atherogenesis and vascular protective effects of Ginkgo biloba extract
- (2010) Jia-Shiong Chen et al. ATHEROSCLEROSIS
- The RAGE Axis
- (2010) Shi Fang Yan et al. CIRCULATION RESEARCH
- Blood Pressure and Vascular Calcification
- (2010) Nicole E. Jensky et al. HYPERTENSION
- Effect of high glucose levels on the calcification of vascular smooth muscle cells by inducing osteoblastic differentiation and intracellular calcium deposition via BMP-2/Cbfα-1 pathway
- (2010) Fang Liu et al. Journal of Zhejiang University-SCIENCE B
- Characterization of RAGE, HMGB1, and S100β in Inflammation-Induced Preterm Birth and Fetal Tissue Injury
- (2009) Catalin S. Buhimschi et al. AMERICAN JOURNAL OF PATHOLOGY
- RAGE mediates oxidized LDL-induced pro-inflammatory effects and atherosclerosis in non-diabetic LDL receptor-deficient mice
- (2009) L. Sun et al. CARDIOVASCULAR RESEARCH
- Advanced Glycation End Products Induce Calcification of Vascular Smooth Muscle Cells through RAGE/p38 MAPK
- (2009) Takahisa Tanikawa et al. JOURNAL OF VASCULAR RESEARCH
- Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling
- (2008) Chang Hyun Byon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More